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EVALUASI RASIONALITAS PENGOBATAN HIPERTENSI DI PUSKESMAS PELAMBUAN BANJAR MASIN TAHUN 2017 Aryzki, Saftia; Aisyah, Noor; Hutami, Hesti; Wahyusari, Besty
Jurnal Ilmiah Manuntung Vol 4 No 2 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (78.6 KB)

Abstract

Irrational use of drugs is still found in Puskesmas which is the First Level Health Facilities. The use of irrational drugs based on appropriate drugs and precise indications. In the use of various types of drugs there may be an irrationality of treatment, one of which is hypertension.This study aims to determine the antihypertensive drugs used in Pelambuan Puskesmas Banjarmasin and to determine the percentage of rationality of hypertension treatment at Pelambuan Puskesmas Banjarmasin. evaluating the rationale for the use of antihypertensive drugs that include the accuracy of indication, drug, dose, patient, mode of administration, and duration of administration in hypertensive patients at Puskesmas Pelambuan Banjarmasin during 2017. This type of research was descriptive non-experimental research with retrospective data retrieval based on medical records of hypertensive patients in 2017. The population in this study amounted to 333 medical records and the number of samples that met the inclusion and exclusion criteria as much as 37 medical records. The tools / instruments in this study were observation sheets and interview sheets. The results of the research on antihypertensive drugs used in Pelambuan Banjarmasin Health Center were amlodipine, nifedipine, captopril, lisinopril. The results of the evaluation of the rationality of the use of antihypertensive drugs were seen based on the exact indication criteria as many as 18 patients (48,65%), right medication as many as 18 patients (48,65%), right dose of 17 patients (45,95%), right patients as many as 33 patients (89,19%), the exact method of administration was 31 patients (83,79%), and the exact duration of administration was 22 patients (59,46%).
Hubungan Tingkat Kepatuhan Penggunaan Obat Antihipertensi Dengan Kontrol Tekanan Darah Pada Pasien Hipertensi Di Puskesmas Terminal Banjarmasin Humaira, Muhammad Nurridho Alfian; Mustaqimah, Mustaqimah; Aryzki, Saftia
Jurnal Farmasi SYIFA Vol 1 No 2 (2023): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v1i2.181

Abstract

Hipertensi merupakan salah satu penyakit yang meningkat seiring perkembangan zaman dan paling banyak diderita oleh masyarakat Indonesia, dimana penderita mengalami peningkatan tekanan darah ≥140/90 mmHg. Keberhasilan dan kesembuhan pasien dalam terapi hipertensi dipengaruhi oleh beberapa faktor, salah satunya yaitu kepatuhan pasien dalam minum obat. Tujuan penelitian mengetahui hubungan tingkat kepatuhan penggunaan obat antihipertensi dengan kontrol tekanan darah pada pasien hipertensi di Puskesmas Terminal Banjarmasin. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan Cross Sectional, pengumpulan data dilakukan secara prospektif menggunakan kuesioner kepatuhan Hill-Bone yang telah diuji validitas dan reliabilitas. Penelitian ini mendapatkan hasil uji statistik dengan nilai p = 0,000 < α 0,05 menggunakan uji spearman rho correlation yang artinya Ho ditolak dan Ha diterima. Simpulan dari penelitian ada hubungan mengenai tingkat kepatuhan penggunaan obat antihipertensi dengan kontrol tekanan darah pada pasien hipertensi di Puskesmas Terminal Banjarmasin.
Compliance of Pharmacy Service Standards at The Phcussia of Banjarmasin City Nufus, Hayatun; Aryzki, Saftia; Malahayati, Siti; Kurniawati, Darini
Berkala Kedokteran Vol 20, No 2 (2024)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v20i2.20596

