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Crude Drugs Standardization, Total Flavonoid and Phenolic Content Profile, and Antimicrobial Activity of Red Ginger and Lemongrass Combination Puspitasari, Adinda; Hamad, Alwani; Hartanti, Dwi
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 2 (2024): December 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i2.2008

Baturraden people use a combination of red ginger rhizomes and lemongrass leaves for the treatment of masuk angin. This study aims to evaluate the quality profile of red ginger and lemongrass crude drug, total flavonoid content (TPC), total phenolic content (TFC), and the antimicrobial activities of their combination water extracts. The quality of both crude drugs was standardized to Indonesian Herbal Pharmacopeia (IHP). The TPC and TFC of red ginger and lemongrass combination in five different ratios were determined by standard UV-Vis spectrophotometry methods. The antimicrobial activity was evaluated using the microdilution method against patient-isolated multidrug-resistant (MDR) Staphylococcus aureus and Candida albicans. Lemongrass crude drugs were of good quality, while red ginger did not meet the acid-insoluble ash and volatile matter content requirements. The combination showed the highest TFC in a 75:25% ratio, while that of TPC was 50:50%. All combinations of lemongrass and red ginger extracts inhibited MDR Staphylococcus aureus and Candida albicans with a minimum inhibitory concentration (MIC) of 0.16 mg/ml. Candida albicans were more susceptible to the combination extracts. Red ginger rhizomes and lemongrass leaves 75:25% and 50:50% ratios showing comparable effects to the respective components. Hence, the combination of red ginger and lemongrass in 75:25 and 50:50% ratios potentially developed further for their masuk angin efficacy.

Crude Drugs Standardization, Total Flavonoid and Phenolic Content Profile, and Antimicrobial Activity of Red Ginger and Lemongrass Combination Puspitasari, Adinda; Hamad, Alwani; Hartanti, Dwi
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 2 (2024): December 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i2.2008

Baturraden people use a combination of red ginger rhizomes and lemongrass leaves for the treatment of masuk angin. This study aims to evaluate the quality profile of red ginger and lemongrass crude drug, total flavonoid content (TPC), total phenolic content (TFC), and the antimicrobial activities of their combination water extracts. The quality of both crude drugs was standardized to Indonesian Herbal Pharmacopeia (IHP). The TPC and TFC of red ginger and lemongrass combination in five different ratios were determined by standard UV-Vis spectrophotometry methods. The antimicrobial activity was evaluated using the microdilution method against patient-isolated multidrug-resistant (MDR) Staphylococcus aureus and Candida albicans. Lemongrass crude drugs were of good quality, while red ginger did not meet the acid-insoluble ash and volatile matter content requirements. The combination showed the highest TFC in a 75:25% ratio, while that of TPC was 50:50%. All combinations of lemongrass and red ginger extracts inhibited MDR Staphylococcus aureus and Candida albicans with a minimum inhibitory concentration (MIC) of 0.16 mg/ml. Candida albicans were more susceptible to the combination extracts. Red ginger rhizomes and lemongrass leaves 75:25% and 50:50% ratios showing comparable effects to the respective components. Hence, the combination of red ginger and lemongrass in 75:25 and 50:50% ratios potentially developed further for their masuk angin efficacy.

Pengaruh Kualitas dan Harga Produk Terhadap Minat Beli Salah Satu Produk Kecantikan di Indonesia Puspitasari, Adinda; Putri, Eki Wijayanti; Hutapea, Sharon Nathaniela Badia; Gunawan, Ahmad
Jurnal Ilmiah Mahasiswa Manajemen, Bisnis dan Akuntansi (JIMMBA) Vol. 4 No. 6 (2022): JIMMBA
Publisher : LP3M Universitas Putra Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32639/jimmba.v4i6.206

This study aims to examine, identify, and explain: 1) the effect of product quality on buying intention, 2) the effect of product price on buying intention, and 3) the effect of product quality and price on buying interest. The design of this research is quantitative research which is a research survey using statistical analysis methods. The test results show that product quality (X1) with t count (24,648) > t table (1,984), price (X2) with t count (15,478) > t table (1,984). It can be said that the product quality variable has a significant effect on consumer buying intention, and the price variable has a significant effect on consumer buying interest. The obtained value of Fcount (521.660) > Ftable (3.090) and a significant value (Sig.) less than 0.05 (0.000 < 0.05). This means that the hypothesis which states that there is a significant influence between product quality and the price of consumer buying intention can be accepted.

