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All Journal PEDAMAS (Pengabdian Kepada Masyarakat) Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara
Manik, Umi Chairani
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences Other

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Determination of Total Flavonoid of Ethanol Extract of Pegagan Leaves (Centella asiatica (L.) Urb) Using Maceration and Soxhletation Methods Wahyudi, Muhammad; Manik, Umi Chairani; Ridwanto, Ridwanto; Daulay, Anny Sartika; Rahmadani, Rahmadani
Indonesian Journal of Science and Pharmacy Vol. 2 No. 1 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v2i1.63

Abstract

A study was conducted to determine the total flavonoid content of ethanol extract of pegagan leaves (Centella asiatica (L.) Urb) using maceration and soxhletation methods. The study began with the preparation of pegagan leaf simplicia and its characterization, preparation of ethanol extract by maceration and soxhletation, phytochemical screening and determination of total flavonoid content of ethanol extract of pegagan leaves using visible spectrophotometry method. The results of phytochemical screening of ethanol extract of pegagan leaves indicated the presence of alkaloid, flavonoid, saponin, tannin, steroid/triterpenoid and glycoside compounds. The results of determining the total flavonoid content in ethanol solvent extract by maceration were 31.6416±0.1534 mgQE/g and ethanol solvent extract by soxhletation were 20.832±0.0514 mgQE/g. Extraction of pegagan leaves by maceration method was more effective than soxhletation method.
PEMBERDAYAAN USAHA MIKRO PEMBUATAN JAMU JAHE INSTAN DI DESA KLAMBIR V KAMPUNG Afriati, Nelsi; Mutiara, Widya; Azhari, Putri Mita; Wijaya, Azhari; Pratiwi, Nur Aisyah; Manik, Umi Chairani; Syahputri, Hindri
PEDAMAS (PENGABDIAN KEPADA MASYARAKAT) Vol. 2 No. 06 (2024): NOVEMBER 2024
Publisher : MEDIA INOVASI PENDIDIKAN DAN PUBLIKASI

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Abstract

Tanaman Obat Keluarga (TOGA) pada hakikatnya adalah tanaman berkhasiat yang ditanam di lahan pekarangan yang dikelola oleh keluarga. Ditanam dalam rangka memenuhi keperluan keluarga akan obat-obatan tradisional yang dapat dibuat sendiri. Tanaman obat ini kemudian dapat dimanfaatkan sebagai obat tradisional yang dapat dibuat dengan mudah. Dalam Kuliah Kerja Nyata (KKN) ini kami berinisiatif untuk membuat Tanaman Obat Keluarga (TOGA) agar dapat mempermudah warga Desa Tanjung Raja dalam memanfaatkan nya. Penanaman di lakukan untuk meningkatkan kesadaran terkait pemanfaatan lahan. Penanaman dilakukan di lahan depan Kantor Kepala Desa agar warga dapat dengan mudah menjaga, dan memanfaatkan tanaman tersebut. Sasaran kegiatan ini adalah seluruh masyarakat di Desa Tanjung Raja, Kecamatan STM Hulu, Kabupaten Deli Serdang. Dengan adanya ini, diharapkan warga bisa lebih kreatif dan inovatif. Dengan adanya Tanaman Obat Keluarga (TOGA) ini kami berharap warga bisa memanfaatkan dan merawatnya dengan baik.
Retrospective Study Of Vitamin Purchases During The Pandemic In UMI FARMA Pharmacy Manik, Umi Chairani; Nasution, Muhammad Amin; Octania, Adelia Dwi
Indonesian Journal of Science and Pharmacy Vol. 1 No. 2 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i2.29

Abstract

In early 2020, the world was shocked by the outbreak of a new pneumonia that started in Wuhan, China, and then spread rapidly to more than 190 countries and territories. This outbreak was named coronavirus disease 2019 (COVID-19), which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SA RS-CoV-2). The spread of this disease has had a broad social and economic impact.The COVID-19 pandemic that has occurred since March 2020 has affected all aspects of life. The aim of the research is to determine the purchase of vitamins during the pandemic in July–December 2021 at the UMI FARMA Pharmacy. This research was conducted retrospectively. Data collection was obtained from recording several vitamin products purchased by patients. Data was obtained from the sales and purchases book at the UMI FARMA Pharmacy. The targeted output is purchasing vitamins during the pandemic in July–December 2021.
Edukasi Bahaya Narkoba sebagai Upaya Peningkatan Pemahaman Warga Binaan Lembaga Pemasyarakatan Tanjung Gusta Medan Manik, Umi Chairani; Utami, Dinda Sari
Jurnal Bakti Nusantara Vol. 1 No. 3 (2024): Jurnal Bakti Nusantara
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/jbn.v1i3.53

