Article Per Year (5 Year)
p-Index From 2021 - 2026
0.817
P-Index
This Author published in this journals
All Journal Jurnal Pengabdian Magister Pendidikan IPA Indonesian Journal of Pharmacology and Therapy
Septiayu Dwi Hartienah
Unknown Affiliation
Education Immunology & microbiology Medicine & Pharmacology

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Pharmacogenomic of asthma in children Nova Satriyani; Hartati Mahmuda; Septiayu D. Hartienah
Indonesian Journal of Pharmacology and Therapy Vol 3 No 2 (2022)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.2658

Abstract

Asthma is an inflammatory airway disease characterized by bronchial hyper-responsiveness, reversible airflow limitation, and respiratory symptoms. Asthma affects 300 million people in developed countries. More than 10% of asthma complaints in children occur at school age. Asthma therapy in children using pharmacological agents is still the main choice until now. However, the response of pediatric patients to asthma treatment varies. In addition to age, organ function, and drug interactions, genetic factors are often associated with drug response variability. This variability can occur due to single nucleotide polymorphisms (SNP) in protein-coding genes that play a role in bioavailability and drug response. Understanding of pharmacogenomics as the basis of individualized medicine aims to avoid adverse drug reactions and maximize drug effectiveness. The existence of genetic variation allows the drug response between individuals to be different. Pharmacogenomics provides important information in individual-based medicine so that it can predict the existence of a population that can respond well to certain drugs and a population that has a higher risk of adverse drug reactions. Implementation of individual treatment can optimize treatment in patients because the dose of treatment and therapeutic options have been adjusted based on individual genetic characteristics.
Single nucleotide polymorphism of AGT rs699 in the pathogenesis of hypertension and ACE inhibitors response: a narrative review Hartienah, Septiayu Dwi; Ikawati, Muthi'; Zullies Ikawati
Indonesian Journal of Pharmacology and Therapy Vol 5 No 2 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.9395

Abstract

Hypertension is a chronic cardiovascular disease that affects more than one billion people in the world. Angiotensinogen in the renin-angiotensin-aldosterone system (RAAS) is the main precursor encoded by angiotensinogen (AGT) gene and plays an important role in the development of hypertension. Single nucleotide polymorphism (SNP) of AGT gene is thought related to the pathogenesis of hypertension and angiotensinogen levels in plasma that may affect response to ACE inhibitors. This article reviewed the association of SNP AGT rs699 with the pathogenesis of hypertension and ACE inhibitors response. A total of 14 articles published from 1995 to 2023 were collected from databases including NCBI, Google Scholar, PubMed and Science Direct. Several studies in different populations have been conducted and showed various results. The T allele or TT genotype of AGT rs699 was associated in the pathogenesis of hypertension. However, the association between AGT rs699 and ACE inhibitor response shows inconsistent results, thus further research is needed.
Edukasi Period After Opening (PAO) Skincare, Cantik Sehat dengan Produk Aman Pada Siswa/i SMPN 10 Samarinda Candrakanti, Bratandari Hana; Lailatul Alivia; Aditya Fridayanti; Dathin Aulia Delarosa; Septiayu Dwi Hartienah; Nur Zakiyah Darajat
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 4 (2025): Oktober-Desember 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i4.13176

Abstract

The use of skincare products among adolescents is increasing, yet it is often not accompanied by adequate knowledge regarding safety and proper usage. One important aspect that is frequently overlooked is the period after opening, which determines the safe duration of product use after the packaging is opened. This issue may lead to health risks such as irritation, infection, and reduced skin quality if products are used beyond the recommended period. This activity aimed to improve students’ understanding of the period after opening, its difference from the expiration date, and the importance of selecting safe and authorized products. The method included health education through counseling, distribution of fan-shaped leaflets, question-and-answer sessions, and interactive games, followed by pre-test and post-test assessments involving 38 students of SMP Negeri 10 Samarinda. The analysis showed an increase in the average knowledge score from 11.34 in the pre-test to 15.21 in the post-test, with a paired t-test result indicating a significance value of 0.000 (p < 0.05), demonstrating a significant difference before and after the education. The majority of students who initially had a moderate level of knowledge improved to a good category after the intervention. In conclusion, education on the period after opening and safe use of skincare products proved effective in enhancing students’ knowledge and critical awareness, thereby serving as a preventive effort to protect adolescent skin health.
Co-Authors Aditya Fridayanti Candrakanti, Bratandari Hana Dathin Aulia Delarosa Hartati Mahmuda Hartati Mahmuda Ikawati, Muthi' Lailatul Alivia Nova Satriyani Nova Satriyani Nur Zakiyah Darajat