Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Indonesian Journal of Global Health research BIOGENIC: Jurnal Ilmiah Biologi
Banowati, Annisa
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
UJI AKTIVITAS HEPATOPROTEKTIF KOMBINASI MADU DAN JINTAN HITAM TERHADAP KADAR SGOT-SGPT TIKUS PUTIH YANG DIINDUKSI MINUMAN BERSODA Sayekti, Fitria Diniah Janah; Mukharomah, Katrine Adiansyah Dwi; Andriansyah, Maulana Fikri; Anggraini, Tiara; Banowati, Annisa
BIOGENIC : Jurnal Ilmiah Biologi Vol 1 No 2 (2023): BIOGENIC: Jurnal Ilmiah Biologi
Publisher : Program Studi Biologi UNARS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/biogenic.v1i2.3771

Abstract

Minuman ringan berkarbonasi dapat berperan sebagai toksin yang menyebabkan kerusakan fungsi pada hepar. Senyawa atau produk yang dapat berperan sebagai pelindung kerusakan hepar diantaranya adalah madu dan jintan hitam. Kombinasi minyak jintan hitam dan madu sebagai agen hepatoprotektif dimungkinkan terjadi peningkatan kapasitas antioksidan 3-4 kali lipat dibandingkan biji jintan hitam atau madu saja. Penelitian ini bertujuan untuk mengetahui efek pemberian madu dan jintan hitam sebagai hepatoprotektor terhadap kadar sgot dan sgpt tikus wistar yang diinduksi minuman bersoda. Penelitian ini menggunakan desain eksperimental dengan hewan coba sebanyak 6 kelompok dimana setiap kelompok terdiri dari 4 ekor tikus putih. Sampel yang digunakan adalah 24 sampel plasma darah. Metode pemeriksaan yang digunakan adalah metode Spektrofotometri. Berdasarkan hasil penelitian dapat diketahui bahwa kombinasi antara madu dengan jintan hitam dengan konsentrasi 75% dapat menurunkan kadar SGOT-SGPT pada tikus putih yang diinduksi minuman bersoda. Kata Kunci: Minuman karbonasi, jintan hitam, madu, hepatoprotektif, SGOT-SGPT
Hepatoprotective Effect of Honey and Black Cumin Combination Against Soft Drink-Induced Rattus norvegicus Liver Based on Histopathological Features Banowati, Annisa; Sayekti, Fitria Diniah Janah
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.4168

Abstract

Carbonated soft drinks are drinks that can cause damage to the liver if consumed excessively. The combination of honey and black cumin as an antioxidant agent has hepatoprotective and antioxidant effects with a capacity of 3-4 times compared to honey or black cumin seeds alone. The aim of this research was to determine the effect on macroscopic and microscopic observations of the liver of Rattus norvegicus given a combination of honey and black cumin in graded doses, namely concentrations of 25%, 50% and 75% after being induced by soft drinks and the damage that occurred when given in doses and the specified time. This research was carried out experimentally at the Cytohistotechnology Laboratory Sekolah Tinggi Ilmu Kesehatan Nasional. The research was divided into 6 groups, namely 3 control groups and 3 treatment groups. The results of macroscopic observations showed differences in colour, size, fatty and similarities in liver texture. The results of microscopic observations showed normal cells and damage such as hydropic degeneration, parenchymatous degeneration, pyknosis necrosis, karyorrhexic necrosis, and karyolysis necrosis. The results of the test using One Way ANOVA and followed by Post Hoc Duncan can be concluded that giving a combination of honey and 75% black cumin as much as 2 mL/200 gr weight of rats can have a protective effect on macroscopic and microscopic examination of the liver of Rattus norvegicus after being induced by soft drinks.
Co-Authors Andriansyah, Maulana Fikri Mukharomah, Katrine Adiansyah Dwi Sayekti, Fitria Diniah Janah Tiara Anggraini