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Literature Review: Characteristics Of Diabetic Foot Ulcer Patients Annisa Fathiya Muchlis; Andi Kartini Eka Yanti; Nasrah Anastasia Anjani
Jurnal EduHealth Vol. 15 No. 03 (2024): Jurnal EduHealt (September), Year 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetic foot begins with the presence of hyperglycemia in diabetic mellitus patients, causing neuropathy and vascular system disorders. There are several risk factors for the occurrence of diabetic foot ulcers, including gender, age and history of DM. This research method was carried out by literature review through the collection of various research journals and 11 samples of related research literature were obtained. The results of the study showed that the characteristics of diabetic foot ulcer patients were predominantly men with the highest age >60 years, the longest duration of suffering from DM was <10 years, and the highest degree of ulcers was degree 4. Age can be associated with the risk of developing diabetic foot ulcers
A Case Report of Malaria with Concurrent Dengue and Typhoid Fever Andi Kartini Eka Yanti; Andi Zul Tasyriq; Hendrian Chaniago
The Indonesian Journal of General Medicine Vol. 14 No. 1 (2025): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/a0e3x069

Abstract

Introduction: In Indonesia, malaria, dengue fever (DF), and typhoid fever are endemic infectious diseases that remain major public health concerns. Data from the Ministry of Health in 2025 show high incidence rates of these three diseases, especially in Papua, Bali, and urban areas, which increase the risk of coinfection and complicate diagnosis and treatment. Methods: A case is reported of an 18-year-old man presenting with high fever, headache, nausea, and thrombocytopenia. Initial serological and laboratory tests indicated dengue fever and typhoid infection. Routine monitoring and peripheral blood examination were performed and malaria co-infection was detected. Results: The patient's fever and platelets continued to decrease despite being given supportive therapy and antibiotics. Peripheral blood smear confirmed Plasmodium falciparum infection, prompting the addition of antimalarial therapy with dihydroartemisinin-piperaquine and primaquine. Following comprehensive treatment and close monitoring, the patient’s condition improved, with normalization of vital signs and increased platelet count. Conclusion: Coinfection of malaria, dengue fever, and typhoid in Indonesia is rare but requires special attention. Systematic diagnosis and intensive monitoring are essential for effective treatment and prevention of complications. Increased clinical awareness of possible multiple infections in febrile patients in endemic areas can improve prognosis and optimize patient management.
Peran Kontrol Tekanan Darah dalam Pencegahan Komplikasi Okular pada Pasien Hipertensi Asmaul Husnah; Andi Kartini Eka Yanti; Azizah Anoez
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i1.7538

Abstract

Hypertension is one of the main risk factors that can cause damage to target organs, including the eyes. One of the complications that often occur in hypertensive patients is hypertensive retinopathy, which is damage to retinal blood vessels due to a persistent increase in blood pressure. This damage can be progressive and asymptomatic in the early stages, so it often goes undetected until severe visual disturbances appear. This study aims to identify and analyze the role of blood pressure control in the prevention of ocular complications in hypertensive patients through a literature review. The method used is literature review by selecting national and international research articles published in 2021–2025 from the PubMed, ScienceDirect, Google Scholar, and Cochrane Library databases. Inclusion criteria include full-text articles, relevant research designs, and discussing the relationship between blood pressure control and ocular complications. The results of the study showed that uncontrolled blood pressure increased the risk of retinal damage, decreased ocular perfusion, and microvascular changes detected through funduscopy and Optical Coherence Tomography Angiography (OCTA) examinations. Some studies have concluded that stable blood pressure control, not just the average value of blood pressure, has a significant effect in preventing the progression of hypertensive retinopathy. In addition, regular eye exams have been proven to be able to detect retinal changes early, so that preventive interventions can be carried out in a timely manner. Thus, optimal blood pressure control, therapy adherence, healthy lifestyle education, and regular retinal examinations are effective strategies in preventing ocular complications and maintaining vision quality in hypertensive patients.
Analisis Hubungan Gula Darah Puasa dengan Tekanan Darah pada Pasien Hipertensi dengan Komorbid Diabetes Mellitus Nurmaya Azzahra; Andi Kartini Eka Yanti; Hidajah Hidajah
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i1.8148

Abstract

Hypertension and diabetes mellitus are two highly prevalent non-communicable diseases that often coexist as comorbidities, significantly increasing the risk of cardiovascular complications. The coexistence of these conditions accelerates the onset of atherosclerosis, diabetic nephropathy, and kidney failure, thereby requiring more comprehensive clinical management. One of the key parameters in diabetes management is fasting blood glucose (FBG), which reflects the balance of glucose metabolism after a fasting period. Chronic hyperglycemia is known to contribute to endothelial dysfunction, increased peripheral vascular resistance, and activation of the sympathetic nervous system and renin-angiotensin-aldosterone system, ultimately leading to elevated blood pressure. This study employed a systematic literature review approach, analyzing articles published between 2021 and 2025. Narrative synthesis was conducted across various study designs, including cross-sectional, cohort, and meta-analysis studies. The findings indicate that most studies support a significant association between FBG levels and blood pressure, although some reported varying results. Cohort studies provide stronger evidence that elevated FBG increases the risk of new-onset hypertension. Age, treatment adherence, and lifestyle factors were also identified as confounding variables influencing outcomes. Overall, the evidence highlights that glycemic control through FBG monitoring is essential in managing hypertension among diabetic patients. Multidisciplinary strategies, patient education, and strengthening of primary healthcare services are required to reduce cardiovascular risks. Longitudinal studies are recommended to deepen the understanding of the relationship between FBG and blood pressure and to reinforce the scientific basis for evidence-based clinical interventions.
Hubungan Tajam Penglihatan pada Penderita Hipertensi yang Mengalami Obesitas: (Literature Review) Nur Halifa Maharani Hairuddin; Andi Kartini Eka Yanti; Purnamanita Syawal
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i1.8407

Abstract

Hypertension, a global health issue, is increasingly prevalent and significantly contributes to morbidity and mortality. It often coexists with obesity, a key risk factor for hypertension and vascular complications. The combination of hypertension and obesity leads to metabolic changes, chronic inflammation, and oxidative stress that damage retinal blood vessels, directly affecting visual acuity. This literature review examines the relationship between hypertension, obesity, and visual acuity, analyzing 20 articles published between 2021 and 2025, sourced from PubMed, Google Scholar, and ScienceDirect. The study found a significant association between hypertension and obesity with decreased visual acuity. Obesity not only serves as a comorbidity but also as a mediator, worsening hypertension's effects through mechanisms like insulin resistance and endothelial dysfunction. Longitudinal studies indicate that visual impairment is progressive, while cross-sectional studies highlight its high prevalence in hypertensive obese populations. The review emphasizes the need for routine eye exams, blood pressure control, and weight management as preventive measures. In conclusion, hypertension and obesity together significantly increase the risk of visual impairment, necessitating a multidisciplinary approach to care and promoting preventive strategies to preserve eye health and enhance patients' quality of life.