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All Journal Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Devira Niken Putri Ferdinand
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Review Jurnal: Evaluasi Kekerasan Sediaan Tablet Kunyah dengan Metode Kempa Langsung Ghina Faiha; Rina Suspa Nita; Nadia Nadia; Devira Niken Putri Ferdinand; Akhmad Rizky Akbar; Nor Latifah
An-Najat Vol. 2 No. 4 (2024): NOVEMBER - An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i4.1956

Abstract

Tablets are one of the most widely used forms of preparation on the market, one type of tablet preparation is chewable tablets. Chewable tablets are drugs that are consumed by chewing first before being swallowed. The manufacture of chewable tablets usually uses the direct felt method which is done by directly shaking a mixture of powder (active substances and excipients). The purpose of this article is to analyze various aspects related to the quality, efficiency, and stability of chewable tablets made using the direct felt method, to identify the hardness test parameters. The method used in this article includes a literature analysis from five journals that discuss the hardness test on chewable tablets on several formulations used. The level of hardness on the tablet was carried out using a hardness tester. Tablets are declared good or meet the requirements when at a weight of 4-8kg the tablets are crushed.
Review Metode Ekstraksi : Maserasi, Perkolasi, Infusa, Soxhlet, Refluks, Ultrasonic Assisted Extraction (UAE), dan Microwave Assisted Extraction (MAE) Amaliya Bunga Dwiyanti; Devira Niken Putri Ferdinand; Mifta Dewi; Musa’adah Musa’adah; Noor Mila Wati; Rima Hindriani
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 3 (2025): Desember : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i3.6465

Abstract

Extraction is a crucial process for obtaining active compounds from natural materials, such as medicinal plants, spices, and other biomass. The success of the extraction process is greatly influenced by the method used, as each method has its own mechanism, efficiency, and yield. This study compared seven commonly used extraction methods: maceration, percolation, infusion, soxhletation, reflux, Ultrasound-Assisted Extraction (UAE), and Microwave-Assisted Extraction (MAE). Based on data collected from various scientific journals, it was found that modern methods such as UAE and MAE are capable of producing higher yields than conventional methods. Furthermore, both methods are more efficient in terms of extraction time and solvent usage, making them more environmentally friendly and suitable for industrial-scale applications. However, conventional methods such as maceration and percolation still play an important role, especially in initial research or in laboratories with limited equipment. For example, maceration is easy to perform, does not require high energy, and is suitable for heat-sensitive materials. Other factors that influence extraction results include the type of solvent, temperature, time, and the characteristics of the natural material itself. Therefore, the choice of extraction method must be tailored to the research objectives, the type of compound to be extracted, and the availability of resources and equipment. Combining several methods can also be considered to improve the efficiency and quality of the extraction results. It should be emphasized that extraction yield is influenced not only by the method, but also by the type of material, solvent, temperature, time, and particle size. Therefore, the choice of extraction method must be tailored to the nature of the material, the type of target compound, as well as the objectives and availability of resources. In some cases, a combination of extraction methods can also be used to increase efficiency and obtain optimal results.
Co-Authors Akhmad Rizky Akbar Amaliya Bunga Dwiyanti Ghina Faiha Mifta Dewi Musa’adah Musa’adah Nadia Nadia Noor Mila Wati Nor Latifah Rima Hindriani Rina Suspa Nita