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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Berita Kedokteran Masyarakat Jurnal Pranata Biomedika
Tjitradinata, Cynthia
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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The Difference between Coagulation Profile and Fibrinolysis in Acute and Chronic Leukemia Patients Limijadi, Edward Kurnia Setiawan; Devi, Wivina Riza; Tjitradinata, Cynthia
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 2 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i2.2331

Abstract

The incidence of acute and chronic leukemia has been increasing for years resulting in many complications, one of them being hypercoagulability. Evaluation can be conducted using coagulation testing, including PT, aPTT, and fibrinogen levels, as well as fibrinolysis assays, such as D-dimer levels. Studies about these parameters between acute and chronic leukemia in the first diagnosis of leukemia need to be evaluated. This study aimed to evaluate the difference in coagulation and fibrinolysis profiles between acute and chronic leukemia. This study was a cross-sectional observational analysis of 34 acute and chronic leukemia patients in Ulin Government Hospital, Banjarmasin from October 2019 to February 2020. PT, aPTT, fibrinogen level, and D-dimer were analyzed on COA Lab 1000. Independent T-test and Mann-Whitney test were used to analyze data. The test results of PT, aPTT, fibrinogen, and D-dimer levels, for acute and chronic leukemia, were 13.96±1.86 vs. 16.73±4.74 seconds (p=0.029); 39.63±2.43 vs. 45.87±13.98 seconds (p=0.154); 286,18±180,58 vs. 328,81±150,63 mg/dL (p=0.459); and 746±3.392 vs. 1,466.56±445,86 µg/L (p=0.731), respectively. Significant differences were found in Prothrombin Time (PT) between acute and chronic leukemia patients, while no notable distinctions were observed in activated Partial Thromboplastin Time (aPTT), fibrinogen levels, or D-dimer levels.
Erratum to “The Difference between Coagulation Profile and Fibrinolysis in Acute and Chronic Leukemia Patients”[Published Issue of Indonesian Journal of Clinical Pathology and Medical Laboratory March 2025, 31(2) : p. 136] Limijadi, Edward Kurnia Setiawan; Devi, Wivina Riza; Tjitradinata, Cynthia
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 32 No. 1 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v32i1.2873

Abstract

This erratum is to explain a typographical error in Table 2 occurred in the published issue of Indonesian Journal of Clinical Pathology and Medical Laboratory Volume 31, Number 2 in March 2025, pages 136. The error was in writing the Fibrinogen level which should be a period, not a comma and D-dimer level in the table, which should be a comma, not a period.
Association between cholesterol and blood pressure examination in Sampangan, Semarang City: a preliminary study Christyana, To Lidwina Prillya Indra; Riwanto, Ignatius; Sebong, Perigrinus H; Sutanto, Eviana Budiartanti; Ernestia, Henrita; Tjitradinata, Cynthia; Kristanti, Alberta Widya
BKM Public Health and Community Medicine Vol 39 No 12 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v39i12.9841

Abstract

Purpose: This study aims to determine the baseline prevalence and association between blood pressure and cholesterol examination. Method: This preliminary study used a cross-sectional design to analyze the secondary blood pressure and cholesterol levels data in the Sampangan sub-district, Semarang City. The total sampling technique covered those enrolled in the metabolic syndrome screening from January to April 2023. The logistic regression test was used in data analysis. Results: 58 respondents took blood pressure checks, while only 40 had cholesterol checks. The probability of males getting changes in cholesterol levels was higher than that of females (OR = 8.69; p-value = 0.01). However, neither (female nor male) had a significant relationship, and there was no difference in the chances of changes in blood pressure (OR = 1.43; p = 0.72). Respondents above 60 years had a significant association with changes in blood pressure compared to those under 60 years (OR = 0.09; p = 0.007). Conclusion: This study revealed males of a certain age experience higher changes in cholesterol levels compared to females. People over 60 years old tend to have higher blood pressure compared to those under 60 years old. These findings propose an outreach strategy for health screening for patients with limited mobility, transportation access, and finances for routine checkups at public or government healthcare facilities.
CORRELATION BETWEEN HEMOGLOBIN LEVEL AND LOW BIRTH WEIGHT AMONG PREGNANT WOMEN IN MANOKWARI, WEST PAPUA Tjitradinata, Cynthia; Setiawan, I Edward Kurnia; Santoso, Ferry; Susianto, Indra Adi; Maya, Tiovani; Sutanto, Eviana Budiartanti; Sebong, Perigrinus Hermin
Jurnal Pranata Biomedika Vol 5, No 1: Maret 2026
Publisher : Universitas Katolik Soegijapranata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24167/jpb.v5i1.15238

