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All Journal JIK- JURNAL ILMU KESEHATAN Jurnal Prima Medika Sains
Sitompul, Mutiara Rolika Putri
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Health Professions Medicine & Pharmacology Nursing Public Health

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Analysis of the potential of memelong leaves (Philodendron giganteum) as an antioxidant and antimicrobial Silitonga, Martha; Sitompul, Mutiara Rolika Putri; Gulo, Agnes; Anggeria, Elis
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.5552

Abstract

Ornamental plants are plants whose main function is to decorate. Many ornamental plants have benefits, one of which is the Philodendron plant. It is important to know the benefits of antioxidants and antimicrobials that ornamental plants have and can be used to improve health. The research aimed to determine the potential of Memelong (Philodendron giganteum) as an antioxidant and antimicrobial. The research carried out was empirical research at the FKKGIK UNPRI Laboratory for 1 month. The samples used were all Memelong leaves. Memelong leaf extract is made by maceration. Next, carry out phytochemical tests including alkaloid testing, flavonoid content testing, saponin testing, testing for the presence of tannins, and testing for triterpenoids and steroids. The antioxidant activity test was carried out using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The antimicrobial activity test was carried out using the paper disc diffusion method. Data analysis using univariate presented in the form of tables and graphs descriptively. The results of this study have potential as antioxidants based on antioxidant tests using the DPPH method with sample concentrations of 400 ppm 14%, 600 ppm 16%, 800 ppm 19%, and 1000 ppm 27%, but the results are still smaller when compared to the vitamin C test results. However, in the antibacterial activity test on Memelong leaf extract, there was no inhibition zone in the 25% formulation, an average of 0.50%, an average of 0.75%, an average of 0, the K(+) was found to be an average of 18,85 diameter of inhibition zone. The research conclusion is that the leaves of Memelong are proven to contain antioxidants.
Quick Of Blood Terhadap Penurunan Kadar Ureum Pada Pasien Gagal Ginjal Kronik Yang Sedang Menjalani Terapi Hemodialisa Sihombing, Melisa; Marbun, Yesa Meliana; Sitompul, Mutiara Rolika Putri; Ambarita, Sarah Emma Tiovani; Halawa, Kurniawati; Kaban, Karmila Br
JIK-JURNAL ILMU KESEHATAN Vol 9, No 1 (2025): JIK-April Volume 9 Nomor 1 Tahun 2025
Publisher : UNIVERSITAS ALIFAH PADANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33757/jik.v9i1.1262

Abstract

Gagal Ginjal Kronik (GGK) adalah suatu proses fisiopatologi yang disebabkan berbagai faktor, yang mengakibatkan penurunan fungsi ginjal secara bertahap dan pada akhirnya menjadi penyakit gagal ginjal. Hemodialisis merupakan suatu prosedur penyaringan darah menggunakan mesin khusus guna menopang kehidupan pasien penyakit GGK. Ureum merupakan hasil dari metabolit utama yang berasal dari pergantian protein jaringan dan protein makanan didalam tubuh. Quick of blood adalah volume darah (ml/menit) yang melewati mesin hemodialisis dalam satu menit. Tercapainya efektivitas dalam terapi hemodialisis tergantung pada pemenuhan volume hemodialisis yang diberikan kepada pasien. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh  Quick of blood terhadap penurunan kadar ureum pasien gagal ginjal kronik yang menjalani hemodialisa. Penelitian ini menggunakan jenis penelitian kuantitatif dengan pendekatan cross-sectional. Sampel dalam penelitian ini adalah  91 responden dengan teknik pengambilan purposive sampling. Penelitian ini dilaksanakan di RSU Royal Prima Medan. Teknik analisa data penelitian ini menggunakan uji  Wilcoxon didapatkan bahwa p – value  0,000 menunjukkan adanya pengaruh  dalam penentuan Quick of blood terhadap penurunan kadar ureum pasien gagal ginjal kronik yang menjalani terapi hemodialisa.
Co-Authors Agnes Gulo Ambarita, Sarah Emma Tiovani Br Kaban, Karmila Elis Anggeria Halawa, Kurniawati Marbun, Yesa Meliana Sihombing, Melisa Silitonga, Martha