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All Journal MNJ (Malang Neurology Journal) NUSANTARA: Jurnal Pengabdian Kepada Masyarakat Devotion : Jurnal Pengabdian Psikologi
Huwae, Laura Bianca Sylvia
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Academic Culture Shock Workshop as a Strategy to Improve Students'Mental Readiness in the Academic Environment of the Faculty of Medicine Rugebregt, Joanne; Rugebregt, Joanne Marrijda; Noya, Farah Christina; Saija, Alessandra Flowrence; Safutra, Muhamad Sadam; Wade Marlinda; Huwae, Laura Bianca Sylvia; Bension, Johan Bruiyf
Devotion : Jurnal Pengabdian Psikologi Vol. 4 No. 02 (2025): November
Publisher : Fakultas Psikologi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64228/r7267326

Abstract

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Identifikasi Tekanan Darah Tinggi pada Warga Binaan Rumah Tahanan Kelas II B Masohi Tahun 2025 Leiwakabessy, Jusuf; Huwae, Laura Bianca Sylvia; Tentua, Vebiyanti; Febriani, Reka; Bastian, Gustino Anjelo; Dyahnissa, Rahma; Rusmin, Rusdiah Marhumi
Nusantara: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 1 (2026): Februari: NUSANTARA Jurnal Pengabdian Kepada Masyarakat
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/nusantara.v6i1.7404

Abstract

Blood pressure is the pressure exerted by blood pumped by the heart against the walls of the arteries. Abnormalities in blood pressure can take the form of high blood pressure or hypertension and low blood pressure or hypotension. Hypertension is a non-communicable disease that is one of the risk factors for cardiovascular disease, and sufferers often do not show any symptoms. This community service activity aimed to examine the results of blood pressure measurements among inmates at the Class IIB Detention Center in Masohi City. This study used a descriptive observational design with a cross-sectional approach. There were 95 inmates who participated in this activity. Data analysis was conducted using quantitative descriptive methods to describe the blood pressure measurement results based on demographic data such as age, gender, education level, occupation, height, and weight. The results showed that most respondents were in the 20-30 age range (44.2%) and male (91.6%). The level of education shows that most respondents only completed high school (54.7%) and the majority worked as farmers (30.5%). Anthropometric characteristics in terms of height show that most respondents were between 140-160 cm (47.4%) and weighed between 51-60 kg (43.2%). The distribution of blood pressure shows that most respondents are in the pre-hypertension (40%), normal (29.5%), grade 1 hypertension (17.9%), and grade 2 hypertension (10.5%). Therefore, routine blood pressure checks need to be carried out so that inmates in detention centers can avoid hypertension, which can be a risk factor for cardiovascular disease.
DIAGNOSTIC AND PROGNOSTIC VALUE OF CIRCULATING miRNAs AS NON-INVASIVE BIOMARKERS IN GLIOBLASTOMA MULTIFORME: A SYSTEMATIC REVIEW AND META-ANALYSIS Akas, Ignasius Dede Setyo; Seleky, Cherlyn; Febriani, Reka; Titaley, Christiana Rialine; Huwae, Laura Bianca Sylvia
MNJ (Malang Neurology Journal) Vol. 12 No. 2 (2026): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2026.012.02.14

Abstract

Background: Glioblastoma multiforme (GBM) is most prevalent and aggressive form of glioma, characterized by a high mortality rate and significant effect on patient's quality of life. The challenges in diagnosing, treating, and predicting prognosis of GBM highlight the need for more reliable biomarkers.  Promising characteristics as noninvasive biomarkers have been identified in microRNA (miRNAs) to their critical role in glioblastoma pathogenesis. Objective: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 standards guided implementation of this systematic review and meta-analysis examining diagnostic and prognostic relevance of microRNAs in GBM as non-invasive biomarkers. A total of 9 studies on diagnostic accuracy and 6 studies on prognostic analysis were included. Articles were identified through comprehensive searches in PubMed, EBSCO, and Wiley databases. Availability of diagnostic indicators such as area under curve (AUC), sensitivity, and specificity for miRNA-based diagnosis, along with survival measurements reported as hazard ratios (HRs) or mean survival outcomes, constituted main inclusion requirements for original studies. Results: In meta-analysis, circulating miRNAs achieved notable diagnostic performance, supported by sensitivity and specificity values of 0.86 and 0.92, respectively, along with AUC of 0.93. Subgroup analysis was then performed to assess consistency of accuracy based on ethnicity, sample source, dysregulation category, and miRNA profile mapping. Certain miRNAs also showed promise as prognosis markers as they are involved in glioblastoma progressivity. Conclusion: Circulating miRNAs demonstrate high accuracy as non-invasive biomarkers for GBM diagnosis and prognosis. Their role in glioblastoma progression suggests potential applications in more precise therapeutic approaches.
Co-Authors Akas, Ignasius Dede Setyo Bastian, Gustino Anjelo Bension, Johan Bruiyf Dyahnissa, Rahma Febriani, Reka Jusuf Leiwakabessy Noya, Farah Christina Rugebregt, Joanne Rugebregt, Joanne Marrijda Rusmin, Rusdiah Marhumi Safutra, Muhamad Sadam Saija, Alessandra Flowrence Seleky, Cherlyn Tentua, Vebiyanti Titaley, Christiana Rialine Wade Marlinda