Abstract

Pharmaceutical work carried out in the acquisition, production, distribution and maintenance of drugs must be carried out by health workers who have the appropriate knowledge and authority for that. Based on the description above, researchers are very interested in knowing whether or not there is a conformity of pharmaceutical service activities in all Banjarmasin city health centers based on Permenkes RI No. 26 of 2020 related to Pharmaceutical Service Standards. The purpose of this study was to determine the suitability of Pharmaceutical Services at public health center in Banjarmasin City against Permenkes No. 26 of 2020 concerning Pharmaceutical Service Standards at public health center. The research design method used is observation, namely making direct observations accompanied to obtain information on the Management of Pharmaceutical Supplies and Consumable Medical Materials, as well as Clinical Pharmacy Services. There are 26 health centers in Banjarmasin City. All health centers have met the suitability of pharmaceutical preparation management and Medical Consumables (BMHP) in accordance with the Minister of Health Regulation No. 26 of 2020. However, 10 public health center in Banjarmasin City have not met the requirements of clinical pharmacy services, such as Counseling, Monitoring Drug Side Effects, Monitoring Drug Therapy, and Evaluating Drug Use. This is influenced by limited human resources at these health centers. 26 health centers in Banjarmasin City are appropriate in managing pharmaceutical preparations and Consumable Medical Materials (BMHP) and 16 health centers are appropriate in implementing clinical pharmacy services.
Cost Minimization Analysis of Oral Antidiabetic Drugs in Type II Diabetes Mellitus Patiens at Sultan Suriansyah Hospital January-December 2022 Period Ain, Farah Noor; Aryzki, Saftia; Abdi, Muhammad Mahendra
Berkala Kedokteran Vol 20, No 1 (2024)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v20i1.18764

Abstract

Diabetes According to WHO (2016) is a serious chronic disease that occurs when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. The high cost of treating DM patients is reaching USD 1,500 to 9,000 in developing countries. The difference in costs for oral antidiabetics and the high cost analysis method. This study aims to determine the minimum cost between metformin 500 mg and acarbose 100 mg drugs in Sultan Suriansyah Banjarmasin in adult patients. This research was conducted using a cross-sectional design based on medical records and detail of patient costs in January-December 2022. The number of sample in this study were 39 patients. The statistic analysis used in study is the Mann-Whitney test and the Independent T-Test. The result of the analysis of cost minimization based on the average total cost of therapy are Rp 419,560 for metformin 500ng and Rp 680,922 for acarbose 100 mg with a probability value > 0.05 for the cost of co morbidities which means that there is no significant difference between the two drugs. Probability value < 0.05 for antidiabetic oral drug costs, lab costs and total therapy costs which means the there is a significant difference between the two drugs. Conclusion in this study is aral antidiabetic therapy for minimal diabetes mellitus is metformin compared to acarbose.
Formulation and Evaluation of Physical Quality of Peel-Oof Masks of Essential Oils of Galam Kalimantan Plants Ayuchecaria, Noverda; Karelius, Karelius; Rosmainar, Lilis; Aryzki, Saftia
Berkala Kedokteran Vol 20, No 1 (2024)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v20i1.18766

Abstract

The Kalimantan galam plant (Melaleuca cajuputi subsp cajuputi) has been used for generations but its use is very limited, only as wooden piles which form the basis of buildings in swamps (cerucuk), pillars for building construction, stakes (supports for newly planted seedlings) and siring. Street. The use of galam essential oil as an active ingredient in peel-off mask preparations can be efficacious in reducing inflammation and infection of acne or other skin problems. Facial masks in the form of peel-off itself have many advantages, namely their practical use and are easy to remove or lift like elastic membranes compared to conventional masks which leave residue. This study aims to design a peel-off mask formulation by utilizing the active ingredient in the essential oil of the galam plant. The preparations were then tested for physical quality requirements including organoleptic tests, homogeneity tests, pH tests, drying time tests, spreadability and adhesion tests. The results of the tests that have been carried out include the extraction of essential oils as the active substance. The yield of essential oil obtained was 0.12%. Organoleptic quality tests showed changes in color, smell and shape in the three formulations. The homogeneity test for formulas I and II remained homogeneous, while for formula III the consistency changed to 2 layers. The pH test showed that all formulations met the pH requirements for topical preparations, namely 4-8. The drying time test for formula I was more difficult to remove, formula II was not too stiff while formula III was stiffer. Spreadability test on formulas I, II and III 5-7 cm. The gel viscosity test decreased and the adhesion test on formulation I was easily released, formulas II and III were not easily released while the irritation test of 30 people did not experience redness in 3 formulas.
Aktivitas Baccaurea motleyana Mull.Arg. terhadap Salmonella thypi Febrianti, Dwi Rizki; Aryzki, Saftia; Khadijah, Maulida; Kumalasari, Eka; Niah, Rakhmadhan
Jurnal Pharmascience Vol 11, No 2 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.16498

