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Losartan sebagai Regimen Penurun Serum Asam Urat pada Penderita Gout dengan Hipertensi: Florence Pribadi; Ronald Torang Marsahala Panggabean; Angelarita Djami Raga; Ellysia Yuvena Maheswari; Berlian Ester Wakas; Almer Fathoni Syahda; Lola Adriani; Kevin Luke
Unram Medical Journal Vol 11 No 3 (2022): volume 11 no 3
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i3.739

Abstract

Asam urat (AU) merupakan produk akhir dari metabolisme purin yang terdistribusi pada plasma dan cairan synovial. Solubilitas AU pada air sangat rendah, sehingga pada konsentrasi 6.8 mg/dL dapat membentuk kristal, yaitu monosodium urat. Kristal yang mengendap di sendi dapat memicu proses inflammasi yang disebut dengan gout artritis (GA). Penatalaksanaan GA yang tidak optimal menyebabkan penurunan kualitas hidup yang signifikan. Losartan merupakan obat hipertensi yang bekerja dengan memblokade reseptor Angiotensin I, sekaligus memiliki efek menurunkan kadar AU. Losartan diduga menghambat transporter URAT1 pada tubulus ginjal, sehingga menganggu reabsorbsi AU dan menyebabkan efek urikosurik. Tinjauan ini akan membahas potensi Losartan sebagai regimen terapi penurun AU pada penderita gout dengan hipertensi.
Upaya Pencegahan Demensia pada Lansia Melalui Intervensi Edukasi dalam Bentuk Seminar Interaktif Novian Budi Santoso; Hanna Tabita Hasianna Silitonga; Ronald Torang Marsahala Panggabean; Hebert Adrianto; Cindy Clara Sari; Najmul Laila; Nurul Illahi Muhammad Risha; Etha Rambung; Elizabeth Sulastri Nugraheni; Ni Njoman Juliasih
SAFARI :Jurnal Pengabdian Masyarakat Indonesia Vol. 5 No. 3 (2025): Juli : SAFARI :Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/safari.v5i3.2852

Abstract

Physical and mental changes in the elderly can have an impact on the health of the elderly. Dementia is one of the main health problems experienced by the elderly, characterized by decreased cognitive function that impacts quality of life and independence. Lack of public understanding of early detection, treatment, and prevention of dementia increases the risk of delayed treatment and worsens the condition of the elderly. This community service aims to increase knowledge and awareness of dementia through interactive seminars for the elderly and their families at GKI Sepanjang Sidoarjo. The results of the interactive seminar showed that the percentage of correct answers in the post-test increased by 13.14% from the pre-test. As many as five out of 10 questions with correct answers amounted to more than 50% of the total respondents. Judging from the answers obtained, program participants were not familiar with examples of cognitive functions and the definition of Hoarding Syndrome. At the end of this activity, there was an increase in participants' understanding of improving the health of the elderly, but there were still questions that participants could not answer. In conclusion, this activity succeeded in increasing health literacy related to dementia among the elderly and their families at GKI Sepanjang Sidoarjo, but other educational methods or media are needed to further increase the knowledge of the elderly regarding dementia.
Education of Cardiovascular Disease in the Elderly through Health Seminars and Health Corner Silitonga, Hanna Tabita Hasianna; Panggabean, Ronald Torang Marsahala; Rambung, Etha; Adrianto, Hebert; Sheyoputri, Rytney Electra; Xena, Leora Esther
Poltanesa Vol 25 No 1 (2024): June 2024
Publisher : P3KM Politeknik Pertanian Negeri Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51967/tanesa.v25i1.3032

Abstract

Advanced age or elderly refers to individuals who have reached the age of 60 and above. According to data from the National Socioeconomic Survey in March 2020, there is a total of 10.48%, consisting of 51.81% elderly women and 48.19% elderly men. The elderly population undergoes the aging process, making them at a higher risk of degenerative diseases. According to Basic Health Research in 2013, the most common diseases among the elderly are hypertension (57.6%), arthritis (51.9%), stroke (46.1%), dental and oral problems (19.1%), chronic obstructive pulmonary disease (8.6%), and diabetes mellitus (4.8%). Hypertension can lead to other disorders, such as cardiovascular disease. Cardiovascular diseases have a high mortality rate and can be caused by various factors, such as diabetes mellitus and obesity resulting from an unhealthy lifestyle. Therefore, through education on cardiovascular diseases and the formation of elderly cadres and health corners, efforts to prevent cardiovascular diseases in the elderly are expected to be optimally implemented. The main target of this program is the congregation of the Indonesian Christian Church (GKI) in Sepanjang Sidoarjo, Taman District, Sidoarjo Regency. Activities include pre-tests and post-tests related to cardiovascular diseases in the elderly, health seminars, and the establishment of health corners. The results of this activity show that the respondents' knowledge level, assessed through questionnaires, had an average pre-test score of 12.52 and a post-test score of 14.71, indicating a significant change with a p-value < 0.001 meeting the significant level of 95%.
Hubungan Antara Stres Dan Risiko Kardiovaskular Berdasar Jakvas Scoring System: Studi Pada Ojek Online Di Surabaya Handari, Saskia Dyah; Ginting, Adhitya; Panggabean, Ronald Torang Marsahala; Adrianto, Hebert; Suryadarma, Antonius Yansen; Christine, Catarina Lilian; Dion, Aldy; Jefri, Wilhelmus; Putri, Firda Aulia; Damayanti, Ni Nyoman Rere; Yasa, Oka Suputra
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 11 (2025): Volume 12 Nomor 11
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i11.20686

Abstract

Stres kerja merupakan salah satu faktor risiko utama yang dapat memengaruhi kesehatan kardiovaskular. Salah satu profesi pekerjaan yang berisiko stres adalah pengemudi ojek online. Penelitian memiliki tujuan untuk melihat hubungan tingkat stres dengan skor JAKVAS. Penelitian ini adalah penelitian observasional analitik dengan pendekatan cross sectional. Responden adalah 75 orang sopir transportasi online laki-laki yang mengendarai sepeda motor dari 5 wilayah Surabaya, yang diambil dengan accidental sampling. Pengukuran tingkat stress menggunakan kuesioner Perceived Stress Scale (PSS). Pengukuran risiko kardiovaskular menggunakan Jakarta Cardiovascular Score (JAKVAS). Data dianalisis statistik dengan menggunakan program jamovi, menggunakan statistik deskriptif dan uji chi square. Hasil penelitian didapatkan skor JAKVAS terbanyak adalah kategori high risk (40%),  mayoritas responden memiliki tingkat stress berat (37,3%), tidak terdapat hubungan yang bermakna secara statistik antara tingkat stres dan skor JAKVAS (χ² = 4,396; df = 4; p = 0,355). Meskipun hubungan keduanya tidak signifikan, tingginya proporsi responden dengan risiko kardiovaskular tinggi menegaskan perlunya skrining rutin pada profesi dengan beban kerja tinggi seperti pengemudi ojek online.