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Use of Medication in Outpatient Hypertension Patients Bulqiah, Andi; Suprapti, Budi; Ardiana, Shafira muti; Alsagaff, M. Yusuf; Suharjono
Window of Health : Jurnal Kesehatan VoL 6 No 2 (April 2023)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (623.497 KB) | DOI: 10.33096/woh.vi.66

Abstract

Hypertension is a major risk factor for cardiovascular disease, there are 1.13 billion people in the world suffering from hypertension. Hypertension should be given special consideration due to its impact on both the short and long term, one of which is by providing appropriate pharmacological therapy. The purpose of this study is to ascertain the pattern of medication use in hypertensive patients. The current study is a retrospective observational study that examines drug use patterns in hypertensive patients with or without associated disease. Using time-limited sampling techniques, the study sample is drawn from an electronic prescription of outpatient hypertension patients at Universitas Airlangga Surabaya Hospital (RSUA) in March 2021. According to the findings of this study, the most frequently prescribed antihypertensive medications were beta-blockers (29,66 %), ARB (27,51 %), CCB (26,17 %), aldosterone antagonists (6,72 %), loop diuretics (5,78 %), ACEi (3,98 %), and central α2 agonists (3,98 %) (0,14 % ). Antihypertension medications are prescribed singly or in combination. In hypertensive patients with co-morbidities, drugs other than antihypertensives will be prescribed to treat the co-morbidities. The most frequently prescribed non-antihypertensive drugs are antihyperlipidemia statin (45,1 %), platelet antiagregation (19,1%), and antiangina (13,8 %). The study concludes that antihypertension medications are used alone or in combination with up to five other antihypertensive medications, with the most common combination being three drugs in 45% of patients. Suggestions for this study are that it should be accompanied by direct patient identification to minimize the incidence of drug interactions and drug side effects in patients.
Analisis Kualitatif Kandungan Fukosantin ekstrak etanol 75%, Metanol 98% dan Metanol 75% dari Alga Coklat (Sargassum sp) Faika, Sitti; Herawati, Netti; Afni, Nur; Bulqiah, Andi
Indonesian Journal of Fundamental Sciences Vol 11, No 2 (2025)
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/ijfs.v11i2.78739

Abstract

Abstract. Meskipun antioksidan sintetik memiliki aktivitas antioksidan yang tinggi, antioksidan sintetik berpotensi menimbulkan efek samping yang merugikan kesehatan. Berdasarkan potensi keamanan dan khasiatnya, antioksidan alami layak dipertimbangkan sebagai sumber antioksidan dalam pengembangan produk baru. Fukosantin dalam Sargassum sp. memiliki bioaktivitas sebagai antioksidan, antiinflamasi, antikanker, antiobesitas, hepatoprotektif, antimalaria,  antidiabetik dan lain sebagainya. Tujuan peneliti ini adalah identifikasi awal fukosantin pada alga coklat, dengan menggunakan pelarut etanol 75%, metanol murni dan metanol 75%, menggunakan teknik maserasi  karena relatif cepat dan murah. Uji golongan untuk mengidentifikasi senyawa dilakukan menggunakan pereaksi Liebermann-Burchard, Serbuk Mg + HCl pekat, Dragendorff, Mayer, Wagner dan FeCl3 1%. Dimana  ekstrak etanol dan metanol alga coklat positif untuk golongan Terpenoid, alkaloid, dan fenolik, namun negatif untuk steroid dan flavonoid, yang mana menandakan didalam ekstrak terdapat Fukosantin yang juga dibuktikan dari hasil KLT (kromatografi lapis tipis) menunjukkan Rf 0,5. Keywords: alga coklat, fukosantin, Uji golong