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All Journal Jurnal Riset Biologi dan Aplikasinya Indonesian Journal of Business, Accounting and Management
Amira, Siti
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Environmental Science Immunology & microbiology Medicine & Pharmacology

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Morpho-histological Study of the Rat Spleen Post-Induction of Sodium Nitrite and Acorus calamus L. Rhizome Ethanolic Extract Amira, Siti; Febriani, Husnarika; Syukriah, Syukriah; Nur Faizah, Ulinnuha
Jurnal Riset Biologi dan Aplikasinya Vol. 5 No. 2 (2023)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jrba.v5n2.p89-97

Abstract

Sodium nitrite (NaNO2) is one of the most inorganic salts and is often used in processed meat products. Long-term consumption of sodium nitrite has been reported to cause of oxidative stress and spleen histological changes. Therefore, anti-oxidative effects are needed from natural ingredients such as Acorus calamus L. The study aims to determine the effect of A.calamus L. rhizome extract on anatomical structure and histological changes in the rat spleen induced with NaNO2. We used a completely randomized design with twenty-five male rats divided into 5 groups. Negative control (NC) was given 0.5% CMC for 40 days; positive control (PC) on days 1-15 was given NaNO2 (50 mg/kg BW); on days 16-30 given (50 mg/kg BW) NaNO2 + 0.5% CMC and on days 31-40 given 0,5% carboxy methyl cellulose (CMC). Treatment 1 (T1), Treatment 2 (T2), and Treatment 3 (T3) on days 1-15 were given NaNO2 doses of 50 mg; and; on days 16-30, groups T1, T2, and T3 were given NaNO2 + extract with each predetermined dose (250 mg/kg BW for T1, 500 mg/kg BW for T2, and 750 mg/kg BW for T3). For days 31-40 groups T1, T2, and T3 were given extracts with each predetermined dose. Results revealed that the extract of the A. calamus L. rhizome affects weight, length, and width of the spleen (P<0.05); and bleeding lesions; while having no noticeable effect (P<0.05) and having a noticeable effect on the area of the white pulp (P<0.05). Administration of ethanol extract of A. calamus L. at a dose of 250 mg/kg BW has an impact on improving spleen length; a dose of 500 mg/kg BW has an impact on the weight and length of the spleen; and a dose of 750 mg / kg BW has an impact on improving spleen length, but the size variation is still in the normal category. While extracts at doses of 250 and 500 mg/kg BW have a repair impact on tissue shrinkage in damaged white pulp. 
Does profitability affect stock prices? Empirical evidence from the plastic and packaging sub-sector of the Indonesia Stock Exchange Apandi, Aden; Mustafa, Yusufi Arif; Kamilah, Siti; Amira, Siti
Indonesian Journal of Business, Accounting and Management Vol. 7 No. 2 (2024)
Publisher : Sekolah Tinggi Ilmu Ekonomi Indonesia Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36406/ijbam.v7i2.9

Abstract

This study aims to analyze the effect of profitability ratios on stock prices of manufacturing companies in the plastic and packaging sub-sector listed on the Indonesia Stock Exchange (IDX) during 2019–2023. The profitability ratios examined are Return on Assets (ROA), Return on Equity (ROE), and Net Profit Margin (NPM). Using purposive sampling, five companies were selected, and secondary data were obtained from their annual financial reports. Data analysis was conducted through descriptive statistics, classical assumption tests, and panel data regression with the Random Effect Model (REM). The findings reveal that ROA and ROE have no significant effect on stock prices, while NPM has a positive and significant impact. These results indicate that investors tend to consider sales-based profitability rather than asset and equity efficiency when valuing stock prices in the plastic and packaging sub-sector. This study provides implications for investors, company management, and regulators in evaluating financial performance, formulating profitability strategies, and supporting capital market stability in Indonesia. Article Information:Received 7/10/2024 / Revised 11/12/2024 / Accepted 12/18/2024 / Online First 12/25/2024
Co-Authors Apandi, Aden Husnarika Febriani, Husnarika Mustafa, Yusufi Arif Nur Faizah, Ulinnuha Siti Kamilah, Siti Syukriah Syukriah, Syukriah