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All Journal Socius: Social Sciences Research Journal Biosaintifika: Journal of Biology & Biology Education
Saputra, Muhammad Ragil
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media

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Topical Ointment Anredera cordifolia Leaves Ethanolic Extract-Loaded Nanochitosan Promotes Wound Healing in Hyperglycemic Rat Alfatinnisa, Zalfa; Andriyan, Mohammad Wahyu; Saputra, Muhammad Ragil; Astuti, Endah Puji; Sunarno, Sunarno; Isdadiyanto, Sri; Subagio, Agus; Jaya, La Ode Irman
Biosaintifika: Journal of Biology & Biology Education Vol. 16 No. 1 (2024): April 2024
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v15i1.1842

Abstract

Wound healing in hyperglycemia patients is still a challenge in the medical field. Bioactive compounds of binahong leaf extract can support the wound healing process. Nanoencapsulation of the extract can avoid oxidation and optimize drug delivery to target tissues. This study aimed to analyze the effect of nanochitosan encapsulated binahong extract ointment (NEBE/Oint) on the percentage of wound healing, angiogenesis, collagen density, and epithelial thickness in hyperglycemic rats. This study used 80 mg/kg streptozotocin-induced hyperglycemia rats injured in the back area. Rats were divided into P0 (0,9% NaCl), P1 (10% povidone-iodine ointment (PI/Oint)), P2 (10% NEBE/Oint), P3 (20% NEBE/Oint), P4 (30% NEBE/Oint). Phytochemical screening of binahong leaves extract showed positive results for flavonoids, alkaloids, saponins, and tannins. NEBE particle size was 169 nm with a size distribution of 0.2 and a zeta potential value of -40,2 mV. The results showed NEBE ointment had a significant effect when compared with negative control on wound healing hyperglycemic rats. The conclusion is that nanochitosan drug delivery has the potential as an alternative wound treatment. The novelty of this study is the use of nanochitosan to accelerate wound healing in hyperglycemic rats. The results of this study are expected to become a reference for new wound-healing methods in the medical field.
Menjunjung Kebersamaan Dalam Perbedaan: Studi Moderasi Beragama di Indonesia Perspektif Tafsir Maudhu’i Nasher, Abdurrahman; Malihah, Nadia Rosikhoh; Fauziah, Salma; Luthfiyyah, Nayla Desiyana; Santoso, Muhammad Iqbal Firdaus; Saputra, Muhammad Ragil; Fauzi, Asep Muhammad; Muhyi, Asep Abdul; Chodijah, Siti
Socius: Jurnal Penelitian Ilmu-Ilmu Sosial Vol 2, No 11 (2025): June, 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15568986

Abstract

This research article aims to understand religious moderation in the perspective of the interpretation of the Qur’an thematically/maudhu’I from various classical, modern, and contemporary interpretation books and to find out the existence of religious moderation in Indonesia. The method used is qualitative research by taking data from literature studies from books, scriptures, and journals that have a high H-index and citation rate based on the Publish or Perish application. In this study, it was found that there are five verses of the Qur’an that contain words that are in line with moderation, namely wasathan, wustha, awsath, and wasathan which have the meaning of middle, fair, good, and most important. The real contribution that can be made from this research is as a reference in implementing religious moderation from the interpretation perspective and can be socialized to the Indonesian people. This research focuses on the realm of interpretation related to religious moderation and to add to the intellectual treasury of Islam in facing the challenges of religious life and religiosity to welcome tolerance and peace among religious adherents.
Co-Authors Agus Subagio Alfatinnisa, Zalfa Andriyan, Mohammad Wahyu Endah Puji Astuti, Endah Puji Fauzi, Asep Muhammad Fauziah, Salma Jaya, La Ode Irman Luthfiyyah, Nayla Desiyana Malihah, Nadia Rosikhoh Muhyi, Asep Abdul Nasher, Abdurrahman Santoso, Muhammad Iqbal Firdaus Siti Chodijah Sri Isdadiyanto Sunarno Sunarno