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All Journal Journal of Innovation Research and Knowledge Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE)
Rima Hindriani
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Humanities Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Review Metode Ekstraksi : Maserasi, Perkolasi, Infusa, Soxhlet, Refluks, Ultrasonic Assisted Extraction (UAE), dan Microwave Assisted Extraction (MAE) Amaliya Bunga Dwiyanti; Devira Niken Putri Ferdinand; Mifta Dewi; Musa’adah Musa’adah; Noor Mila Wati; Rima Hindriani
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 3 (2025): Desember : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i3.6465

Abstract

Extraction is a crucial process for obtaining active compounds from natural materials, such as medicinal plants, spices, and other biomass. The success of the extraction process is greatly influenced by the method used, as each method has its own mechanism, efficiency, and yield. This study compared seven commonly used extraction methods: maceration, percolation, infusion, soxhletation, reflux, Ultrasound-Assisted Extraction (UAE), and Microwave-Assisted Extraction (MAE). Based on data collected from various scientific journals, it was found that modern methods such as UAE and MAE are capable of producing higher yields than conventional methods. Furthermore, both methods are more efficient in terms of extraction time and solvent usage, making them more environmentally friendly and suitable for industrial-scale applications. However, conventional methods such as maceration and percolation still play an important role, especially in initial research or in laboratories with limited equipment. For example, maceration is easy to perform, does not require high energy, and is suitable for heat-sensitive materials. Other factors that influence extraction results include the type of solvent, temperature, time, and the characteristics of the natural material itself. Therefore, the choice of extraction method must be tailored to the research objectives, the type of compound to be extracted, and the availability of resources and equipment. Combining several methods can also be considered to improve the efficiency and quality of the extraction results. It should be emphasized that extraction yield is influenced not only by the method, but also by the type of material, solvent, temperature, time, and particle size. Therefore, the choice of extraction method must be tailored to the nature of the material, the type of target compound, as well as the objectives and availability of resources. In some cases, a combination of extraction methods can also be used to increase efficiency and obtain optimal results.
RIVIEW TENTANG BERBAGAI FORMULASI TABLET MENGGUNAKAN METODE KEMPA LANGSUNG Rima Hindriani; Raudatul Hasanah; Hayatun Nissa; Fathiyatur Rahmah; Adelia Ikrima; Muhammad Rizky; Nor Latifah
Journal of Innovation Research and Knowledge Vol. 4 No. 7: Desember 2024
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v4i7.9064

Abstract

Penelitian ini bertujuan untuk membandingkan formulasi tablet menggunakan metode kempa langsung, yang merupakan teknik produksi tablet yang efisien, cepat, ekonomis dan mengurangi penggunaan bahan pengikat dan pelarut serta banyak digunakan dalam industri farmasi. Lima jurnal studi yang dianalisis untuk mengidentifikasi pengaruh berbagai bahan pengisi dan tekanan kompresi terhadap sifat fisik tablet. Hasil penelitian menunjukkan bahwa penggunaan bahan pengisi seperti Avicel pH 102 dan pati pregelatinasi beras ketan putih memberikan dampak signifikan pada kekerasan, kerapuhan, dan waktu hancur tablet. Selain itu, tekanan kompresi juga berpengaruh terhadap kualitas tablet yang dihasilkan. Review ini menegaskan bahwa pemilihan bahan dan parameter proses yang tepat sangat penting untuk mencapai tablet berkualitas tinggi. Penelitian lebih lanjut diperlukan untuk mengeksplorasi kombinasi bahan dan parameter yang dapat meningkatkan efisiensi dan kualitas produksi tablet.
Co-Authors Adelia Ikrima Amaliya Bunga Dwiyanti Devira Niken Putri Ferdinand Fathiyatur Rahmah Hayatun Nissa Mifta Dewi Muhammad Rizky Musa’adah Musa’adah Noor Mila Wati Nor Latifah Raudatul Hasanah