arrahman, ikhsan nazar
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Edukasi Bijak Berswamedikasi Pada Siswa Sekolah Menengah Atas di Kecamatan Rajeg, Kabupaten Tangerang, Banten arrahman, ikhsan nazar; Ul’Aufa, Rangga; Wulandari, Retno; Ayu, Restu; Musana, Rendika Hasanil; Sulis, Pretty Ananda
Jurnal Pengabdian Harapan Ibu (JPHI) Vol. 7 No. 1 (2025): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/jphi.v7i1.973

Abstract

Self-medication is an effort to treat symptoms and/or minor illnesses, such as pain, fever, dizziness, cough, flu, diarrhea, constipation, or skin diseases. However, as time goes by, the level of abuse of self-medication drugs is increasing, especially among adolescents. This community service aims to improve the knowledge of high school students in Rajeg District, Tangerang Regency, Banten Province regarding self-medication activities. This community service is pre-experimental semi-quantitative with a pre-test & post-test study design. Sampling used the quota sampling technique with a sample size of 90 respondents. Before the intervention, 90% (n=81) of male respondents stated that they did not or did not understand much and 10% (n=9) of female respondents stated that they did not understand or did not understand enough regarding self-medication practices. After the intervention, there was an increase in the understanding of respondents. As many as 17.8% (n=16) of male respondents stated that they still did not understand self-medication, in female respondents the increase in understanding with the highest percentage was understanding 37.8% (n=34). The conclusion, education of wise self-medication can increase students' knowledge in self-medication activities.
Asam mefenamat Efek Rekristalisasi Konvensional dan Dengan Bantuan Ultrasonik terhadap Karakteristik Kristal Asam Mefenamat Rasydy, La Ode Akbar; Damayanti, Hilda; Femalda, Adefia; Yuniarto, Ari; Arrahman, Ikhsan Nazar; Wahid, Rifki Saldi A.
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 12 No. 1 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v12i1.17164

Abstract

Mefenamic acid is classified as a Biopharmaceutical Classification System (BCS) Class II drug. Crystallisation techniques can significantly influence the critical properties of mefenamic acid crystals, an essential consideration in the pharmaceutical industry. This study investigates the effect of recrystallisation on the morphology and particle size of mefenamic acid crystals using ethyl acetate as the solvent.  Recrystallisation was conducted using both conventional and ultrasonic-assisted methods. The yield was calculated, and characterization was performed to determine the crystal properties, shape, and particle size using polarized microscopy, X-ray Diffraction (XRD), and Fourier Transform Infrared Spectroscopy (FTIR). The results showed that conventional recrystallisation yielded 25.078%, while ultrasonic-assisted recrystallisation at 50 W, 60 W, 70 W, and 80 W yielded 43.47%, 47.71%, 51.90%, and 50.20%, respectively. Skewness and kurtosis values for the average crystal length and width indicated a normal distribution. XRD analysis revealed that the diffraction peak intensity of conventionally recrystallised crystals became narrow. In contrast, the diffraction peak intensity of ultrasonically assisted crystals broadened. FTIR results demonstrated that the recrystallisation process did not alter the fundamental chemical structure of mefenamic acid. Recrystallisation methods influence crystal shape and size, with ultrasonic-assisted techniques producing crystals of smaller average size than those obtained through conventional methods.