Abstract

Penyakit tifus adalah gangguan pada sistem pencernaan yang menyerang bagian usus halus dan terkadang dapat mempengaruhi aliran darah, kantong empedu, limfa, dan hati. Penyebab utama tifus adalah aktivitas bakteri Salmonella thypi, bakteri ini mampu mengontaminasi makanan ataupun minuman yang tidak terjaga sanitasinya. Baccaurea motleyana Mull.Arg memiliki kandungan senyawa antibakteri, diantaranya golongan flavonoid, saponin, dan tanin. Penelitian ini bertujuan untuk membuktikan aktivitas ekstrak daun rambai dalam menghambat S. thypi. Penelitian ini menggunakan metode ekstraksi maserasi dan uji antibakteri menggunakan metode difusi sumuran menggunakan nutrien agar (NA). Ekstraksi dengan maserasi dilakukan menggunakan pelarut etanol 70%. Kelompok perlakuan pada penelitian ini menggunakan seri  konsentrasi ekstrak 10%, 20%, 30%, dan kontrol negatif (water for injection) dengan tiga kali pengulangan. Ukuran diameter zona bening yang terbentuk diukur menggunakan jangka sorong digital. Hasil penelitian menunjukkan bahwa ekstrak daun rambai memiliki efek penghambatan terhadap pertumbuhan bakteri S. thypi. Rerata zona hambat dari ekstrak daun rambai dengan konsentrasi 10%, 20%, dan 30% masing-masing adalah 14,1 mm; 18,8 mm; dan 23,13 mm, sehingga dapat disimpulkan bahwa ekstrak daun B. motleyana memiliki aktivitas terhadap bakteri S. thypi. Kata Kunci: Antibakteri,  Zona Bening, Daun Rambai,  Difusi Padat, Salmonella thypi Typhoid disease is a disorder of the digestive system that attacks parts of the small intestine and can sometimes affect blood flow, gallbladder, lymph, and liver. The main cause of typhus is the activity of Salmonella thypi bacteria, this bacterium is able to contaminate food or drinks that are not maintained sanitation. Baccaurea motleyana Mull.Arg contains antibacterial compounds, including flavonoids, saponins, and tannins. This study aims to prove the activity of rambai leaf extract in inhibiting S. thypi. This study uses the maceration extraction method and antibacterial test using the well diffusion method using agar nutrients (NA). Extraction by maceration is carried out using a 70% ethanol solvent. The treatment group in this study used a series of 10%, 20%, 30% extract concentrations, and negative control (water for injection) with three repetitions. The size of the diameter of the formed clear zone is measured using a digital caliper. The results showed that rambai leaf extract had an inhibitory effect on the growth of S. thypi bacteria. The average inhibition zone of rambai leaf extract with concentrations of 10%, 20%, and 30% was 14.1 mm, respectively; 18.8 mm; and 23.13 mm, so it can be concluded that B. motleyana leaf extract has activity against S. thypi bacteria.
Education on the Use of Herbal Plants in the Community to Increase Knowledge in the Use and Manufacture of Herbal Plants Aryzki, Saftia; Okvianingsih, Arum Dwi; Humaira, Muhammad Nurridho Alfian; Astuti, Puspita; Norliani, Rahma; Rahmawati, Siti
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 7, No 1 (2025)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v7i1.13143

Abstract

Education about the use of herbal plants is a step taken to increase public knowledge and empower the potential of medicinal plants. Education aims to increase knowledge in the use and preparation of herbal plants. Some of which people often use are ginger, lemongrass, cinnamon and turmeric. Respondents in the service were from the community in the RT. 16 North Alalak Subdistrict. The ABCD method focuses on the potential assets to be observed, namely herbal plants which are easily obtained by the people of Alalak Utara Subdistrict RT 16 by conducting surveys and distributing leaflets. The data collection technique uses a questionnaire. Based on the results obtained, before the educational activities were carried out and after the educational activities were carried out, the value was obtained from 35% to 100%. Thus, it can be concluded that in this educational activity, there was an increase in knowledge of the use of herbal plants by 65%.
U Uji Aktivitas Antifungi Ekstrak Kulit Batang Tanaman Kenanga (Cananga odorata) Terhadap Jamur Malassezia furfur Intan, Intan; Nastiti, Kunti; Aryzki, Saftia; Darsono, Putri Vidiasari
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 1 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i1.647

