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Wenilia, Rosita
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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KARDIOMIOPATI HIPERTROFI: SEBUAH TINJAUAN PUSTAKA Nurhaliza, Siti; Hazaa, Saskia Safarinaa; Nur Rifa'i, Ahmad; Fadila, Amila; Nugraha, Kadek Nandita; Syamsuddin, Muhammad Zaim Muflih; Wenilia, Rosita; Yahya, Najla Aulia; Putra, Rifky Sandya Rakadi; Kadarisma, Sofia; Safira, Siska Dwi
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.36755

Abstract

Kardiomiopati hipertrofi (HCM) adalah kelainan genetik miosit jantung yang mengakibatkan hipertrofi ventrikel kiri, fibrosis dan hiperkontraktilitas jantung. Kelainan ini diduga akibat mutasi gen sarkomer dominan autosomal. dan merupakan penyebab kematian mendadak paling sering pada usia muda. Berdasarkan data ekokardiografi yang berasal dari Amerika Serikat teridentifikasi sebanyak 0.2% dari keseluruhan populasi menderita kardimiopati hipertrofi. Penelitian ini menggunakan pendekatan tinjauan literatur dengan mengumpulkan data dari basis data online seperti PubMed, ScienceDirect, MDPI, dan Google Scholar. Tinjauan literatur ini secara komprehensif membahas definisi, etiologi, epidemiologi, faktor risiko, patofisiologi, diagnosis, tatalaksana, komplikasi dan prognosis kardiomiopati hipertrofi.
Hypothyroid and Heart Disease Wenilia, Rosita
Jurnal Medika Hutama Vol. 6 No. 01 Oktober (2024): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Thyroid hormones, particularly T3 (triiodothyronine) and T4 (thyroxine), play a crucial role in regulating metabolism, growth, and cardiovascular function. Thyroid gland dysfunctions, such as hypothyroidism and hyperthyroidism, can have significant impacts on the cardiovascular system. Hypothyroidism is associated with reduced cardiac output, diastolic hypertension, and an increased risk of coronary heart disease (CHD), while hyperthyroidism can elevate heart rate and blood volume, potentially leading to cardiomyopathy. Epidemiological studies show that the prevalence of hypothyroidism is higher than hyperthyroidism, but it is often undiagnosed. Treatment of hypothyroidism involves the use of levothyroxine, aiming to normalize TSH and T4 levels through gradual titration. Special attention is required in treating patients with heart conditions to prevent complications such as myxedema coma. Therefore, early detection, prevention, and treatment of hypothyroidism are essential to reduce cardiovascular morbidity and mortality risks.
Co-Authors Fadila, Amila Hazaa, Saskia Safarinaa Kadarisma, Sofia Nugraha, Kadek Nandita Nur Rifa'i, Ahmad Putra, Rifky Sandya Rakadi Safira, Siska Dwi Siti Nurhaliza Syamsuddin, Muhammad Zaim Muflih Yahya, Najla Aulia