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All Journal Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Buletin Farmatera Indonesian Journal of Cardiology JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Ahmad Dahlan Medical Journal Jurnal Pandu Husada

Ahmad Handayani

Universitas Muhammadiyah Sumatera Utara

Author-ID : 806232

Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Sistem Konduksi Jantung Ahmad Handayani
Buletin Farmatera Vol 2, No 3 (2017)
Publisher : Universitas Muhammadiyah Sumatera Utara

Abstrak Pemahaman ilmu dasar kedokteran sangat penting bagi seorang klinisi. Aritmia merupakan masalah kardiovaskular yang cukup sering dijumpai dan menyulitkan. Pemahaman tentang dasar elektrofisiologi, cara kerja elektrokardiografi, dan mekanisme terjadinya aritmia jantung merupakan modal dasar seorang dokter untuk memiliki pendekatan yang logis dalam diagnosa dan terapi pada pasien dengan kondisi aritmia. Pemahaman sistem konduksi jantung setidaknya membutuhkan pemahaman tentang dua hal yakni dasar kelistrikan jantung mencakup potensial aksi sel otot jantung dan sel pacu jantung dan konsep pembentukan dan penjalaran impuls melalui sistem konduksi jantung. Tulisan ini bertujuan memberikan gambaran umum yang ringkas dan mendasar tentang sistem konduksi jantung. Kata kunci: aritmia, kelistrikan, konduksi, jantung Abstract Understanding the basic science of medicine is very important for a clinician. Arrhythmias are a quite common and complicated cardiovascular problem. Understanding of the electrophysiological basis, the workings of electrocardiography, and the mechanism of cardiac arrhythmia are the doctors' basic requirement for having a logical approach to diagnosis and therapy in patients with arrhythmia. Understanding the cardiac conduction system requires at least an understanding of two things: the base of the heart's electricity includes the potential action of heart muscle and pacemaker cells and the concept of impulse formation and propagation through the cardiac conduction system. This paper aims to provide a concise and basic overview of the cardiac conduction system. Keywords: arrhythmia, electricity, conduction, heart

PREDICTORS OF IN-HOSPITAL LENGTH OF STAY IN NSTEMI PATIENTS Ahmad Handayani; Andika Sitepu; Faisal Habib
Buletin Farmatera Vol 4, No 3 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

As our population grows older, the rate of NSTEMI patients is rising. Risk stratification is an important process for patients with Non-ST Elevation Myocardial Infarction (NSTEMI). Global Registry of Acute Coronary Events (GRACE) scores in the best to predict mortality and myocardial infarction in NSTEMI Patients. On the other hand, NSTEMI Patients trends to be older with more co-morbidity. In this scenario, we need to predict the length of stay as it correlates with the patient's prognostic and cost. This study aims to analyze factors influencing the in-hospital length of stay in survivor NSTEMI Patients in four different hospitals (Adam Malik Medan National General Hospital, Pirngadi Medan General Hospital, Grandmed Lubuk Pakam General Hospital, and Aceh Tamiang Public General Hospital). This was an observational study with prospective design conducted on 44 patients in four different hospitals from March to May 2017. We only included the patients that discharged alive from the. hospital Statistical analysis was performed to assess the routine clinical and laboratory variables relations with the length of stay. Prolong length of stay was defined as more than 5 days. As mentioned in the previous study, older age, heart failure will prolong the length of stay. The limitations of this study were we didn't analyze the effect of revascularization, the co-morbidities, and the method of patient’s payment. We should use GRACE and TIMI risk score routinely, optimizing therapy for heart failure and giving special attention to elderly patients in NSTEMI Patients.Keywords: NSTEMI, GRACE, Length of Stay

Premature Ventricular Complexes: Diagnose, Evaluation, and Management Handayani, Ahmad; Lubis, Anggia Chairuddin
Buletin Farmatera Vol 7, No 1 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i1.9684

Premature ventricular complexes (PVCs) are arrhythmias due to abnormal impulse formation in the ventricles. The incidence is detected as much as 1% on standard electrocardiographic (ECG) examination. The aim of this literature review is to explain the diagnosis, evaluation, and management of PVC. The diagnosis of PVC is determined from the symptoms and evidence from the ECG recording. Symptoms may include a faster heartbeat sensation, chest discomfort, skipped beat, and intermittenly strong heartbeat. Evidence of PVC is established by regular ECG recordings or Holter. A 12-ECG can help determine the location of source. PVC evaluation includes determine the dangerousity, the next examination step, the treatment options, and whether ablation is needed. Managements include medical therapy and catheter ablation. Catheter ablation is performed where treatment is unsatisfactory or if the PVC causing life threathening arrhythmia or cardiomyopathy. PVC is considered dangerous if the underlying disease is found in the form of cardiac structural abnormalities, ischemic heart disease or other arrhythmic disorders, more than 2000 PVC is found in 24 hours, complex morphology, different morphology, increased with exercise, PVC with non-outflow tract form, with short coupling interval, and with a wider QRS duration The incidence of VVC that is considered to be able to induce cardiomyopathy is from 10-26%. PVC requires a structured and systematic diagnosis and evaluation step to determine the appropriate treatment.

