Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Ensiklopedia of Journal Journal of Health Science and Medical Therapy Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Vonikartika, Arie
Unknown Affiliation
Arts Humanities Chemistry Computer Science & IT Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
EFEK SEDUHAN BUBUK KAYU MANIS TERHADAP GLUKOSA DARAH PENDERITA DIABETES MALLITUS TIPE 2 Vonikartika, Arie; M. Hutapea, Albert
Ensiklopedia of Journal Vol 7, No 1 (2024): Vol. 7 No. 1 Edisi 1 Oktober 2024
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i1.2544

Abstract

Diabetes is a silent killer that can kill, kill. Diabetes mellitus (DM) is caused by impaired pancreatic function, where the pancreas does not produce enough insulin or cannot use insulin effectively. DM is often characterized by chronic hyperglycemia. Diabetes Mellitus (DM) is a non-communicable disease (NCD) which is a public health problem, and has a fairly high number of sufferers in the world. There are many ways to treat and prevent DM, including changing a healthier lifestyle and using herbal treatment which can improve hyperglycemia in DM patients, one of which is cinnamon. Objective: to determine the effect of administering cinnamon powder on blood glucose in diabetes mellitus sufferers. Method: literature review design, journal data sources were obtained through a search using the database: Crom, Goggle scholer, journals published in 2019-2023. The journal data list in this study was created based on title, full title, full text and methodology assessed for study feasibility. Data tabulation and narrative analysis and study findings were conducted. Results and analysis: based on a journal that discusses the effect of cinnamon powder on reducing blood glucose in T2DM sufferers. Conclusion: giving cinnamon powder to diabetes mellitus sufferers can reduce blood sugar levels. This is because polyphenols help insulin to enter blood sugar into cells that accumulate in blood vessels so that the body's metabolic processes are fulfilled. Keywords: Diabetes Mellitus, Cinnamon Powder, Blood glucose, Effect, literature review.
Effects of Cinnamon Bark Extract, Moderate Intensity Exercise, Intermittent Fasting, Metformin on Fasting Blood Glucose Levels, Lipid Profile and Malondialdehyde in DMT2 Rats: Case Study Vonikartika, Arie
Journal of Health Science and Medical Therapy Том 3 № 02 (2025): Journal of Health Science and Medical Therapy
Publisher : PT. Riset Press International

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59653/jhsmt.v3i02.1884

Abstract

Diabetes is a silent killer. Diabetes mellitus (DM) occurs when the pancreas does not produce enough insulin or the body cannot use insulin effectively. DM is often characterised by chronic hyperglycemia. Diabetes Mellitus (DM) is one of the Non-Communicable Diseases (NCDs), which is a public health problem and has a relatively high number of sufferers in the world. Many ways are used to treat and prevent DM, including changing to a healthier lifestyle and using modern medicine or herbal medicine that can improve hyperglycemia in DM patients. This study was conducted to determine the effects of cinnamon extract with a dose of 120 mg / kgBW / day orally, moderate swimming exercise, and intermittent fasting for 19 days on T2DM Rats. The study shows that there was a significant increase (p<0.005) in Fasting Blood Glucose (FBG) between day 1 and day 4 in the untreated group. In the group given metformin, there was a significant change in FBS on day 1 and day 4. In the group given cinnamon extract, there was a change in FBG on days 1 and 4 (increase) and days 10 and 13 (decrease). In the swimming group, there was an increase in FBG on day 1 and day 4 and a significant decrease in FBS on days 10 and 14, while in intermittent fasting, there was an increase in FBS on day 1 and day 4, which was statistically significant. Increases and decreases in lipid and Malondialdehyde (MDA) profiles were also present in each treatment group. The conclusion is that cinnamon bark extract, moderate-intensity swimming exercise, and intermittent fasting impact fasting blood glucose levels, lipid profiles, and MDA in Diabetes induced rats.
FORMULASI DAN UJI EVALUASI SEDIAAN SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) DARI EKSTRAK METANOL AKAR PANDAN LAUT (PANDANUS ODORIFER) Ghiffari, Habibie Deswilyaz; Suhendra, Arif; Vonikartika, Arie; Roza Erda
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 11 No. 2 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i2.964

Abstract

Background: Pandanus odorifer is a coastal plant in Southeast Asia with roots rich in bioactive compounds such as phenolics, flavonoids, saponins, and alkaloids. Limited solubility and bioavailability of lipophilic compounds hinder therapeutic effectiveness. Objective: To develop and evaluate Self-Nanoemulsifying Drug Delivery System (SNEDDS) formulation from sea pandanus root methanol extract to enhance solubility and stability. Methods: Root extraction was performed using soxhlet method with methanol solvent. Six SNEDDS formulas were developed with variations of Tween 80/Tween 20 surfactant combinations and PEG 400/propylene glycol cosurfactants. Evaluation included simplicia characterization, organoleptic tests, creaming tests, pH and viscosity measurements, centrifugation, freeze-thaw stability, solubility, and droplet size analysis. Results: Extract yield reached 7.72% with simplicia characterization meeting pharmacopoeial standards. Formula F3 (Tween 80 21.4%, PEG 400 21.4%, VCO 4.75%, extract 5%) demonstrated optimal stability with pH 6.91±0.04, viscosity 253.33±11.55 cPs, HLB value 14.50, and average droplet size 530 nm. This formula maintained homogeneity throughout all stability tests without phase separation. Conclusion: SNEDDS from Pandanus odorifer root methanol extract formula F3 possesses physicochemical characteristics and stability suitable for nanoemulsion-based drug delivery systems.
Co-Authors Ghiffari, Habibie Deswilyaz M. Hutapea, Albert Roza Erda Suhendra, Arif