Abstract

Penyalahgunaan narkotika, psikotropika, dan obat terlarang (narkoba) masih menjadi masalah yang belum teratasi hingga saat ini. Banyaknya kasus pecandu narkoba yang sudah direhabilitasi di Lembaga Pemasyarakatan, kembali menggunakan narkoba setelah bebas. Salah satu penyebabnya adalah kurangnya pemahaman yang komprehensif tentang bahaya narkoba. Kegiatan pengabdian masyarakat ini bertujuan mengedukasi warga binaan Lembaga Pemasyarakatan Kelas I Tanjung Gusta Medan sebagai upaya meningkatkan pemahaman warga binaan tentang bahaya narkoba. Metode yang digunakan dalam edukasi adalah ceramah dan diskusi. Tahapan kegiatan meliputi persiapan, pelaksanaan, dan evaluasi. Hasil tes akhir menunjukkan terjadi peningkatan pemahaman warga binaan tentang bahaya narkoba sebesar 92,19% setelah dilakukan edukasi. Kegiatan edukasi kepada warga binaan terbukti memberikan dampak positif dan diharapkan setelah keluar dari lembaga pemasyarakatan pecandu narkoba tidak lagi menggunakan narkoba.
Phytochemical Screening and Antibacterial Activity of Jatropha multifida Leaf Extract Against Pseudomonas aeruginosa Manik, Umi Chairani; Rahmadani, Rahmadani
Indonesian Journal of Science and Pharmacy Vol. 3 No. 2 (2025): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i2.133

Abstract

The increasing prevalence of antibiotic-resistant bacteria has encouraged the exploration of alternative antibacterial agents derived from medicinal plants. Jatropha multifida L., commonly known as the Bethadine plant, has been traditionally used for treating infections and wounds due to its bioactive phytochemical compounds. This study aimed to evaluate the antibacterial activity of Jatropha multifida leaf extract against Pseudomonas aeruginosa and to identify the presence of secondary metabolites through phytochemical screening. The study employed an experimental laboratory design. Jatropha multifida leaves were processed into simplicia powder and extracted using the maceration method. Phytochemical screening was performed to detect the presence of alkaloids, flavonoids, saponins, steroids/triterpenoids, and tannins. The antibacterial activity of the extract was tested against Pseudomonas aeruginosa using the agar disc diffusion (Kirby–Bauer) method at concentrations of 10%, 20%, 30%, 40%, and 50%. Chloramphenicol and dimethyl sulfoxide (DMSO) were used as positive and negative controls, respectively. Phytochemical screening revealed the presence of several secondary metabolites, including alkaloids, flavonoids, saponins, steroids/triterpenoids, and tannins in the Jatropha multifida leaf extract. The antibacterial assay demonstrated that the extract inhibited the growth of Pseudomonas aeruginosa, as indicated by the formation of inhibition zones around the discs. The diameter of the inhibition zones increased with increasing extract concentration, indicating a concentration-dependent antibacterial effect. Jatropha multifida leaf extract possesses antibacterial activity against Pseudomonas aeruginosa, which may be attributed to the presence of bioactive secondary metabolites. These findings suggest that the plant has potential as a natural source of antibacterial agents. Further studies are recommended to isolate and characterize the active compounds responsible for the antibacterial activity.
Co-Authors Afriati, Nelsi Anny Sartika Daulay Azhari, Putri Mita Dinda Sari Utami Hindri Syahputri Muhammad Amin Nasution Muhammad Wahyudi Mutiara, Widya Octania, Adelia Dwi Pratiwi, Nur Aisyah Rahmadani Rahmadani Ridwanto Ridwanto Wijaya, Azhari