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All Journal ZIRAA'AH MAJALAH ILMIAH PERTANIAN
Pangestu, Muhammad Syahid Panji
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Agriculture, Biological Sciences & Forestry

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THE EFFECT SNPs R25C AND R25H LEPTIN GENE TO CHOLESTEROL AND TRIGLYCERIDE ON BLOOD OF ONGOLE CROSSBREED CATTLE Hilmia, Nena; Dudi, Dudi; Edianingsih, Primiani; Mushawir, Andi; Susilawati, Iin; Pangestu, Muhammad Syahid Panji; Widyastuti, Rini
ZIRAA'AH MAJALAH ILMIAH PERTANIAN Vol 50, No 1 (2025)
Publisher : Pusat Publikasi Jurnal Universitas Islam Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/zmip.v50i1.18069

Abstract

Single Nucleotide Polymorphisms (SNPs) on the Leptin gene may alter the quality and quantity of Leptin hormone, which plays an active role in energy metabolism and it can contribute to fat deposition in mammals. This study proposed to determine the effect of SNPs R25C and R25H on Cholesterol, and Triglycerides levels in the blood of Ongole Crossbreed cattle. The research was carried out experimentally with a Completely Randomized Design using the sixteen heads of Ongole Crossbreed. There were three different genotypes based on SNPs R25C and R25H: CC, TT, and  AA. The cattle were reared intensively for two months. The feed consists of corn kernels and concentrates, and It is calculated based on the Dry Matter (DM) intake, which is 3% of body weight. The result showed SNPs R25C and R25H on the Leptin gene did not have a significant effect on blood Cholesterol, and Triglyceride levels of Ongole Crossbreed cattle. Those SNPs in the Leptin gene cannot be used as selection markers in Ongole Crossbreed cattle. Further research is needed to include SNPs in other genes contributing to Cholesterol and Triglycerides on blood cattle
THE EFFECT SNPs R25C AND R25H LEPTIN GENE TO CHOLESTEROL AND TRIGLYCERIDE ON BLOOD OF ONGOLE CROSSBREED CATTLE Hilmia, Nena; Dudi, Dudi; Edianingsih, Primiani; Mushawir, Andi; Susilawati, Iin; Pangestu, Muhammad Syahid Panji; Widyastuti, Rini
ZIRAA'AH MAJALAH ILMIAH PERTANIAN Vol 50, No 1 (2025)
Publisher : Pusat Publikasi Jurnal Universitas Islam Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/zmip.v50i1.18069

Abstract

Single Nucleotide Polymorphisms (SNPs) on the Leptin gene may alter the quality and quantity of Leptin hormone, which plays an active role in energy metabolism and it can contribute to fat deposition in mammals. This study proposed to determine the effect of SNPs R25C and R25H on Cholesterol, and Triglycerides levels in the blood of Ongole Crossbreed cattle. The research was carried out experimentally with a Completely Randomized Design using the sixteen heads of Ongole Crossbreed. There were three different genotypes based on SNPs R25C and R25H: CC, TT, and  AA. The cattle were reared intensively for two months. The feed consists of corn kernels and concentrates, and It is calculated based on the Dry Matter (DM) intake, which is 3% of body weight. The result showed SNPs R25C and R25H on the Leptin gene did not have a significant effect on blood Cholesterol, and Triglyceride levels of Ongole Crossbreed cattle. Those SNPs in the Leptin gene cannot be used as selection markers in Ongole Crossbreed cattle. Further research is needed to include SNPs in other genes contributing to Cholesterol and Triglycerides on blood cattle
Co-Authors dudi, dudi Edianingsih, Primiani Iin Susilawati Mushawir, Andi Nena Hilmia Rini Widyastuti