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All Journal Jurnal Biologi Tropis Promotor: Jurnal Mahasiswa Kesehatan Masyarakat
Nazilinly, Fitri
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health Other

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Congenital Talipes Equinovarus (CTEV): A Literature Review Saputra, Kurniawan Aditya; Kamilah, Nilam Nurmilatun; Lovely, Anjela Fatma; Faqih, Fauzan; Nazilinly, Fitri; Murniati, Rinesita; Firdaus, Royan Alfian; Mutia, Baiq Marceliya Anjani; Putri, Radiah Meilani; Putra, Rifky Sandya Rakadi; Rahman, Hadian
PROMOTOR Vol. 8 No. 3 (2025): JUNI
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v8i3.1232

Abstract

Congenital talipes equinovarus (CTEV) is a congenital foot deformity affecting one or both extremities with a global prevalence estimated at 0.6-1.5 per 1000 live births. The exact etiology of CTEV remains unclear, although genetic and environmental factors are thought to play significant roles. The deformities in CTEV typically include malposition of the tarsal bones, calf muscle atrophy, and shortening of the affected limb. This article aims to provide additional information on CTEV to facilitate early screening and improve patient prognosis. This study employed a literature review method covering the definition, epidemiology, etiology, pathological anatomy, pathogenesis, clinical manifestations, diagnosis, scoring systems, and management of CTEV. Data were obtained through electronic searches in PubMed, ProQuest, ScienceDirect, and Google Scholar databases.
Antibacterial Activity of Ethyl Asetate Fraction of Centella asiatica Against Clinical Isolates of Pseudomonas aeruginosa Nazilinly, Fitri; Permatasari , Lina; Hasbi, Nurmi
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7450

Abstract

Pseudomonas aeruginosa is one of the major worldwide medical conditions causing nosocomial contaminations with high mortality and grimness. P. aeruginosa infection treatment, on the other hand, has become more difficult due to antibiotic resistance. Therefore, new antibacterial agents are needed that can be an option in controlling and managing cases of bacterial infections. Plants that could potentially become a new antimicrobial agent is pegagan herb (Centella asiatica). This study aims to determine the antibacterial activity of ethyl acetate fraction of pegagan herb against clinical isolates of P. aeruginosa and its phytochemical profile. Pegagan herb powder was extracted with 96% ethanol, then fractionated using liquid-liquid extraction method with n-hexane, chloroform and ethyl acetate solvents. Ethyl acetate fraction of pegagan herb with 3 treatment groups of 5,000 ppm, 7,500 ppm, and 10,000 ppm were tested for antibacterial activity using disc diffusion method. The positive and negative control groups used Colistin and DMSO 10%. The results showed that all concentrations produced different inhibition zones against the growth of P. aeruginosa. Based on the mean diameter of inhibition, the concentration series of 7,500 ppm showed the most effective results with a mean of 2.69 mm compared to the other concentrations. Ethyl acetate fraction of pegagan herb contains flavonoid, phenolic and tannin compounds. Ethyl acetate fraction of pegagan herb can inhibit the growth of clinical isolates of P. aeruginosa in the weak category with inhibition zone diameter <5 mm.
Choledochal Cyst: Case Variations and Management Girsang, Andrew Deardo Purba; Fattahillah T, Rizqy Agung; Nazilinly, Fitri; Kamilah, Nilam Nurmilatun; Pramudya, I Nengah Andra Putra; Mario, Andina Nabilah; Faqih, Fauzan; Zuhan, Arif
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7985

Abstract

Choledochal Cyst (CC) is a congenital anomaly characterized by the dilation of intrahepatic and/or extrahepatic bile ducts. This condition can occur at any age but is more common in infants and children, accounting for 80% of cases. This study aims to evaluate the clinical characteristics, diagnostic approaches, and optimal management options for choledochal cysts, accompanied by case variations. The method used in this study is a literature review, gathering relevant literature from various references focused on the topic of choledochal cysts. Literature searches were conducted using library search websites, including PubMed, ScienceDirect, Cochrane Library, Google Scholar, and ProQuest, with the search keyword "Choledochal Cyst." The review indicates that choledochal cysts are more common in females and people of Asian descent, especially in Japan, with the most common symptoms presenting as the classic triad of abdominal pain, jaundice, and a palpable mass in the right upper quadrant of the abdomen. This condition is more frequently diagnosed in children than in adults. Further research is needed to explore definite preventive efforts regarding this disease, as it is rare and its etiology remains uncertain.
Co-Authors Faqih, Fauzan Fattahillah T, Rizqy Agung Firdaus, Royan Alfian Girsang, Andrew Deardo Purba Hasbi, Nurmi - Kamilah, Nilam Nurmilatun Lovely, Anjela Fatma Mario, Andina Nabilah Murniati, Rinesita Mutia, Baiq Marceliya Anjani Permatasari , Lina Pramudya, I Nengah Andra Putra Putra, Rifky Sandya Rakadi Putri, Radiah Meilani Rahman, Hadian Saputra, Kurniawan Aditya Zuhan, Arif