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Correlation Between Chemotherapy-Induced Nausea and Vomiting with Quality of Life in Patients with Ovarian Cancer at Dr. Cipto Mangunkusumo Hospital Madjid, Veinardi; Calvin, David; Purwoto, Gatot; Utami, Tofan Widya; Anggraeni, Tricia Dewi; Vidiawati, Dhanasari; Winarto, Hariyono
Makara Journal of Health Research
Publisher : UI Scholars Hub

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Abstract

Introduction: Nausea and vomiting (NV) remain as side effects of chemotherapy, which has a detrimental effect on patients’ quality of life (QOL) and treatment adherence. This study aimed to determine the effect of chemotherapy-induced NV (CINV) on the QOL of patients with ovarian cancer treated with chemotherapy at Dr. Cipto Mangunkusumo Hospital (CMH). Methods: We conducted a cross-sectional study in patients with ovarian cancer receiving first-line chemotherapy regimens of carboplatin and paclitaxel. The European Organisation for Research and Treatment helped translate the Quality-of-Life Questionnaire-OV28 (QLQ-OV28) into Indonesian and tested it in a preliminary study. The approved Indonesian version of the QLQ-OV28, with the Quality-of-Life Questionnaire-C30 (QLQ-C30), was then used to evaluate QOL before and 1 week after chemotherapy. Results: Several symptom scales increased, whereas function scales decreased. Moreover, 72.5% had an increase in the NV symptom scale, whereas 67.5% had a decrease in patients’ scale after chemotherapy. CINV had a significant partial effect on reducing QOL (p = 0.047 and y = 12.208–0.432). Conclusions: CINV has a significant influence on lowering the QOL of patients with ovarian cancer undergoing first-line chemotherapy regimens with carboplatin and paclitaxel in CMH.
An Implementation of Patient Safety Program at Hospital Royal Prima Medan in 2021 Calvin, David; Ginting, Chrismis Novalinda; Nasution, Sri Wahyuni
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6395

Abstract

This research aims to know and analyze the implementation of the Patient Safety program and the factors that influence it at the Royal Prima Hospital Medan in 2021. This research is a mixed methods research that is a combination of qualitative and quantitative research. The research informants consisted of 1 person from the hospital health committee, 1 head of the inpatient ward, and 4 implementing nurses in the inpatient ward. The population is all implementing nurses in the inpatient rooms as many as 319 people. the sample was taken using the Taro Yamane formula for as many as 76 people. Data collection techniques through interviews, questionnaires, and documentation. Data analysis methods consist of qualitative analysis with descriptive methods and quantitatively using univariate, bivariate, and multivariate analysis using p multiple linear regression equation. The results of the study that the implementation of the patient safety program at the Royal Prima Hospital Medan in 2021 is quite good; there is an influence of the knowledge, attitude, workload, and supervision of the head of the room on the implementation of the Patient Safety program at the Royal Prima Hospital Medan in 2021.