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All Journal Journal of Islamic Pharmacy BIOCITY: Journal of Pharmacy Bioscience and Clinical Community Jurnal Pengabdian Pada Masyarakat IPTEKS
Amrulloh, Lalu Sanik Wahyu Fadil
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Molecular Docking: Analysis of Mahogany Plant Compounds (Swietenia macrophylla King) against the ACE2 Enzyme of SARS-CoV-2 Amrulloh, Lalu Sanik Wahyu Fadil; Khairani, Ayudia Cipta
Journal of Islamic Pharmacy Vol 10, No 1 (2025): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v10i1.32426

Abstract

Various treatment approaches have been attempted to tackle severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)  infection. One approach to develop new drugs is through the utilization of medicinal plants. Mahogany (Swietenia macrophylla King) is one of the plants that is thought to have potential as an inhibitor of SARS-CoV-2. This study aims to determine the anti-SARS-CoV-2 potential of compounds in mahogany plants that have good interactions and interaction patterns with angiotensin-converting enzime 2 (ACE2) receptors. A total of ten mahogany plant compounds were tested for drug-likeness based on Lipinski screening which will then be docked to the ACE2 molecular target, using the molecular docking method. The parameters observed were binding energy values and amino acid residues. The results of molecular docking showed that the compounds predicted to have the highest binding affinity and have similar interaction patterns with natural ligands to the ACE2 molecular target were secomahoganin and stigmasterol. The secomahoganin and stigmasterol compounds are predicted to have good interactions with the ACE2 receptor.
Uji Kualitatif Kandungan Senyawa Sianida pada Tanaman dengan Metode Pikrat Khairani, Ayudia Cipta; Ariasti, Mia; Muhsin, Lalu Busyairi; Amrulloh, Lalu Sanik Wahyu Fadil; Martayuni, Ruprika Dwi
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 1 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i1.5047

Abstract

Indonesian people have traditionally utilized various local plants as alternative food sources. These plants are widely available and have considerable nutritional value; however, some of them are known to contain toxic compounds such as cyanide (HCN), which can be harmful to human health if not properly processed. Therefore, this study aimed to examine the presence of cyanide compounds in several of these commonly consumed plants. The research was conducted using a qualitative test based on the picrate method. The samples tested included cassava, cassava leaves, bamboo shoots, gadung tubers, and taro tubers. The findings indicated that all tested samples showed positive results for the presence of cyanide, as evidenced by the observed color change from yellow to reddish-brown. In conclusion, all five types of plant samples tested contained cyanide, emphasizing the importance of proper processing techniques to reduce toxicity levels before consumption by the public.
Bakti Sosial Pemeriksaan Gratis Relawan Medis Beriuk Bareng Peduli di Desa Poton Bako Kecamatan Jerowaru, Kabupaten Lombok Timur Wisnu, M Ari; Amrulloh, Lalu Sanik Wahyu Fadil; Pratiwi, Siti Amalia Wahyu; Supraba, Widayanti; Putra, Gilang Pratama; Wahyuni, Ika; Mutmainnah, Zurhainun; Hendriawan, Hendriawan
Jurnal Pengabdian Pada Masyarakat IPTEKS Vol. 3 No. 2 (2026): Jurnal Pengabdian Pada Masyarakat IPTEKS, Maret 2026
Publisher : CV. Global Cendekia Inti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71094/jppmi.v3i2.200

Abstract

This community service activity was conducted in Poton Bako Village, Jerowaru District, where limited access to health services and low public awareness of routine health check-ups were identified. The activity aimed to improve access to healthcare services and promote early disease detection. A descriptive observational approach was used through a free health screening program involving 50 participants aged 3 to 45 years. The implementation included registration, vital signs examination, basic laboratory tests, medical examination by a general practitioner, as well as medication dispensing and education on proper drug use. The results showed that participants obtained initial information about their health conditions and demonstrated increased awareness of the importance of regular health check-ups. The activity also supported preventive efforts through health education and appropriate medication use. It was concluded that free health screening was effective in improving access to healthcare services and increasing community awareness of early disease detection.
Co-Authors Ariasti, Mia Ayudia Cipta Khairani HENDRIAWAN, HENDRIAWAN Ika WAHYUNI Martayuni, Ruprika Dwi Muhsin, Lalu Busyairi Mutmainnah, Zurhainun Pratiwi, Siti Amalia Wahyu Putra, Gilang Pratama Supraba, Widayanti Wisnu, M Ari Wisnu, M. Ari