Crude Drugs Standardization, Total Flavonoid and Phenolic Content Profile, and Antimicrobial Activity of Red Ginger and Lemongrass Combination Puspitasari, Adinda; Hamad, Alwani; Hartanti, Dwi
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 2 (2024): December 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i2.2008

Baturraden people use a combination of red ginger rhizomes and lemongrass leaves for the treatment of masuk angin. This study aims to evaluate the quality profile of red ginger and lemongrass crude drug, total flavonoid content (TPC), total phenolic content (TFC), and the antimicrobial activities of their combination water extracts. The quality of both crude drugs was standardized to Indonesian Herbal Pharmacopeia (IHP). The TPC and TFC of red ginger and lemongrass combination in five different ratios were determined by standard UV-Vis spectrophotometry methods. The antimicrobial activity was evaluated using the microdilution method against patient-isolated multidrug-resistant (MDR) Staphylococcus aureus and Candida albicans. Lemongrass crude drugs were of good quality, while red ginger did not meet the acid-insoluble ash and volatile matter content requirements. The combination showed the highest TFC in a 75:25% ratio, while that of TPC was 50:50%. All combinations of lemongrass and red ginger extracts inhibited MDR Staphylococcus aureus and Candida albicans with a minimum inhibitory concentration (MIC) of 0.16 mg/ml. Candida albicans were more susceptible to the combination extracts. Red ginger rhizomes and lemongrass leaves 75:25% and 50:50% ratios showing comparable effects to the respective components. Hence, the combination of red ginger and lemongrass in 75:25 and 50:50% ratios potentially developed further for their masuk angin efficacy.

REVIEW: EFEKTIFITAS TANAMAN HERBAL PADA AKTIVITAS ANTIBAKTERI STAPHYLOCOCCUS AUREUS Puspitasari, Adinda; Sasmita, Sasmita; Pasaribu, Siti Alo
Jurnal Spektrum Kesehatan Vol 1 No 4 (2025): Vol. 1 No. 4 Desember 2025
Publisher : PT. Media Ilmiah Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37081/rum-kes.v1i4.57

Peningkatan resistensi bakteri terhadap antibiotik mendorong upaya pengembangan alternatif obat antibakteri, salah satunya melalui pemanfaatan bahan alami, tujuan penelitian mengetahui efektivitas tanaman herbal terhadap antibakteri Staphylococcus aureus, metode Systematic Literature Review (SLR), pengumpulan literatur nasional maupun internasional refrensi berupa artikel, dan buku laporan ilmiah menggunakan Google scholar dan ScienceDirec dengan kata kunci “tanaman herbal; Staphylococcus aureus; aktivitas antibakteri”. Analisis data secara deskriptif kualitatif yaitu mengumpulkan Kesimpulan tanaman herbal yang memiliki senyawa aktif yang dominan seperti fenolik, flavonoid, alkaloid, saponin, tanin, triterpenoid, dan steroid berpotensi memberikan efek aktivitas antibakteri yang baik, terdapat beberapa tanaman herbal yang efektif aktivitas antibakteri yaitu daun cengkeh, daun papaya, bunga telang, daun sirih, kulit jeruk nipis, bundung, tanaman cina, daun saga,daun sungkai.

