Article Per Year (5 Year)
p-Index From 2020 - 2025
0.778
P-Index
This Author published in this journals
All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Journal of Health (JoH) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Indonesian Journal for Health Sciences (IJHS) Journal of Fundamental and Applied Pharmaceutical Science
Deka Prismawan
Universitas Katolik Indonesia Atma Jaya
Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
Evaluasi Kandungan Glukosa Dan Indeks Glikemik Beberapa Sumber Karbohidrat Dalam Upaya Penggalian Pangan Ber-Indeks Glikemik Rendah Nuzul Wahyuning Diyah; Aprilia Ambarwati; Gita M. Warsito; Greta Niken; Eriza T. Heriwiyanti; Rany Windysari; Deka Prismawan; Robi'atul F. Hartasari; Purwanto Purwanto
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 3 No. 2 (2016): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (465.275 KB) | DOI: 10.20473/jfiki.v3i22016.67-73

Abstract

Pendahuluan: Berbagai penelitian menunjukkan bahwa diet makanan ber-Indeks Glikemik (IG) rendah mampu menurunkan resistensi insulin pada penderita Diabetes Mellitus. Masalah utama dalam diet pangan IG rendah adalah ketersediaan bahan pangan dengan IG rendah sementara makanan pokok sebagian besar penduduk Indonesia adalah nasi, yang tergolong pangan dengan IG tinggi.Tujuan: menentukan kandungan glukosa dan indeks glikemik beberapa bahan pangan sumber karbohidrat dari kelompok biji-bijian (beras merah, jagung, sorgum), umbi-umbian (singkong, bentul), buah-buahan (pisang kapok, pisang ambon, sukun), serta kacang-kacangan (kacang hijau, kacang merah), untuk memperoleh bahan pangan sumber karbohidrat ber-IG rendah sebagai pangan alternatif pengganti nasi dalam diet penderita Diabetes Mellitus. Metode: Kadar glukosa ditentukan dengan metode Luff-Schoorl dan penentuan indeks glikemik dilakukan menggunakan hewan coba kelinci terhadap pangan standar, glukosa 0.47 g/Kg berat badan. Sampel pangan uji diberikan dalam jumlah yang setara dengan kandungan glukosa dalam setiap pangan uji. Hasil: Kandungan glukosa yang ditetapkan sebagai gula pereduksi total dalam pangan uji bervariasi, bergantung pada karakter pati dalam pangan sumber karbohidrat. Semua pangan uji memiliki indeks glikemik yang lebih rendah dibanding nasi putih, tetapi singkong kukus dan bentul kukus masih tergolong pangan IG tinggi. Kesimpulan: Kecuali singkong dan bentul, semua pangan yang diuji adalah pangan sumber karbohidrat yang direkomendasikan untuk penderita diabetes.
The Effects of Heating Temperatures on Passion Fruit Juice's Ascorbic Acid and Total Phenol Levels Siswandi, Alodia Jeconiah; Prismawan, Deka; Kambira, Pretty Falena Atmanda
Journal of Fundamental and Applied Pharmaceutical Science Vol 4, No 1 (2023): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v4i1.18648

Abstract

The Passiflora edulis f. flavicarpa, a yellow passion fruit, is known for its distinctive aroma and tart flavor. The pulp of the yellow passion fruit can be used to make tea, jam, and syrup commercially. Commercial items are processed using oven heating, which involves prolonged exposure to high temperatures. As a result, fruit content, particularly water content, may alter. The benefit of reducing the water content is that less microbial growth medium means the product has a longer shelf life. However, fruit flesh’s nutritional composition will also change due to the ascorbic acid and phenolic compounds' thermolability and other factors. In this study, the yellow passion fruit pulp juice is heated in a controlled manner at 60°C, 70°C, and 80°C for 7 hours using an oven. The purpose is to assess changes in the amounts of ascorbic acid and total phenol that occurred. A paired T-test was used to assess the association between weight loss, ascorbic acid levels, and phenolic levels in the control and treatment groups. The amount of ascorbic acid was determined using the 2.6 dichloroindophenol titrimetry method, and the amount of phenol was determined using the Folin-Cioceltau method and UV-Vis spectrophotometry. According to this study, increasing the temperature to 60 °C or 80 °C significantly reduces weight and ascorbic acid levels. Also, the heating temperature unaffected the amount of phenol in each group.
Optimization of Sunscreen Cream Formulation Containing Ethanolic Extract of Avocado Leaves (Persea americana Mill.) or Mangosteen Rind (Garcinia mangostana L.) Combined with Octyl Methoxycinnamate: Optimasi Formula Krim Tabir Surya Mengandung Ekstrak Etanolik Daun Alpukat (Persea americana Mill.) atau Kulit Manggis (Garcinia mangostana L.) Kombinasi dengan Oktil Metoksisinamat Verda, Vanessia; Leonardo, William; Prismawan, Deka; Notario, Dion
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 9 No. 2 (2023): (October 2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2023.v9.i2.16083

