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REVIEW: PENGARUH PERBEDAAN EKSIPIEN BINDER PADA TABLET PARACETAMOL TERHADAP WAKTU HANCUR DAN PELEPASAN OBAT Iqbal Nurwahid; Alfia Mujahra; Muhammad Zairullah; Riska Hidayah; Helsy Indarwati; Nor Latifah
Jurnal Cakrawala Ilmiah Vol. 4 No. 3: Nopember 2024
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aims to evaluate and compare the effectiveness of natural and synthetic binders in paracetamol tablet formulation, focusing on sweet potato starch, pregelatinized cassava, and pectin as natural binders, as well as synthetic binders commonly used in the pharmaceutical industry. The method used in this study is a literature review, by collecting, analyzing, and synthesizing various relevant previous research results regarding the effect of binders on the physical properties of tablets and drug dissolution rates. Based on the literature analysis, it was found that natural binders, such as pregelatinized starch and pectin, showed comparable or even better results in several parameters, such as disintegration and drug release, compared to synthetic binders. Pregelatinized starch, in particular, showed a faster dissolution rate, while pectin gave good results in terms of tablet hardness and friability. In addition, natural binders are more economical and environmentally friendly than synthetic materials.
MANAJEMEN PRODUK KEMBALIAN DI ERA PERSAINGAN GLOBAL: OPTIMALISASI PROSES RECALL, RETUR, DAN SELF-INSPECTION DALAM RANTAI PASOK MODERN Annur Tasya Alfiati; Riska Hidayah; Nor Latifah
Jurnal Riset Multidisiplin Edukasi Vol. 2 No. 7 (2025): Jurnal Riset Multidisiplin Edukasi (Edisi Juli 2025)
Publisher : PT. Hasba Edukasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71282/jurmie.v2i7.629

Abstract

Product return management, including recall, return, and self-inspection processes, is a crucial aspect in maintaining product quality and consumer satisfaction in global supply chains. Globalization has introduced new challenges in managing more complex product returns, requiring more advanced strategies and technologies to ensure efficiency and effectiveness in these processes. Technologies such as AI, machine learning, and blockchain provide solutions for optimizing recall, return, and self-inspection management by accelerating issue detection and improving transparency. Collaboration between suppliers, producers, and distributors also plays a significant role in identifying problems early. This article provides an overview of the importance of effective product return management and how technology and collaboration can assist companies in addressing challenges in global supply chains.
Literature Review : Skrining Fitokimia Pada Berbagai Tanaman Obat Sebagai Sumber Senyawa Bioaktif Nadia Safitri; Riska Hidayah; Nita Triadisti
Jurnal Riset Multidisiplin Edukasi Vol. 2 No. 7 (2025): Jurnal Riset Multidisiplin Edukasi (Edisi Juli 2025)
Publisher : PT. Hasba Edukasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71282/jurmie.v2i7.773

Abstract

Phytochemical screening is a crucial preliminary step in identifying secondary metabolites from medicinal plants that serve as potential bioactive compounds for the development of traditional and modern medicines. This review summarizes findings from 25 national and international journals that investigated various plant sources, including leaves, flowers, seeds, fruits, stems, and even microalgae. The most commonly analyzed compounds include flavonoids, alkaloids, tannins, saponins, steroids, triterpenoids, polyphenols, glycosides, and anthraquinones. The results indicate that flavonoids and tannins are the most frequently detected metabolites, both of which are known for their antioxidant, antimicrobial, anti-inflammatory, and wound-healing properties. Variations in metabolite content among plants are influenced by species, plant parts used, extraction methods, and the choice of solvents, with ethanol being the predominant solvent. Several studies also complemented the screening with biological activity assays, such as DPPH antioxidant testing, antibacterial assays, and wound-healing studies, further supporting the therapeutic potential of these compounds. This review highlights the importance of phytochemical screening as a scientific foundation for the development of phytopharmaceuticals and the utilization of Indonesia’s rich biodiversity.