Abstract

Introduction: Birth weight and its related maternal factors have significantly affected health throughout an individual’s life, particularly in western Indonesia. This study aims to reveal the effect of maternal anemia on low birth weight among newborns in General Hospital.Methods: A formative study was conducted from October to December 2023 in Manokwari, West Papua Province, Indonesia. We used secondary data from the birth cohort register 2022, including maternal socio-demographic information, health-related factors, antenatal visit details, and neonatal birth outcomes.Results: Pregnant women who give birth have an average gestational age of 28.80 (±1.08). The average hemoglobin level among pregnant women is 10.25 (±2.12), and the average newborn birth weight is 2932.9 (±447.1). Maternal age, educational status, employment status, infant gender, gestational age, and comorbidities do not correlate with birth weight. In contrast, hemoglobin levels with birth weight have a significant relationship between maternal hemoglobin levels and newborn birth weight.Conclusion: The study revealed that mothers with low hemoglobin levels are significantly associated with low birth weight among newborns at Manokwari Regional Hospital, West Papua. Future studies should be adjusted to explain pregnant women's iron levels and nutrition intake.
PENDAMPINGAN IBU HAMIL RISIKO TINGGI DI PUSKESMAS NGEMPLAK SIMONGAN, SEMARANG. Ida, William Adisaputra; Allobua, Cyntia Grace; Redinka, Skolastika Bena; Jazzyca, Gloria Serena; Tjitradinata, Cynthia
Jurnal Pranata Biomedika Vol 3, No 2: September 2024
Publisher : Universitas Katolik Soegijapranata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24167/jpb.v3i2.12323

Abstract

Hasil Long Form SP2020 (sensus penduduk 2020) menunjukkan Angka Kematian Ibu di Indonesia sebesar 189/100.000 yang artinya terdapat 189 kematian perempuan pada saat hamil, saat melahirkan atau masa nifas per 100.000 kelahiran hidup. Kehamilan dengan risiko tinggi merupakan penyebab utama tingginya angka kematian ibu. Ibu hamil dengan risiko tinggi memerlukan perhatian khusus untuk memastikan kehamilan dan kelahiran yang sehat. Puskesmas sebagai faskes menerapkan beberapa program pendampingan ibu hamil risiko tinggi sebagai upaya untuk menekan angka kematian ibu. Analisis ini bertujuan untuk mengetahui dampak yang diberikan oleh pelaksanaaan program pendampingan ibu hamil risiko tinggi di Puskesmas Ngemplak Simongan pada tahun 2023. Penelitian ini menggunakan pendekatan kualitatif dengan jenis observational preliminary study, data diperoleh dengan mewawancarai petugas kesehatan di Puskesmas Ngemplak Simongan serta analisis dokumen terkait. Hasil dari penelitian ini adalah pendampingan ibu hamil risiko tinggi di Puskesmas Ngemplak Simongan dilakukan dengan kunjungan ke rumah ibu hamil dan nifas oleh petugas kesehatan serta pemberian makanan tambahan (PMT) untuk ibu hamil kurang energi kronik dan anemia yang dilakukan sepanjang bulan Januari s/d Desember 2023. Pengawasan PMT mencapai target sedangkan program kunjungan masih belum mencapai target. Dapat disimpulkan bahwa pelaksanaan program pendampingan ibu hamil risiko tinggi di Puskesmas Ngemplak Simongan sudah terlaksanakan namun belum mencapai target. Penekanan angka kematian ibu di Puskesmas Ngemplak Simongan masih belum mencapai target 0 kematian. Kami merekomendasikan Puskesmas Ngemplak Simongan untuk mempertimbangan rekomendasi kami untuk program kegiatan tahun 2024. Penelitian ini memiliki keterbatasan waktu dan jumlah data yang dapat dianalisis, penelitian berikutnya sebaiknya dilakukan dengan data yang lebih lengkap.
Co-Authors Adi Susianto, Indra Allobua, Cyntia Grace Christyana, To Lidwina Prillya Indra Devi, Wivina Riza Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Ernestia, Henrita Ida, William Adisaputra Ignatius Riwanto, Ignatius Jazzyca, Gloria Serena Kristanti, Alberta Widya Maya, Tiovani Redinka, Skolastika Bena Santoso, Ferry Sebong, Perigrinus H Sebong, Perigrinus Hermin Setiawan, I Edward Kurnia Sutanto, Eviana Budiartanti