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p-Index From 2021 - 2026
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All Journal International Journal of Health and Pharmaceutical (IJHP) Journal of Applied Agriculture, Health and Technology
Jackson Yang, John
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Agriculture, Biological Sciences & Forestry Computer Science & IT Medicine & Pharmacology Nursing Public Health

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Skrining Novel Prebiotik Selective Fermentation Initiator (SFI) Untuk Bakteri Probiotik Elektrogenik Kulit Adi, Prakoso; Mulyani, Rizka; Jackson Yang, John
Journal of Applied Agriculture, Health, and Technology Vol. 1 No. 1 (2022): June
Publisher : Sekolah Vokasi, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jaht.v1i1.261

Abstract

The ability of electrogenic bacteria to generate electricity has been widely reported. In some cases of bacteria, the electricity production comes from the bacterial fermentation process of SFI compounds by these bacteria. Later, the resulted electrons are transferred out from inside to extracellular recipient molecules. Among of these studies has shown the ability of gram-positive bacteria S. epidermidis ATCC 12228 in terms of SFI compounds utilization to increase bacterial electron production and its application in the medical field. Based on these studies, the discovery of new SFI compounds becomes interesting to be explored. In this study, a new SFI compound was screened from 24 different compounds. The screen was initiated by testing the ability of these compounds to increase the fermentation activity of S. epidermidis ATCC 12228 in a 96-well plate. Determination of SFI compound was carried out by checking the exclusivity of the compound to increase the fermentation activity of S. epidermidis ATCC 12228. The selected SFI compound was then tested for cytotoxicity against this bacterium and its ability to increase the electron production of S. epidermidis ATCC 12228 using a microbial fuel cell (MCF). This study was successfully demonstrated the non-toxic properties of p-coumaric acid, also the ability of this compound to increase the fermentation activity and electron production of S. epidermidis ATCC 12228. This research is expected to be the first step to find another novel SFI compounds that will be useful in certain fields in the future.
The Relationship Between Random Blood Glucose Levels and The Incidence of Diabetic Foot Ulcers Nunu Prihantini, Nur; Rahmawati, Fri; Angelita Permata Sitorus, Zefeilyne; Jackson Yang, John; Angreni, Frisca
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.615

Abstract

Diabetes mellitus is a global health challenge characterized by an ever-increasing number of cases annually. The most feared chronic complication of diabetes mellitus is diabetic foot ulcer (DFU), which significantly increases the risk of amputation and mortality rates. This study aims to analyze the relationship between random blood sugar (RBS) levels and the incidence of DFU in type 2 diabetes mellitus patients at Paragon Hospital, Citeureup 2026. The research method used is an analytical observational design with a cross-sectional approach. A total of 54 subjects meet the inclusion criteria out of 109 type 2 diabetes mellitus patients. Medical record data were statistically analyzed using the Chi-Square test. The results indicated that DFU patients were predominantly male (53.7%) and belonged to the 46-55 age group (38.9%). Clinical findings showed that the majority of research subjects (88.9%) had high random blood sugar levels (≥ 200 mg/dL). Statistical test results yielded a p-value of 0.000 (p < 0.05), indicating a significant relationship between high RBS levels and the incidence of DFU. Based on the result the concluded that uncontrolled RBS levels are a primary trigger for DFU. Chronic hyperglycemia triggers vascular and nerve damage, which inhibits the tissue healing process in the feet. Optimal control of RBS levels is essential as a preventive measure to avoid amputation complications in type 2 diabetes patients.
Co-Authors Adi, Prakoso Angelita Permata Sitorus, Zefeilyne Angreni, Frisca Mulyani, Rizka Prihantini, Nur Nunu Rahmawati, Fri