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All Journal Journal of Pharmaceutical and Sciences. Servitium Smart Journal
Palandi, Reky Royke
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Aplikasi Budidaya Itik Petelur Berbahan Pakan Lokal pada Kelompok Tani Nyiur Melambai Untu, Sonny Denny; Palandi, Reky Royke; Rumondor, Fadly Steven Jefry; Montolalu, Friska Mery; Kanter, Jabes; Karauwan, Ferdy; Korua, Sammy Rommy Novie
Servitium Smart Journal Vol 3 No 1 (2024): Servitium Smart Journal
Publisher : Universitas Klabat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31154/servitium.v3i1.33

Abstract

This service aims to help the Nyiur Melambai Farmers Group in Tomohon City in increasing the productivity of laying ducks through the application of locally made feed. The main problems faced by partners are the high price of commercial feed, low knowledge in making alternative feed, and suboptimal business management. The solutions implemented include training in processing feed from local ingredients, introduction to appropriate technology, and cage renovation. The results of this activity show an increase in feed production, a reduction in feed costs, and an increase in the capacity of partners in business management. This service contributes to increasing partner income and strengthening the sustainability of the laying duck business.
Optimalisasi Produksi dan Pemasaran Sabun Organik Eco Enzyme di Kota Tomohon Palandi, Reky Royke; Pareta, Douglas N; Kanter, Jabes; Korua, Sammy Rommy Novie
Servitium Smart Journal Vol 3 No 1 (2024): Servitium Smart Journal
Publisher : Universitas Klabat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31154/servitium.v3i1.34

Abstract

This community service aims to optimize the production and marketing of organic soap made from eco enzymes in Tumatangtang Satu Village, Tomohon City. This organic soap is produced through the use of eco enzymes from abundant fruit and vegetable waste in the area. Although the business has been running, production is still limited to a home scale, and marketing is not optimal. The program includes the procurement of new equipment, production skills training, and the utilization of digital platforms for marketing. The results of this activity are expected to increase production up to 150 soaps per day and increase market reach through digital marketing.
Uji aktivitas antioksidan ekstrak etanol daun benalu Helixanthera cylindrica (Jack) Danser pada tumbuhan kelor (Moringa oleifera) dengan metode 2,2-diphenyl-1-picrylhydrazyl Potalangi, Nerni Olvi; Palandi, Reky Royke; Manoppo, Amalia J.; Tewu, Tewsi M.; Kanter, Jabes Wolter; Sambou, Christel Nataniel
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.626

Abstract

Free radicals can originate from within the human body as a result of metabolic processes from chemical reactions in the body, as well as from external sources or the environment, including emissions from motor vehicles, air pollution from factories, industrial chemicals, food and beverage substances, cigarette smoke, radiation, and sunlight. Antioxidants are components that can prevent cells or molecules from being oxidised by donating electrons or hydrogen atoms to free radicals. The impact of the reactivity of free radical compounds can result in cell or tissue damage, degenerative diseases, and even cancer. One of the parasites on the moringa plant, namely Helixanthera cylindrica (Jack) Danser, contains secondary metabolite compounds such as alkaloids, flavonoids, and saponins. This research aimed to determine whether the leaves of the Helixanthera cylindrica (Jack) Danser mistletoe have antioxidant activity using the 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) method. The research method is a laboratory experiment with five concentrations and three repetitions. Subsequently, the antioxidant activity testing is conducted qualitatively using the DPPH method at a wavelength of 517 nm and utilising a Spectrophotometer UV-Vis. Based on the results of the antioxidant test, the extract of Helixanthera cylindrica (Jack) Danser leaves has extreme activity with an IC50 value of 28.74 ppm. In contrast, the comparison, vitamin C has an IC50 value of 1.57 ppm. The regression equation for the concentration of the mistletoe is y=0.3344x + 40.389 with an R2 value of 0.9726, and Vitamin C shows y=4.4065x + 43.079 with an R² value of 0.9677. It can be concluded that the leaves of Helixanthera cylindrica (Jack) Danser on the Moringa oleifera plant have extreme antioxidant activity.
Aktivitas Antimikobakteri serta Penentuan MIC–MBC Ekstrak Etanol Daun Clerodendrum minahassae terhadap Mycobacterium smegmatis Palandi, Reky Royke; Lengkey , Yessie K.; Maarisit , Wilmar; Sumangando , Adolfina; Potalangi , Nerny A.; Karauwan , Ferdy A.; Tulandi , Selvana S.; Untu , Sonny D.; Pareta , Douglas N
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1242

Abstract

Tuberculosis remains a major global health challenge, particularly due to the increasing emergence of drug-resistant strains, highlighting the need for new antimycobacterial agents from natural sources. Clerodendrum minahassae, a medicinal plant traditionally used in North Sulawesi, has demonstrated antibacterial activity; however, its antimycobacterial potential has not been previously explored. This study aimed to evaluate the antimycobacterial activity of the ethanolic leaf extract of C. minahassae against Mycobacterium smegmatis as a surrogate model and to estimate its minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The extract was tested at concentrations of 5, 7.5, and 10 µg/disc using the disc diffusion method. Inhibition zone diameters increased in a concentration-dependent manner, ranging from 9.40 ± 0.52 mm to 10.60 ± 0.92 mm. Quantitative analysis using Bloomfield-based linear regression revealed a strong dose–response relationship (R² = 0.9926), from which MIC and MBC values of 0.63 µg/disc and 2.52 µg/disc were estimated, respectively. These findings indicate that the ethanolic extract of C. minahassae exhibits measurable inhibitory and bactericidal activity against M. smegmatis at relatively low concentrations. While this study represents an exploratory screening, the results support the potential of C. minahassae as a source of bioactive compounds with antimycobacterial relevance. Further investigations involving fractionation, compound identification, toxicity assessment, and validation against pathogenic Mycobacterium tuberculosis strains are warranted.  
Co-Authors Fadly Steven Jefry Rumondor Friska Mery Montolalu Jabes Wolter Kanter Karauwan , Ferdy A. Karauwan, Ferdy Korua, Sammy Rommy Novie Lengkey , Yessie K. Maarisit , Wilmar Manoppo, Amalia J. Pareta , Douglas N Pareta, Douglas N Potalangi , Nerny A. Potalangi, Nerni Olvi Sambou, Christel N. Sonny Untu Sumangando , Adolfina Tewu, Tewsi M. Tulandi , Selvana S. Untu , Sonny D.