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All Journal JOPS (Journal Of Pharmacy and Science) Journal of Pharmacy and Nutrition Research
Wutsqa, Yusfia Urwatul
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Formulation and Evaluation of Ointment Preparations with Nutgrass Extract (Cyperus rotundus L.) Using Different Ointment Bases Wutsqa, Yusfia Urwatul; Munif, Abdul; Sari, Dwi Retno
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.4199

Abstract

Nutgrass (Cyperus rotundus L.) is a medicinal plant that belongs to the Cyperaceae family. Nutgrass (Cyperus rotundus L.) is often used as a remedy to treat diseases caused by bacterial activity such as skin itching, boils, and vaginal discharge. The aim of this research is to determine the physical properties of the ointment containing nutgrass extract (Cyperus rotundus L.). Nutgrass (Cyperus rotundus L.) is extracted using 70% ethanol solvent and then formulated into ointments with different concentrations of hydrocarbon and absorbent bases. The ointment preparations made consist of three formulations with extract concentrations of 20%, 30%, and 40% to allow for comparison. The evaluation tests for the ointment preparations containing nutgrass extract (Cyperus rotundus L.) include organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests, and stability tests. The analysis method used in this research is descriptive, which involves describing the results of the formulations of ointment preparations with nutgrass extract (Cyperus rotundus L.). The research results indicate that ethanol extract can be formulated into ointment preparations, and there are several tests that meet the evaluation criteria, namely organoleptic tests, adhesion tests, and homogeneity tests.
Utilization of Methanol Extract Sea Pandan Fruit (Pandanus tectorius) in Hand and Body Cream as an Antioxidants Retno Sari, Dwi; Wutsqa, Yusfia Urwatul; Hikmah, Siti Nur
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.4706

Abstract

Sea pandanus is a coastal plant with great potential in the cosmetic industry due to its rich contains phenolic and flavonoid compounds that are abundant in the fruits. The purpose of this research is determine the antioxidant activity of sea pandanus fruit and to evaluate the result of hand and body cream formulation. Pandanus was chosen because it is not widely explored.The result of study showed that the methanol extract of sea pandanus contains phenolic, flavonoid, saponin, and steroid compounds. The antioxidant activity in the hand and body cream formulation was 33,183 µg/mL, indicating strong antioxidant activity below the IC50. The high level antioxidant activity from the methanol extract of sea pandanus can be used in the formulation of hand and body cream. Characteristics in the quality assessment of all the hand and body cream did not meet the requirements.
Efek Konseling Farmasi pada Kualitas Hidup dan Gula Darah Pasien Diabetes Melitus Tipe 2 : The Effect of Pharmacy Counseling on The Quality of Life and Blood Sugar Levels of Type 2 Diabetes Mellitus Patients Istiqomah, Iis; Sari, Dwi Retno; Muhammad Fauzi, Fawwaz; Wutsqa, Yusfia Urwatul
Journal of Pharmacy and Nutrition Research Vol. 1 No. 01 (2025): June, 2025
Publisher : LPPM STIKes KHAS Kempek

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64689/jopanur.v1i01.4

Abstract

Diabetes Melitus (DM) adalah penyakit tidak menular yang sulit disembuhkan dan dapat menyebabkan kematian jika tidak dikelola dengan tepat. Konseling farmasi kepada pasien DM dapat meningkatkan pemahaman terhadap penyakit, sehingga berpotensi meningkatkan efektivitas pengobatan baik secara farmakologis maupun non-farmakologis, serta memperbaiki kualitas hidup pasien. Penelitian ini bertujuan mengkaji dampak konseling farmasi terhadap kualitas hidup dan kadar gula darah pasien DM tipe 2 sebelum dan sesudah intervensi. Penelitian menggunakan rancangan kuasi-eksperimen dengan pendekatan pre-test dan post-test. Alat ukur yang digunakan adalah kuesioner Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) untuk menilai kualitas hidup, serta pemeriksaan kadar gula darah sewaktu sebagai parameter klinis. Sebanyak 23 responden dipilih secara purposive sampling sesuai kriteria inklusi. Hasil analisis menggunakan paired sample t-test menunjukkan bahwa konseling farmasi berdampak signifikan terhadap peningkatan kualitas hidup pasien, dengan rata-rata skor meningkat dari 188,70 menjadi 206,17 (p = 0,00). Selain itu, terjadi penurunan rerata kadar gula darah sewaktu dari 337,91 mg/dL menjadi 285,17 mg/dL setelah intervensi (p = 0,00). Dengan demikian, konseling farmasi terbukti berperan positif dalam meningkatkan kualitas hidup dan menurunkan kadar gula darah sewaktu pada pasien DM tipe 2 di Puskesmas Palimanan, Kabupaten Cirebon.
Co-Authors ABDUL MUNIF Dwi Retno Sari, Dwi Retno Hikmah, Siti Nur Istiqomah, Iis Muhammad Fauzi, Fawwaz Retno Sari, Dwi