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All Journal JURNAL FARMASIMED (JFM) JPS (Jurnal Pharma Saintika) Makassar Natural Product Journal MPSJ
Risda Waris
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Health Professions Medicine & Pharmacology

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STANDARDISASI EKSTRAK ETANOL BIJI BAGORE (Caesalpinia crista L.). Ardiansa Ardiansa; Rezki Amriati Syarif; Risda Waris
Makassar Natural Product Journal (MNPJ) Oktober 2024
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Bagore plant (Caesalpinia crista L.) belongs to the tribe Leguminosae and grows wild on the coast. Standardization is important to guarantee potency uniformity benefits by ensuring the concentration of active ingredients through qualitative analysis of secondary metabolites, ensuring the safety and stability aspects of extracts and increasing the economic value of extracts by various analyses such as specific and non-specific parameters. This study aims to standardization bagore seed extract (Caesalpinia crista L.) and determine the value of specific and non-specific parameters of. Samples were obtained from Binuang District, Polewali Mandar Regency, West Sulawesi Province, macerated with 96% ethanol then standardized with specific and non-specific parameters. The results of the study obtained specific parameter values as follows; organoleptic tests obtained extracts in the form of viscous, light brown in color, characteristic smell and very bitter taste; The content of soluble compounds in water is 14.361%; the content of soluble compounds in ethanol is 15.708%; positively contains flavanoid compounds, alkaloids and saponins; and the value of non-specific parameters as follows: drying shrinkage which is 0.439%; specific weight of 0.859 grams; moisture content of 2.589%; total ash content of 4.216%, insoluble ash content of acid which is 0.630%; The mold number is < 1.0 x 101 colonies/ml and the yeast is < 1.0 101 colonies/ml; lead metal contamination (Pb) is 0.003 g / g and cadmium (Cd) is 0.01 g / g. Research shows bagore seed extract (Caesalpinia crista L.) provides results according to the general standard parameters of medicinal plant extracts. Keyword : Bagore seed, Caesalpinia crista L., standardization, spesific parameters, non-spesific parameters.
STUDI KOMPARASI AKTIVITAS ANTIRADIKAL BEBAS ANTARA EKSTRAK METANOL DAUN DAN KULIT KAYU TUMBUHAN KEDONDONG PAGAR (Lannea coromandelica (Houtt.) Merr) DENGAN METODE PEREDAMAN SENYAWA 1,1-DIPHENYL -2-PICRYLHYDRAZIL (DPPH) Asma Alwi; Ahmad Najib; Risda Waris
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 1 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Lannea coromandelica (Houtt.) Merr is one of the plants that hast he potential to have free antiradical activity. The research aimed to compare the free antiradical activity of methanol extract of the bark and leaves of Lannea coromandelica (Houtt.) Merr using the free radical reduction method 1.1 diphenhyl-2-picrylhydrazil (DPPH). The bark nd the leaves extract of the tree were obtained by maceration using methanol. The methanol extract preliminary tests were conducted by TLC using n-hexane: ethyl acetate (9 : 1) and ( 7: 3). The positive results for free antiradical aoctivity marked with purple to yellow spots after DPPH spraying was obtained. The thick bark and leaves extract were then quantitatively tested for free antiradical activity to obtain lC50 values using spectrophotometry at the maximum wavelength of 516 nm. The results of data analysis showed that methanol extract of its bark and leaves had lC50 of 20.778 µg / mL and 19.819 µg / mL, with ascorbic acid as a comparison having an lC50 value of 6.816 µg / mL. So it can be concluded that the methanol extract of the leaves of"Lannea coromandelica (Houtt) Merr has stronger anti-radical activity than its bark.
Pharmacognostic Identification and Specific Quality Parameters of Blue Porterweed (Stachytarpheta jameicensis) Leaf Extract from Enrekang Regency, South Sulawesi amin, asni; Risda Waris; Noer Kurnia; Nur Fadilla
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2477

Abstract

The leaves of Blue Porterweed (Stachytarpheta jamaicensis) are commonly found in Enrekang district and used as medicinal plants. Its pharmacological effects have been tested invitro and invivo. However, data on the quality of this extract is still unpublished. This study was conducted to identify the pharmacognostic and specific quality parameters of horse whip leaf extract from Enrekang district. The research method is laboratory experimental. Pharmacognostic identification was carried out by identifying plant morphology, macroscopic test of simplisia, and identification of chemical content by Thin Layer chromatography (TLC). The extract obtained from maceration using 70% ethanol and then determined its specific parameters including organoleptic tests, extract identity parameters, soluble extract content in certain solvents. The results of pharmacognostic identification that have been carried out show that horse whip is a shrub, 50 cm-1.2 m high, taproot, lanceolate leaf, serrated edges, pinnate leaf repetition and belongs to the Verbenaceae family, and the TLC results of the extract show the presence of alkaloid, phenol, and flavonoid compounds. The identity name of the extract is Stachytarpetae Folium Extractum, black brown in colour, thick extract texture, slightly bitter taste, and weak odour. Test results of water soluble extract content = 14.96% and ethanol soluble extract content = 15.23%. Conclusion: Data on specific quality parameters of blue porterweed leaf extract will be a reference for the manufacture of standardised herbal medicine.
OPTIMASI WAKTU EKSTRAKSI DAUN PECUT KUDA (Stachytarpheta jamaicensis) DENGAN METODE DIGESTI DAN NILAI RENDEMEN EKSTRAKNYA Amin, asni; Risda Waris; Devita
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.76

Abstract

Abstract: Extraction of natural medicines can not only extract chemical components from the sample, but also be a guideline in determining yield value (extract). One of the extraction methods is digestion. The purpose of this research is to optimize the digestion extraction time and determine the high yield value of blue porterweed (Stachytarpheta jamaecensis) leaf extract obtained. Horse whip leaf extract (EPK) was obtained by digestion at 2 (D1), 4 (D2) and 6 (D3) hours at 40oC using 70% ethanol solvent, the ethanol extract was evaporated with a rotary vaccum-evaporator 10 degrees below its boiling point to become a thick extract. Each extract was weighed and the yield value was calculated. The results of digestion extraction obtained the yield value of EPK in D1 = 12,4%; EPK in D2 =  15,36%, and EPK in D3 = 12.3%. Extraction optimization using the digestion method can be used as a reference for the development of herbal medicines for  traditional medicine manufacturers.
Co-Authors Ahmad Najib Ardiansa Ardiansa Asma Alwi Asni Amin Devita Noer Kurnia Nur Fadilla Rezki Amriati Syarif