Dwi Setio Purnomo
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Uji Kadar Timbal (Pb) pada Ikan Teri dan Cumi Kering yang Beredar di Pasar Sambu Medan secara Spektrofotometri Serapan Atom Hendri Faisal; Fitria Wati; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 2 No 1 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.10

Abstract

Anchovies and squid are some of the most abundant fishery resources in Indonesian waters. There is an increase in the concentration of heavy metals such as lead in marine waters which is caused by industrial waste, both solid and liquid waste, so that marine biota such as anchovies and squid accumulate these heavy metals. The very high level of heavy metal toxicity can have adverse effects on public health. The aim of this study was to determine the lead content and determine the number of levels in dried anchovies and dried squid circulating in Sambu Market, Medan City. This research used the atomic absorption spectrophotometric method at a wavelength of 283.8 nm. The results showed that dried anchovies and dried squid contained lead with the highest levelsin dried anchovies was 7.04 mg/kg and the levels in dried squid were 6.65 mg/kg. The metal content of lead in dried anchovies and dried squid has exceeded the maximum standard set by the Indonesian National Standard (SNI Number 7387 of 2009), namely 0.3 mg/kg in fish and their processed products, while 1.5 mg/kg in mollusks.
Analisa Vitamin C dan Evaluasi Sediaan Tablet Effervescent Campuran Ekstrak Etanol Biji Jambu Biji Merah dan Putih (Psidium guajava L.) Hendri Faisal; Suprianto; Nur Aisyah Pitri; Sri Handayani; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.40

Abstract

Effervescent tablets, CO2-producing tablets from the reaction of tablet constituents with their solvents. Red guava contains beta-carotene vitamin C is quite high, white guava is rich in vitamins, flavonoids, carotenoids, saponins, tannins, phenols, triterpenes, essential oils, fiber, and fatty acids. The study aimed at the comparison of vitamin C extract of red and white guava seeds (Psidium guavala. L). Powder evaluation includes flow time, angle of repose, compactibility. The evaluation of tablets included organoleptic, soluble time, weight uniformity, hardness, friability, pH, vitamin C content using UV spectrophotometry method. The results showed that the flow time test was 11.31-16 gram/second, the angle of repose was 33.02-34.92%; compactibility 7.59-16.9%; effervescent tablet preparation is round in shape, brown aroma, dark brown-brown color, slightly sweet taste, dissolving time 33.79- 89.53 seconds; hardness 4-5,4 kg; friability 0.04-0.9%; pH is close to neutral at pH 5.83-6.39; vitamin C content of red and white guava seeds were 37.86 mg/g and 42.32 mg/g, respectively. Red and white guava seed extract can be formulated into effervescent tablets and has vitamin C 0.19 – 0.28 mg/g
Optimasi Potensi Anti Escherichia coli dan Staphylococcus aureus Kombinasi Ekstrak Etil Asetat Allium cepa dan Allium sativum Suprianto; Dikari Harita; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 4 No 1 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i1.01

Abstract

Background: Natural antibiotics are often used as an alternative therapy. Microbial infections are the main cause of mortality and morbidity in developing countries, including Indonesia. Staphylococcus aureus and Escherichia coli are two microbes that are often used for testing natural antibiotics. Objective: This study aims to optimize the combination of shallot and white onion extracts to potentially inhibit bacterial growth and development. Method: This study used a randomised design method of a combination of onion and garlic extracts tested based on the inhibitory area response. Results: The combination of shallot and white onion ethyl acetate extracts showed activity as an inhibitor of bacterial growth and development. The combination of EBM and EBP provides an inhibitory response against Escherichia coli (X2) and Staphylococcus aureus (X3). Conclusion: Combining EBM and EBP can inhibit the growth and development of Escherichia coli and Staphylococcus aureus. The best combination as an inhibitor of growth and development was Escherichia coli (X2; 14.53 mm) and Staphylococcus aures (X3: 15.7 mm), respectively