Abstract

Background: Most sunscreens contain chemicals that can cause health and environmental problems. Natural actives can be an alternative to minimize the use of chemicals. Avocado leaves (Persea americana Mill.) and mangosteen peel (Garcinia mangostana L.) contain active compounds that have UV absorption. Objective: In this study, the optimal composition of a mixture of ethanol extracts of avocado leaves or mangosteen peel with octyl methoxycinnamate (OMC) was determined based on the Sun Protection Factor (SPF) and adhesive properties using Response Surface Methodology (RSM). Material and method: The optimal formula calculated with RSM was then made and underwent a series of tests, including a hedonic test with a scale of 0-9 on 30 respondents, a freeze-thaw stability test, and an accelerated stability test with the Arrhenius equation. Results: The RSM analysis showed that the optimal concentration of extract and OMC was 10% and 0.75% (avocado leaves) & 0.65% (mangosteen peel). The optimized formula resulted in adhesive properties and SPF of 7.41±0.03 and 16.52±0.16 (avocado leaves) & 7.43±0.04 and 15.84±0.15 (mangosteen peel) respectively. Both optimized formulations were physically stable against freeze-thaw and had a t90 of 29 minutes (avocado leaves) and 17 minutes (mangosteen peel). The average hedonic scale obtained was 7.8 (avocado leaves) and 7.9 (mangosteen peel), indicating that both optimized formulations were preferred by the respondents. Conclusions: The sunscreen formulation with an optimized combination of active ingredients from avocado leaf extract or mangosteen peel extract with OMC using RSM results in preparation with SPF value and physical properties that meet the requirements.
Aktivitas Antibakteri dari Sinularia sp. terhadap Escherichia coli dan Staphylococcus aureus: Meta-analisis dan Telaah Sistematis: Antibacterial Activity of Sinularia sp. Against Escherichia coli and Staphylococcus aureus: Meta-Analysis and Systematic Review Prismawan, Deka; Monika Arvia Chiara; Shannen Ivanka Gunardi; Karmill Trinanda; Robby Sutedjo; Michael, Michael
Journal of Health (JoH) Vol 12 No 1 (2025): Journal of Health (JoH) - January
Publisher : LPPM STIKES Guna Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30590/joh.v12n1.1094

Abstract

The Ocean covers more than 70% of Indonesian archipelago, providing various bioactive compounds with great potential, however, it is relatively underexplored Sinularia sp, a genus of soft corals, exists at the coral reefs of Indo-Pacific ocean. Several recent studies have shown that Sinularia sp. contains various types of secondary metabolites with antiviral, antibacterial, anticancer, and antimalarial properties. In addition, further exploration and discovery of novel antibacterials that are effective against wide spectrum of bacteria is of great interest, especially to combat the emerging antibiotic resistance. The aim of this study is to evaluate the potential of antibacterial activity from Sinularia sp against E. coli and S. aureus which in turn, may provide an alternative antibacterial to overcome the emerging antibiotic resistance. This study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement to measure the effect size of the antibacterial activity from Sinularia sp. against E. coli and S. aureus. Estimated value of the effect size obtained is 2.52 (CI 95% 0.98 to 4.06) and 5.97 (CI 95% 3.18 to 8.77) towards E. coli and S. aureus. When viewed as a whole, published data appears to show a positive antibacterial effect from Sinularia sp.
EFFECT OF EXTRACTION METHODS ON PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF BAJAKAH ROOT (Spatholobus littoralis) Agustin, Julia Then; Kambira, Pretty Falena Atmanda; Michael, Michael; Prismawan, Deka
Indonesian Journal of Health Science Vol 9 No 2 (2025): September
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/ijhs.v9i2.11683

Abstract

The Bajakah root (Spatholobus littoralis), a native plant of Kalimantan, is recognized for its phenolic content and antioxidant activity. This study aims to compare the effects of three extraction methods—maceration, soxhlet, and reflux—on the total phenolic content and antioxidant activity of Bajakah root extracts. The plant material was extracted using 96% ethanol, followed by phenolic content analysis via the Folin-Ciocalteu method and antioxidant activity evaluation using the DPPH assay. Results revealed that the reflux method produced the highest phenolic content (17.6 ± 0.1 mg GAE/g extract) and the strongest antioxidant activity (IC50 of 26 ± 1 µg/mL). The soxhlet method yielded a phenolic content of 17.4 ± 0.2 mg GAE/g extract with an IC50 of 30 ± 0 µg/mL, while maceration resulted in the lowest phenolic content (14.6 ± 0.7 mg GAE/g extract) and an IC50 of 34 ± 2 µg/mL. The heating processes involved in the reflux and Soxhlet methods likely facilitated the degradation of glycosides, thereby enhancing phenolic content. All methods demonstrated exceptionally strong antioxidant activity (IC50 < 50 µg/mL). This study underscores the significant influence of extraction methods on the phenolic quality and antioxidant capacity of Bajakah root extracts.
Co-Authors Agustin, Julia Then Aprilia Ambarwati Dion Notario Diyah, Nuzul Wahyuning Eriza T. Heriwiyanti Gita M. Warsito Greta Niken Kambira, Pretty Falena Atmanda Karmill Trinanda Leonardo, William Michael Michael Monika Arvia Chiara Rany Windysari Robby Sutedjo Robi'atul F. Hartasari Rony, Zahara Tussoleha Shannen Ivanka Gunardi Siswandi, Alodia Jeconiah Verda, Vanessia