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All Journal Jurnal Sains Farmasi dan Kesehatan Jurnal Riset Multidisiplin Edukasi
Annur tasya alfiati
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Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary Other

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Formulasi Dan Evaluasi Sediaan Tablet Ibuprofen Menggunakan Berbagai Bahan Pengikat Dalam Metode Granulasi Basah Nor Aida; Nafach Olya Warasky; Laila manada; Annur tasya alfiati; Sofi agustia putri
Jurnal Sains Farmasi Dan Kesehatan Vol. 2 No. 2 (2024): September - Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v2i2.1787

Abstract

The aim of this research is to conduct a study on the Formulation and Evaluation of Ibuprofen Tablet Preparations Using Various Binder Materials in the Wet Granulation Method. The method used in this research is a systematic literature review. The results of this study indicate that research on ibuprofen tablet formulations shows that the physical quality of tablets is greatly influenced by the selection of binders, disintegrants, lubricants, and other excipients. The appropriate binder ensures that the tablet has the correct hardness and can disintegrate properly, allowing the active ingredient to be effectively absorbed by the body. The right disintegrant is also crucial for speeding up the tablet's disintegration time, while the lubricant functions to reduce friction during tablet manufacturing, although it must be used in a balanced amount to avoid hindering dissolution. Furthermore, factors such as the moisture content of the granules and the physical properties of the granules also play a role in determining the tablet's quality. Studies show that the right formulation, such as a combination of CMC-Na, sorbitol, and amylum solani binders, can improve dissolution and bioavailability, leading to better therapeutic effectiveness. Overall, the selection of the appropriate materials and proportions in the formulation of ibuprofen tablets is crucial to produce tablets with high bioavailability and optimal therapeutic effects..
MANAJEMEN PRODUK KEMBALIAN DI ERA PERSAINGAN GLOBAL: OPTIMALISASI PROSES RECALL, RETUR, DAN SELF-INSPECTION DALAM RANTAI PASOK MODERN Annur Tasya Alfiati; Riska Hidayah; Nor Latifah
Jurnal Riset Multidisiplin Edukasi Vol. 2 No. 7 (2025): Jurnal Riset Multidisiplin Edukasi (Edisi Juli 2025)
Publisher : PT. Hasba Edukasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71282/jurmie.v2i7.629

Abstract

Product return management, including recall, return, and self-inspection processes, is a crucial aspect in maintaining product quality and consumer satisfaction in global supply chains. Globalization has introduced new challenges in managing more complex product returns, requiring more advanced strategies and technologies to ensure efficiency and effectiveness in these processes. Technologies such as AI, machine learning, and blockchain provide solutions for optimizing recall, return, and self-inspection management by accelerating issue detection and improving transparency. Collaboration between suppliers, producers, and distributors also plays a significant role in identifying problems early. This article provides an overview of the importance of effective product return management and how technology and collaboration can assist companies in addressing challenges in global supply chains.
Co-Authors Laila manada Nafach Olya Warasky Nor Aida Nor Latifah Riska Hidayah Sofi agustia putri