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Pengaruh Ekstrak Daun Buncis (Phaseolus vulgaris L.) Terhadap Jumlah Fibroblast Kulit dalam Penyembuhan Luka Bakar Ningsih, Putri Satria; Muchtar, Muhammad Arafat; Putri, Riri Virzan
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 2 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i2.765

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun buncis (Phaseolus vulgaris L.) terhadap peningkatan jumlah fibroblas pada kulit selama proses penyembuhan luka bakar. Penelitian ini menggunakan model tikus putih jantan galur Wistar yang diinduksi luka bakar. Tikus dibagi menjadi beberapa kelompok perlakuan, yaitu kelompok kontrol negatif, kelompok kontrol positif, dan kelompok perlakuan dengan berbagai dosis ekstrak daun buncis. Ekstrak dioleskan secara topikal selama periode tertentu. Hasil penelitian menunjukkan bahwa pemberian ekstrak daun buncis secara signifikan meningkatkan jumlah fibroblas dibandingkan dengan kelompok kontrol negatif. Hal ini menunjukkan potensi ekstrak daun buncis sebagai agen penyembuhan luka bakar melalui mekanisme stimulasi proliferasi fibroblas. Penelitian ini memberikan kontribusi yang signifikan terhadap pengembangan terapi alami untuk penyembuhan luka bakar.
Gastritis in medical students: An analysis of contributing factors Kesuma, Farah Shyfa; Girsang, Ermi; Nasution, Ali Napiah; Putri, Riri Virzan; Anggraini, Tri Lidya
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.6363

Abstract

Gastritis, defined as inflammation of the stomach lining, can arise from various factors, including Helicobacter pylori infection, stress, poor dietary habits, and the use of certain medications. Medical students represent a population particularly susceptible to gastritis due to high academic pressure, irregular eating patterns, and smoking habits. This study aimed to analyze the risk factors for gastritis among medical students at Prima Indonesia University. This study employed a cross-sectional design involving 123 medical students. Data were collected through questionnaires, and statistical analysis was performed using SPSS version 27. The majority of the study subjects were 21 years old (61.8%) and female (74.8%). Irregular eating habits (82.1%), coffee consumption (74%), and academic stress (79.7%) were prevalent among the subjects. More than half of the subjects had a history of gastritis (57.7%). The risk factors significantly associated with gastritis included female sex (OR=2.362; 95% CI: 1.030-5.414), irregular eating patterns (OR=3.707; 95% CI: 1.385-9.918), coffee consumption (OR=2.569; 95% CI: 1.126-5.861), and academic stress (OR=3.062; 95% CI: 1.227-7.638). Age did not significantly affect the risk of gastritis. Females were found to be more susceptible to gastritis than males, possibly due to hormonal influences and lifestyle factors. Irregular eating patterns and coffee consumption increased the risk of gastritis; however, smoking habits did not show a significant association. Academic stress was identified as an important risk factor, as it can increase gastric acid production. The risk factors significantly associated with gastritis among medical students were female sex, irregular eating patterns, coffee consumption, and academic stress.
Application of Clitoria ternatea L. Flower Extract Lotion in Preventing the Decrease in Collagen and Epidermis Thickness in Wistar Rats Skin Given Ultraviolet-B Rays Gracela, Ira; Girsang, Ermi; Nasution, Ali Napiah; Yuliansyah, Jeri; Putri, Riri Virzan
Jurnal Penelitian Pendidikan IPA Vol 11 No 3 (2025): March
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i3.10947

Abstract

Exposure to ultraviolet-B (UV-B) light contributes to a decrease in skin collagen levels, which can cause premature aging. This study aims to evaluate the effectiveness of telang flower (Clitoria ternatea L.) extract lotion in maintaining collagen levels and epidermal thickness of UV-B-exposed rat skin. A total of 30 Wistar male white rats (200-250 g) were divided into six treatment groups: negative control (distilled water), positive control (Vaseline), and four treatment groups of telang flower extract lotion with concentrations of 0.2, 0.5, 0.75, and 1%. Mice were exposed to UV-B light (311 nm, 70 mJ/cm² per session) for 14 days with a total dose of 420 mJ/cm². The lotion was applied twice daily, before and after UV-B exposure. Evaluation was performed by measuring collagen content and epidermal thickness using histology staining. Statistical analysis used One-Way ANOVA or Kruskal-Wallis if assumptions were not met. The results showed that the treatment group with telang flower extract significantly increased collagen content and epidermal thickness compared to the negative control (p < 0.05), with a dose of 0.5% showing the highest effectiveness. In conclusion, telang flower extract lotion has potential as a photoprotective agent against UV-B-induced skin damage.