PENDEKATAN KOMUNITAS UNTUK MENURUNKAN ANGKA KEKERASAN BERBASIS GENDER PADA WANITA HAMIL Pasaribu, Siti Alo; Puspitasari, Adinda; Purnamasari, Riska; Agustina, Eka; Has, Ayu Lestari
Jurnal Spektrum Kesehatan Vol 1 No 4 (2025): Vol. 1 No. 4 Desember 2025
Publisher : PT. Media Ilmiah Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37081/rum-kes.v1i4.58

Kekerasan berbasis gender (gender-based violence/GBV), khususnya kekerasan oleh pasangan intim (intimate partner violence/IPV) selama kehamilan, merupakan masalah serius yang berdampak langsung pada komplikasi obstetrik, kesehatan mental ibu, dan hasil neonatal.Tujuan penelitian ini untuk mensintesis bukti terkini mengenai efektivitas berbagai pendekatan komunitas dalam mencegah dan menurunkan angka GBV pada wanita hamil, serta mengidentifikasi komponen intervensi yang paling berkontribusi terhadap perbaikan hasil. Metode yang digunakan adalah tinjauan literatur sistematis terhadap studi empiris terbaru yang mengevaluasi intervensi komunitas, termasuk mobilisasi masyarakat, pendidikan kelompok partisipatif, kunjungan rumah terpadu, dukungan sebaya, dan program pemberdayaan ekonomi. Hasil review menunjukkan bahwa intervensi komunitas yang bersifat multisektoral, berfokus pada perubahan norma sosial, dan melibatkan laki-laki secara aktif memberikan dampak paling menjanjikan dalam penurunan GBV. Namun demikian, bukti yang secara spesifik meneliti populasi wanita hamil masih terbatas dan menunjukkan heterogenitas dalam rancangan penelitian maupun hasil. Temuan ini menekankan perlunya penelitian lebih lanjut dengan desain yang lebih kuat serta integrasi pendekatan komunitas ke dalam praktik kebidanan untuk meningkatkan pencegahan dan penanganan GBV selama kehamilan.

UJI STABILITAS EKSTRAK TERPILIH RAMUAN JAMU SAINTIFIK PENURUN KADAR GULA DARAH Sasmita, Sasmita; Puspitasari, Adinda; Insan, Hafni Nur
Jurnal Spektrum Kesehatan Vol 1 No 4 (2025): Vol. 1 No. 4 Desember 2025
Publisher : PT. Media Ilmiah Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37081/rum-kes.v1i4.64

Penelitian ini bertujuan untuk mengevaluasi stabilitas ekstrak terpilih ramuan jamu saintifik penurun kadar gula darah melalui uji degradasi paksa. Sampel diekstraksi menggunakan beberapa metode, yaitu infusa, dekokta, seduhan, hidrotrop, dan maserasi, kemudian dilakukan pengujian stabilitas terhadap berbagai kondisi stres. Uji degradasi meliputi kondisi asam menggunakan HCl 0,1 N, kondisi basa dengan NaOH 0,1 N, kondisi oksidatif menggunakan H₂O₂ 3%, kondisi termal pada suhu 60 °C, serta uji fotostabilitas. Parameter yang diamati adalah perubahan kadar flavonoid total menggunakan metode spektrofotometri UV–Vis pada hari ke-1, ke-3, dan ke-7. Hasil penelitian menunjukkan bahwa seluruh metode ekstraksi mengalami penurunan kadar flavonoid total seiring waktu penyimpanan pada semua kondisi perlakuan. Degradasi paling signifikan terjadi pada perlakuan suhu tinggi dan paparan cahaya, sedangkan kondisi asam, basa, dan oksidatif juga menyebabkan penurunan kadar yang bermakna. Hal ini menunjukkan bahwa senyawa aktif dalam ekstrak bersifat labil terhadap panas, cahaya, serta kondisi lingkungan ekstrem. Kesimpulannya, ekstrak terpilih ramuan jamu saintifik memiliki potensi sebagai bahan antidiabetik herbal, namun memerlukan pengendalian kondisi penyimpanan yang tepat untuk menjaga stabilitas senyawa aktifnya.

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