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All Journal Jurnal Abdimas Lamin Journal of Pharmaceutical (JOP)
Novia Ariani Dewi
Universitas Jenderal Achmad Yani Yogyakarta
Humanities Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health

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Hubungan Potensi Interaksi Obat Antihipertensi terhadap Luaran Klinis Pasien Lansia Ayu Waningsih; Lutfi Hidiyaningtyas; Novia Ariani Dewi
JOURNAL OF PHARMACEUTICAL (JOP) Vol. 3 No. 2 (2025): Journal of Pharmaceutical (JOP)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) UNIVERSITAS JENDERAL ACHMAD YANI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jop.v3i2.1673

Abstract

Background: The prevalence of hypertension increases with advancing age. Data from the 2018 Indonesian Basic Health Research (Riskesdas) indicates that hypertension is a common condition among the elderly. Physiological changes, along with alterations in pharmacokinetics, pharmacodynamics, and a higher likelihood of comorbidities, contribute to an increased number of medications consumed by elderly patients. This condition may raise the risk of drug interactions, potentially affecting clinical outcomes. Objective: To determine the association between the potential for antihypertensive drug interactions and clinical outcomes in elderly patients. Methods: This study was an analytical observational study with a retrospective design and purposive sampling technique. A total of 92 patients were included in the study. The research was conducted in the outpatient department of a hospital in Yogyakarta using medical record data from elderly hypertensive outpatients. Drug interactions were analyzed using the drugs.com application, and the association between potential antihypertensive drug interactions and clinical outcomes was analyzed using the chi-square test. Results: Most elderly hypertensive patients were female (65.2%) and had comorbidities or complications (78.3%). The majority of patients received combination therapy (65.2%). Potential drug interactions were identified in 78.3% of patients, with 80.5% classified as moderate in severity and 80.5% involving pharmacodynamic mechanisms. The chi-square test showed a p-value of 0.445, indicating no significant association between the potential for antihypertensive drug interactions and clinical outcomes. Conclusion: There is no significant association between the potential for antihypertensive drug interactions and clinical outcomes in elderly patients
Penguatan Literasi Kesehatan Lansia melalui Edukasi Pencegahan Asam Urat di LKS Cempaka Bantul Dwi Larasati; Bingar Hernowo; Novia Ariani Dewi; Arina Titami; Dianita Febrina Leswara
Jurnal Pengabdian Masyarakat Lamin Vol 5, No 2 (2026)
Publisher : Fakultas Ekonomi dan Bisnis Universitas 17 Agustus 1945 Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31293/jpml.v5i2.9668

Abstract

Peningkatan prevalensi asam urat pada kelompok lanjut usia menjadi salah satu permasalahan kesehatan yang memerlukan upaya promotif dan preventif melalui peningkatan literasi kesehatan. Rendahnya pengetahuan mengenai faktor risiko, gejala, pencegahan, serta pengelolaan asam urat dapat memengaruhi perilaku kesehatan lansia dalam menjaga kualitas hidupnya. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memperkuat literasi kesehatan lansia melalui edukasi pencegahan asam urat di LKS Cempaka Bantul. Metode pelaksanaan meliputi penyuluhan kesehatan menggunakan media presentasi dan leaflet, penyampaian materi secara interaktif, diskusi, serta evaluasi pemahaman peserta melalui pretest dan posttest. Sasaran kegiatan adalah lansia yang menjadi binaan LKS Cempaka Bantul. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan peserta mengenai pengertian asam urat, faktor risiko, tanda dan gejala, pola makan rendah purin, pentingnya aktivitas fisik, serta upaya pencegahan kekambuhan. Peserta juga menunjukkan antusiasme yang tinggi selama sesi diskusi dengan kemampuan yang lebih baik dalam mengidentifikasi perilaku hidup sehat untuk mengurangi risiko peningkatan kadar asam urat. Kegiatan edukasi ini terbukti efektif dalam meningkatkan literasi kesehatan lansia dan diharapkan dapat mendorong penerapan perilaku pencegahan asam urat secara mandiri sehingga berkontribusi terhadap peningkatan kualitas hidup pada kelompok lanjut usia
Co-Authors Ayu Waningsih Bingar Hernowo Dwi Larasati Leswara, Dianita Febrina Lutfi Hidiyaningtyas Titami, Arina