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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Jurnal Health Sains Media Dermato-Venereologica Indonesiana
Rusetiyanti, Nurwestu
Unknown Affiliation
Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Anti-Retroviral Treatment in dr. Sardjito Central General Hospital Yogyakarta Aquaira, Labitta Pachira; Febriana, Sri Awalia; Rusetiyanti, Nurwestu
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 3 (2024): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.3.2024.162-167

Abstract

Background: Adverse cutaneous drug reactions (ACDRs) affect 2-3% of hospitalized patients globally, wherein approximately 2% (1 in 1,000 cases) accounted for a severe form of cutaneous drug reactions. Out of all dermatologic diagnoses recorded by HIV patients, eight-point twenty-five percent of patients feature ACDRs, indicating that these patients are 100 times more inclined to develop unfortunate, severe reactions to anti-retroviral treatment. Therefore, there is an urgency in identifying the prevalence of ACDRs in HIV patients taking anti-retroviral treatment. Purpose: The aim of this study is to calculate the prevalence of anti-retroviral drug-induced ACDRs in HIV-positive patients in Central General Hospital, in the time period of January 2015 to December 2017. Methods: This study analyzed inpatient and outpatient medical records from January 2015 to December 2017 in the Dermatology and Venereology Department of dr. Sardjito Central General Hospital, which recorded ART-induced ACDRs manifestations. Result: This study revealed a prevalence of 0.095% of ACDRs as a result of ART administration, with 1.5% HIV-positive patients affected by ACDRs in response to ART medication. A m sex ratio of 2:1 with an average age of 30.4 ± 5.94 years old was found. The most predominant type of ACDR found in HIV-positive patients receiving ART was maculopapular rash (46.7%), while the most common type of drug within the ART regimen to cause such ACDR was Nevirapine (25.8%). Discussion: Nevirapine was the most common type of causative drug, for monotherapy (22.6%) and polytherapy (25.8%).
HIV in Elderly Patient Fatmala, Galuh Dyah; Claramita, Mora; Rusetiyanti, Nurwestu
Review of Primary Care Practice and Education Vol 7, No 1 (2024): January
Publisher : Faculty of Medicine, Public Health, and Nursing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/rpcpe.93047

Abstract

The patient is 66-year-old men from a small village in the foot of the Merapi volcano, Java Island, Indonesia. He is a husband and a father of three children with three granddaughters. He describes his life as a happy snack fruit farmer, adores living with his caring wife and enjoying role as a mosque priest in his village. But all are disrupted as his health condition has worsened in the past year. Previously, he has been hospitalized twice with the final diagnosis of chronic obstructive pulmonary disease; the tuberculosis has been ruled out by acid fast bacillus test since he also presenting with significant weight loss. Otherwise, he also has multiple visits to dermatologist due to itchy all over his body which is not improving with primary health center (puskesmas) medication. For his blurry eyes, he has been referred by his general practitioner to the ophthalmologist to be suspected with glaucoma and have lanatoprost medication for his eyes daily. He is also having diagnosis of lumbago with sciatica by neurologist since both of his legs are always sore and tingling. All of his outpatient visits and hospitalizations are covered by government health coverage in the same hospital as he has been referred by puskesmas.
Clinical Improvement of Patients With Complications of Exfoliativa Dermatitis: A Case Report Christabella, Nathania; Primas Adjie, Sugih; Rusetiyanti, Nurwestu; Anggorowati, Nungki; Raisa, Husna
Jurnal Health Sains Vol. 5 No. 10 (2024): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i10.1384

Abstract

Exfoliative dermatitis or erythroderma is a severe skin inflammatory syndrome, characterized by erythema and desquamation more than 90% of the body surface area. Previous study shown erythroderma incidence was 83 people in 2011 to 2014. Incidence of erythroderma in Portugal 9.4 cases per year, with the predominance age of 41 to 61 years. The most common etiology of erythroderma is psoriasis and dermatitis. A woman Mrs. T, 55 years old, came to emergency room Rajawali Citra General Hospital Bantul on 5 September 2023 with complaints of abdominal pain, frequent vomit, cough and itchy and dry skin on the face, upper limbs and lower limbs. Patient has erythroderma medical history since a year ago. On dermatological examination, the facial showed patch erythema with scales on left suprasilia and nasales, the upper and lower limbs showed xerotic. This patient was diagnosed with erythroderma with improvements. Patient was treated with Loratadine 10 mg tablets once a day orally and Desoximethasone oint twice a day. Erythroderma treatment depends on its underlying disease. The main therapy is using petrolatum, emollient or low-potency topical steroid to maintaince skin barrier function and reduce inflammatory. Antihistamines can be used to relieve pruritus and as antianxiety agent. A well combination drugs therapy shows clinical improvement on erythroderma performance.
Koilositosis: Efek Sitopatik dari Infeksi Human Papilloma Virus Cut Aigia Wulan Safitri; Rusetiyanti, Nurwestu; Arkania, Nabila
Media Dermato-Venereologica Indonesiana Vol 52 No 4 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i4.572

Abstract

Koilositosis merupakan perubahan sitopatologis khas akibat infeksi human papillomavirus (HPV) pada sel epitel skuamosa anogenital yang ditandai dengan pembesaran inti, vakuolisasi sitoplasma, dan batas inti yang tidak teratur. HPV merupakan virus deoxyribo nucleic acid (DNA) yang menyebabkan berbagai penyakit, mulai dari kutil anogenital hingga kanker serviks. Aktivitas protein onkogenik HPV, seperti E6 dan E7, memainkan peran penting dalam patogenesis koilositosis. Koilositosis sering ditemukan pada lesi prakanker, terutama cervical intraepithelial neoplasia (CIN). Deteksi koilositosis merupakan temuan sitopatologis penting, berfungsi sebagai petunjuk diagnosis infeksi HPV, penanda pada skrining kanker serviks, dan dasar strategi manajemen infeksi HPV. Diperlukan pengetahuan dasar terkait proses infeksi HPV serta nilai diagnostik dari temuan koilosit sehingga pemantauan dan pendekatan berbasis risiko dalam manajemen infeksi HPV untuk mencegah progresi lesi menjadi kanker invasif dapat terlaksana dengan baik. 
Co-Authors Aquaira, Labitta Pachira Arkania, Nabila Christabella, Nathania Cut Aigia Wulan Safitri Fatmala, Galuh Dyah Febriana, Sri Awalia Mora Claramita Nungki Anggorowati Primas Adjie, Sugih Raisa, Husna