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All Journal Berkala Kedokteran Journal of Pharmaceutical Care and Sciences
Norlita, Devi
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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S Studi Farmakovigilans Vaksinasi Booster Covid-19 Pada Masyarakat Di Desa Pujon Kalimantan Tengah: Studi Farmakovigilans Vaksinasi Booster Covid-19 Pada Masyarakat Di Desa Pujon Kalimantan Tengah Norlita, Devi; Yuwindry, Iwan; Aryzki, Saftia; Melviani, Melviani
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 1 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i1.648

Abstract

Background: Covid-19 booster vaccination is expected to achieve herd immunity (group immunity) forming antibodies or strong immunity so that people can survive the Covid-19 virus and hopefully the Covid-19 pandemic will turn into a Covid-19 epidemic. Adverse Drug Reactions (ROM) are unwanted side effects of a drug that arise when administering the drug at a dose used for prophylaxis, diagnosis, and therapy that is actual or potential.Objective: To determine the Pharmacovigilance Study of Covid-19 booster vaccination in the Pujon Village community, Central Kalimantan.Method: This study is Observational in nature, Quantitative. with a descriptive research method, the approach used in this study is cross-sectional. The study was conducted in July in the Pujon Village environment, Central Kalimantan.Results: From the side effects of the Covid-19 booster vaccination, namely the results of the Naranjo Algorithm measurement, it is known that out of 98 respondents, the Pujon village community received the most results in the Naranjo Probable category, which is a side effect of the Covid-19 vaccination, with 20 respondents (20.41%). It is known that there were 55 respondents who experienced possible side effects. Among them, 25 had fever and 30 had pain after receiving the Covid-19 vaccination.Conclusion: From the side effects of the Covid-19 booster vaccination, namely the results of the Naranjo Algorithm measurement, it is known that out of 98 respondents, the Pujon village community received the most results in the Naranjo Possible category, which is a possible side effect of the Covid-19 vaccination, with 55 respondents (56.12%). It is known that there were 55 respondents who experienced possible definite side effects. Among them, 25 had fever and 30 had pain after receiving the Covid-19 vaccination
Activity of Manau Rattan (Calamus manan) Seeds Extract on Reducing Blood Glucose Levels of Male Swiss Webster Mice Komaliya, Risyda; Aryzki, Saftia; Montella, Clara; Norlita, Devi; Mubarak, Jaki
Berkala Kedokteran Vol 21, No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v21i2.24967

Abstract

Diabetes mellitus is a degenerative disease characterized by high blood sugar levels caused by disturbances in insulin secretion in the body. One alternative in dealing with diabetes mellitus is traditional medicine using natural ingredients. One of the plants that has the potential to have anti-diabetic activity is the Manau Rattan Seed (Calamus manan). This study aims to determine the decrease in blood glucose levels of Swiss Webster male white mice using the experimental method with the glucose tolerance method. The test animals were divided into seven groups, namely group I being a negative control given glucose 2 g/Kg BW, groups II and III being positive controls each given metformin at a dose of 1.3 mg/Kg BW, and glibenclamide at a dose of 0 .65 mg/Kg BW, and groups IV, V, VI and VII became the test material from manau rattan seed extract with respective levels of 100 mg/Kg BW, 200 mg/Kg BW, 300 mg/Kg BW, and 400 mg/Kg BW. Based on the results of the data, the percentage of decreased blood glucose levels (%) showed that the best reduction in glucose levels was in group III (glibenclamide) with an average yield of 41.95%. Parametric analysis used One Way ANOVA with a significance value of >0.05, namely 0.431, so there was no significant difference.
Co-Authors Aryzki, Saftia Komaliya, Risyda Melviani, Melviani Montella, Clara Mubarak, Jaki Yuwindry, Iwan