HUBUNGAN POLIMORFISME GEN ANGIOTENSIN CONVERTING ENZYME DENGAN PERBAIKAN FRAKSI EJEKSI VENTRIKEL KIRI PADA PASIEN GAGAL JANTUNG KRONIK Handayani, Ahmad; Thristy, Isra; Andina, Meizly
Buletin Farmatera Vol 6, No 2 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i2.5549

Angiotensin-converting enzyme (ACE) is a circulating and membrane-bound enzyme in the renin-angiotensin system. Polymorphism is the presence of two or more alleles at a locus in a population. In patients with heart failure with impaired systolic function, the RAA system is activated. One of the main therapies in heart failure is the administration of angiotensin-converting enzyme blockers. This study aims to examine the relationship between angiotensin-converting enzyme gene polymorphisms with improvement in left ventricular ejection fraction (FEVK).This research is a prospective observational study using a convenient sampling technique, carried out at Mitra Medika Hospital Bandar Klippa, Deli Serdang. The number of samples in the study was 37 people. Each patient was examined for initial echocardiography and at least 1 month after treatment when clinical improvement was seen. All patients received treatment according to the standard guidelines for the management of chronic heart failure according to the European Society of Cardiology (ESC)/Indonesian Cardiovascular Specialist Doctors Association (PERKI). The majority of research subjects were male as much as 81% and the average age of the patients was 56 years. ACE gene polymorphism was dominated by gene II as much as 57%. The average FEVK value in the first measurement was 25.8% and in the second measurement, it increased to 34.4%. There was a significant change between FEVK I measurements by an average of 25% to 34% in the next measurement (p 0.05). In the analysis of the relationship, it was seen that the ACE gene polymorphism did not affect the improvement of the FEVK value.Treatment of chronic heart failure with a decrease in ejection fraction was seen to have a significant effect in increasing FEVK. There is no relationship between angiotensin-converting enzyme gene polymorphisms on response to therapy in patients with chronic heart failure in this study.

Pengaruh Membaca Al-Qur’an Terhadap Penurunan Tekanan Darah Pada Lansia Hipertensi Di UPT Pelayanan Sosial Lanjut Usia Binjai Rizki, Muhammad; Siregar, Maulana; Handayani, Ahmad; Sutysna, Hendra
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.24411

Abstract: Reading the Qur'an is a form of dhikr and as a meditation in positive benefits for the body. Hypertension is a condition when blood pressure in tFaculty of Medicine he blood vessels increases chronically at 140/90 mmHg. The prevalence rate in Binjai City in 2016 was found to be 366 hypertension patients. Therapy to read the Qur'an harmoniously and carefully can improve biochemistry in the body that lowers blood pressure. This study aims to determine the effect of reading the Qur'an on reducing blood pressure in the elderly with hypertension at the Binjai Elderly Social Service Unit. This study uses a type of quantitative research with a quasi-experimental method with a non-randommized pre test-post test control group design. Based on the results of the study, it was found that there was an average difference between the intervention and control groups, where the systolic mean was 143.25 and diastolic 88.37, while the systolic and diastolic mean of the control group were 150.43 and 94.75. This is because the verses of the Qur'an read by hypertensive patients can activate endorphins naturally, thereby increasing feelings of relaxation and lowering blood pressure. It was found that the P value in the final systolic variable was 0.034 which means that there was a mean difference between the final systolic in the intervention group and the control group because P was 0.05, while the P value in the final diastolic variable was 0.001 which can be concluded that there is a significant mean difference between the final systolic of the intervention group and the control group because of P 0.05. Based on this study, it was found that the majority of hypertension is found in women and 60-74 years old. There was a difference in average blood pressure in the intervention and control groups.

Co-Authors Abdul Gafar Parinduri Abdullah Afif Siregar Annisa AZZUHRA PERMATA KHAIRA BATUBARA, HEPPY JELITA SARI DINDA ETIKA SURY ELIZABETH ADINDA PUTRI HARAHAP Faisal Habib FAWWAZ, ADITYA ACHMAD GARBIE SYAHLY AGUNG HENDRA SUTYSNA Indrawan Sani, Riyanda Isra Thristy Kaban, Kartika Kartika Kaban Lubis, Anggia Chairuddin Marwan Nasri Mayfa, Rara Khairania Meizly Andina, Meizly Muhammad Rizki Mukhtar, Zulfikri Nasri, Marwan Nasution, Ria Wenny Purwoko, Firda Syakirina Putri, Sheila Dhiene RITONGA, MISTAR Sheila Dhiene Putri Siregar, Abdullah Afif SIREGAR, CINDY OKTAVIA Siregar, Maulana Sitepu, Andika TRESNA ADI PRAYOGA WIRDANI FADHILA Yelly Nursakinah Zulfikri Mukhtar

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