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All Journal International Journal of Integrated Health Sciences Journal of Chemical Engineering Research Progress
Vania, Marsha
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Chemical Engineering, Chemistry & Bioengineering Energy Engineering Health Professions Materials Science & Nanotechnology

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Enhancing Propylene Glycol Product Yield by Modifying the Glycerol Hydrogenation Process Syahidah, Aisyah Sabrina Nurul; Vania, Marsha; Aulia, Najmanisa; Hidayah, Nurul; Varado, Isaac
Journal of Chemical Engineering Research Progress 2024: JCERP, Volume 1 Issue 2 Year 2024 (December 2024)
Publisher : UPT Laboratorium Terpadu, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9767/jcerp.20289

Abstract

The production of propylene glycol from glycerol is an emerging and sustainable approach in the chemical industry that can be considered completely renewable. Glycerol, a byproduct of biodiesel production, has gained attention as an alternative feedstock for the synthesis of value-added chemicals such as propylene glycol. This paper evaluates how to perform process modification for optimization of propylene glycol product yield. The process modification was carried out by adding compressor unit before entering a heater, adding heater unit before entering a mixer, and adding 2 separator unit before entering a distillation column. By modifying the addition of compressor unit, heater unit, and 2 separator unit, it has been proven that it can optimizing the propylene glycol product yield by up to 99.75%. Copyright © 2024 by Authors, Published by Universitas Diponegoro and BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Sedative Effects of Intraperitoneal Diazepam in Mice Vania, Marsha; Sari, Shinta Dewi Permata; Siswitono, Bambang; Stujanna, Endin Nokik
International Journal of Integrated Health Sciences Vol 11, No 1 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Objectives: To determine the effectiveness of Diazepam in comparison with Phenobarbital.Methods: Twenty-seven male Swiss Webster mice were used and randomly divided into three groups of negative control (NS), positive control (Phenobarbital), and diazepam group. Two tests were performed on these group: the traction Test and the Fireplace Test. Pupillary diameter was also observed.Results: A significant difference based on the Kruskal - Wallis statistical test was observed between the positive control and the diazepam group (<0.05) in the traction test, which was also true for the fireplaced test (p<0.05). The pupillary diameter in the test animals in the positive control and diazepam group was not statistically significant (p>0.05).Conclusion: Diazepam has a better sedative effect than Phenobarbital. The sedative effect produced by Diazepam is stronger, with faster onset and longer half-life than the Phenobarbital the positive control. However, different test methods and comparisons should be sought to support this conclusion.
Co-Authors Aulia, Najmanisa NURUL HIDAYAH Sari, Shinta Dewi Permata Siswitono, Bambang Stujanna, Endin Nokik Syahidah, Aisyah Sabrina Nurul Varado, Isaac