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All Journal Bioma : Berkala Ilmiah Biologi Jurnal Riset Biologi dan Aplikasinya Indonesian Journal of Business, Accounting and Management Lombok Medical Journal
Amira, Siti
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Public Health

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Morpho-histological Study of the Rat Spleen Post-Induction of Sodium Nitrite and Acorus calamus L. Rhizome Ethanolic Extract Amira, Siti; Febriani, Husnarika; Syukriah, Syukriah; Nur Faizah, Ulinnuha
Jurnal Riset Biologi dan Aplikasinya Vol. 5 No. 2 (2023)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jrba.v5n2.p89-97

Abstract

Sodium nitrite (NaNO2) is one of the most inorganic salts and is often used in processed meat products. Long-term consumption of sodium nitrite has been reported to cause of oxidative stress and spleen histological changes. Therefore, anti-oxidative effects are needed from natural ingredients such as Acorus calamus L. The study aims to determine the effect of A.calamus L. rhizome extract on anatomical structure and histological changes in the rat spleen induced with NaNO2. We used a completely randomized design with twenty-five male rats divided into 5 groups. Negative control (NC) was given 0.5% CMC for 40 days; positive control (PC) on days 1-15 was given NaNO2 (50 mg/kg BW); on days 16-30 given (50 mg/kg BW) NaNO2 + 0.5% CMC and on days 31-40 given 0,5% carboxy methyl cellulose (CMC). Treatment 1 (T1), Treatment 2 (T2), and Treatment 3 (T3) on days 1-15 were given NaNO2 doses of 50 mg; and; on days 16-30, groups T1, T2, and T3 were given NaNO2 + extract with each predetermined dose (250 mg/kg BW for T1, 500 mg/kg BW for T2, and 750 mg/kg BW for T3). For days 31-40 groups T1, T2, and T3 were given extracts with each predetermined dose. Results revealed that the extract of the A. calamus L. rhizome affects weight, length, and width of the spleen (P<0.05); and bleeding lesions; while having no noticeable effect (P<0.05) and having a noticeable effect on the area of the white pulp (P<0.05). Administration of ethanol extract of A. calamus L. at a dose of 250 mg/kg BW has an impact on improving spleen length; a dose of 500 mg/kg BW has an impact on the weight and length of the spleen; and a dose of 750 mg / kg BW has an impact on improving spleen length, but the size variation is still in the normal category. While extracts at doses of 250 and 500 mg/kg BW have a repair impact on tissue shrinkage in damaged white pulp. 
Does profitability affect stock prices? Empirical evidence from the plastic and packaging sub-sector of the Indonesia Stock Exchange Apandi, Aden; Mustafa, Yusufi Arif; Kamilah, Siti; Amira, Siti
Indonesian Journal of Business, Accounting and Management Vol. 7 No. 2 (2024)
Publisher : Sekolah Tinggi Ilmu Ekonomi Indonesia Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36406/ijbam.v7i2.9

Abstract

This study aims to analyze the effect of profitability ratios on stock prices of manufacturing companies in the plastic and packaging sub-sector listed on the Indonesia Stock Exchange (IDX) during 2019–2023. The profitability ratios examined are Return on Assets (ROA), Return on Equity (ROE), and Net Profit Margin (NPM). Using purposive sampling, five companies were selected, and secondary data were obtained from their annual financial reports. Data analysis was conducted through descriptive statistics, classical assumption tests, and panel data regression with the Random Effect Model (REM). The findings reveal that ROA and ROE have no significant effect on stock prices, while NPM has a positive and significant impact. These results indicate that investors tend to consider sales-based profitability rather than asset and equity efficiency when valuing stock prices in the plastic and packaging sub-sector. This study provides implications for investors, company management, and regulators in evaluating financial performance, formulating profitability strategies, and supporting capital market stability in Indonesia. Article Information:Received 7/10/2024 / Revised 11/12/2024 / Accepted 12/18/2024 / Online First 12/25/2024
Studi Kandungan Logam Berat Besi (Fe) pada Air dan Ikan di Tambak Medan Belawan Sumatera Utara Syukriah, Syukriah; Fauziansyah, Hidayat; Amira, Siti
Bioma : Berkala Ilmiah Biologi Vol. 26, No 1, Tahun 2024
Publisher : Departemen Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/bioma.2024.58929

Abstract

Kecamatan Medan Belawan merupakan lokasi industri perikanan terbesar ke tiga di Kota Medan. Kualitas air yang buruk pada Kecamatan Medan Belawan membuat industri perikanan diwilayah ini menghadapi sejumlah permasalahan terhadap kualitas ikan. Penelitian ini bertujuan untuk mengetahui kadar logam berat besi (Fe) pada air tambak, hasil budidaya perikanan dan Bioconcentration factor logam berat besi (Fe) pada ikan dan udang di Medan Belawan. Penelitian ini menggunakan metode Purposive Sampling dengan pengambilan sampel di tiga titik yaitu tambak budidaya ikan nila, udang dan ikan mujair. Pengujian logam berat besi dilakukan dengan menggunakan Atomic Absorption Spectophotometry (AAS) kemudian analisis kandungan logam berat di setiap sampel akan dibandingkan dengan PP No. 22 Tahun 2021. Hasil pengujian kandungan logam besi pada air  tambak melebihi standar baku mutu. Kandungan logam besi (Fe) pada air tambak 1, 2 dan 3 masing-masing sebesar 0,51, 0,93 dan 1,19 mg/L. Kandungan kadar besi (Fe) pada daging ikan nila 8,36 mg/kg, pada udang sebesar 10,0 mg/kg dan mujair 6,24 mg/kg. Hasil ini menunjukkan kandungan total ion Fe berada jauh di atas standar batas aman adanya kontaminan Fe dalam pangan berdasarkan FAO/WHO (2011) sebesar 0,8 mg/kg.
The Impact of Solanum lasiocarpum Extract on Hyperglycemic Rats' Blood Profiles, Glucose Levels, Liver, and Kidney Syukriah; Augustin Ningrum, Nurlian; Amira, Siti
Lombok Medical Journal Vol. 5 No. 2 (2026): Lombok Medical Journal (InPress)
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/gq0svd83

Abstract

Hyperglycemia is an increase in blood glucose levels that leads to diabetes mellitus. Diabetes mellitus caused by insulin resistance and impaired insulin secretion. Eggplant (Solanum lasiocarpum) is an herbal plant used as a traditional remedy for diabetes mellitus. This study aims to determine the effect of Eggplant fruit extract (S. lasiocarpum) on blood glucose, blood profile, SGPT, SGOT, creatinine, and ureum levels in diabetic rats. This study used a completely randomized design with six groups (G1: normal control, G2: diabetes control, G3: metformin control, G4: extract dose 200 mg/kg BW; G5: extract dose 300 mg/kg BW; and G6: extract dose 400 mg/kg BW. Measurement of  SGPT, SGOT, Urea, and Creatinine levels using a spectrophotometer. Data analysis uses one-way ANOVA and Duncan at a significance level of 0.05. Statistical analysis revealed a significant difference (p<0.05) between the control group and extract therapy in blood glucose, blood profile tests, SGPT, SGOT, creatinine, and urem. The optimal dose of S. lasiocarpum fruit extract to reduce the effects caused by diabetes was  400 mg/kg BW.
Co-Authors Apandi, Aden Augustin Ningrum, Nurlian Fauziansyah, Hidayat Husnarika Febriani, Husnarika Mustafa, Yusufi Arif Nur Faizah, Ulinnuha Siti Kamilah, Siti Syukriah Syukriah Syukriah, Syukriah