Abstract

Background: One of the plants that is efficacious in the world of medicine is the ylang-ylang plant (Cananga odorata), namely the bark of the ylang-ylang plant which is used by the Kapuas people of Central Kalimantan to treat diseases such as tinea versicolor.Objective: To determine the identification of the antifungal activity test of the bark extract of the ylang-ylang plant (Cananga odorata) against the Malassezia furfur fungus and to determine the minimum inhibitory concentration (MIC) and minimum kill concentration (KBM) of the bark extract of the ylang-ylang plant (Cananga odorata) against the fungus Malassezia furfurMethods: Research method Using experimental methods using the Malassezia furfur fungus. Ylang ylang bark extract (Cananga odorata) was screened for phytochemicals such as alkaloids, flavonoids, terpenoids/steroids, tannins and saponins. This study used 3 treatment groups consisting of positive control (ketoconazole 200 mg), negative control (DMSO) and ylang ylang (Cananga odorata) bark extract at concentrations of 25%, 50%, 75% and 100% with disc diffusion and dilution treatments.Results: The bark extract of the ylang-ylang plant (Cananga odorata) contains several secondary metabolites such as alkaloids, flavonoids, terpenoids, tannin saponins and has inhibitory activity using the disc diffusion method with an average diameter of 25.85 mm. Antifungal testing was carried out using the dilution method with a value of MIC is 25% and there is no KBM for the Malassezia furfur fungus.Conclusion: Bark extract of the ylang-ylang plant (Cananga odorata) has antifungal activity against the fungus Malassezia furfur
S Studi Farmakovigilans Vaksinasi Booster Covid-19 Pada Masyarakat Di Desa Pujon Kalimantan Tengah: Studi Farmakovigilans Vaksinasi Booster Covid-19 Pada Masyarakat Di Desa Pujon Kalimantan Tengah Norlita, Devi; Yuwindry, Iwan; Aryzki, Saftia; Melviani, Melviani
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 1 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i1.648

Abstract

Background: Covid-19 booster vaccination is expected to achieve herd immunity (group immunity) forming antibodies or strong immunity so that people can survive the Covid-19 virus and hopefully the Covid-19 pandemic will turn into a Covid-19 epidemic. Adverse Drug Reactions (ROM) are unwanted side effects of a drug that arise when administering the drug at a dose used for prophylaxis, diagnosis, and therapy that is actual or potential.Objective: To determine the Pharmacovigilance Study of Covid-19 booster vaccination in the Pujon Village community, Central Kalimantan.Method: This study is Observational in nature, Quantitative. with a descriptive research method, the approach used in this study is cross-sectional. The study was conducted in July in the Pujon Village environment, Central Kalimantan.Results: From the side effects of the Covid-19 booster vaccination, namely the results of the Naranjo Algorithm measurement, it is known that out of 98 respondents, the Pujon village community received the most results in the Naranjo Probable category, which is a side effect of the Covid-19 vaccination, with 20 respondents (20.41%). It is known that there were 55 respondents who experienced possible side effects. Among them, 25 had fever and 30 had pain after receiving the Covid-19 vaccination.Conclusion: From the side effects of the Covid-19 booster vaccination, namely the results of the Naranjo Algorithm measurement, it is known that out of 98 respondents, the Pujon village community received the most results in the Naranjo Possible category, which is a possible side effect of the Covid-19 vaccination, with 55 respondents (56.12%). It is known that there were 55 respondents who experienced possible definite side effects. Among them, 25 had fever and 30 had pain after receiving the Covid-19 vaccination
P Penetapan Kadar Rhodamin B Pada Kerupuk Opak Bagula Di Kota Banjarmasin Mawarid, Muhammad Taufiq Fawwaz; Aryzki, Saftia; Hidayah, Nur; Rahmadani, Rahmadani
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 1 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i1.656

Abstract

Background: Rhodamine B is a dye that is commonly used in the textile and paper industry, as a fabric dye, cosmetics, oral cleansing products and soap. This dangerous chemical is often misused in food production. This research aims to determine the chemical content in opak crackers which contain synthetic dyes such as rhodamine B circulating in the city of Banjarmasin using the HPLC method.Objective: This study aims to determine the presence and analyze the levels of rhodamine B in opak crackers circulating in the city of Banjarmasin.Methods: This research uses analytical observational research methods. Meanwhile, the design used in this research is cross sectionalResults: The results of qualitative analysis of injection of a standard solution of rhodamine B at a wavelength of 553 nm showed a retention time of 2.123 minutes. The results showed that samples (A), samples (B), samples (C) did not contain rhodamine B, characterized by different retention times. Meanwhile, the results of quantitative analysis using an HPLC instrument showed that no levels of rhodamine B were detected in all samples.Conclusion: Opak crackers circulating in the city of Banjarmasin, especially those sold at the pasar Ahad, Siring, and Taman Kamboja, can be declared safe or suitable for consumption