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MIKROENKAPSULASI EKSTRAK FORMULA PEGAGAN-KUMIS KUCING-SAMBILOTO SEBAGAI INHIBITOR Angiotensin I Converting Enzyme SECARA In Vitro Rani, Ismarani; Pradono, Dyah Iswantini; Darusman, Latifah K
CEFARS : JURNAL AGRIBISNIS DAN PENGEMBANGAN WILAYAH Vol. 3 No. 1 (2011): CEFARS : JURNAL AGRIBISNIS DAN PENGEMBANGAN WILAYAH
Publisher : Fakultas Pertanian Universitas Islam 45 (UNISMA) Bekasi

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Abstract

Chitosan microencapsulation contained extract formula pegagan-kumis kucingsambiloto was resulted from ionic gelation process. Chitosan microencapsulation wasresulted by cleaning bath type of ultrasonication and homogenization methods. Optimum condition obtained at 2% of chitosan concentration (w/v) and 50 mL (v/v) of extract formula. The yields of chitosan microparticles was 64.24%. Characterization by SEM at 5000× magnification showed that the particle size of chitosan microparticles was not uniform. Chitosan microparticles without and contained extract formula had diameters between 0.40 μm-8.5 μm and 1 μm-6 μm, respectively. Each chitosan microparticles contained extract formula and extract formula had the ACE inhibitory activity of 78.41 %, and 75.73 %, respectively, while the captopryl as an positive control had ACE inhibitory activity of 75.24 %. Wave number peaks of chitosan spectrum was different with microparticles spectrum by using of FTIR analysis. Chitosan microparticles-sodium tripolyphosphate (STP) contained extract formula had absorbance bands of 1652.32 cm-1 (C=O) and 1565.63 cm-1 (C=C, aromatic group of benzene). New absorbance bands also appeared at wave numbers of 1153.82 cm-1 and 1154.66 cm-1 which showed absorbance band of P=O group from STP compound.
POTENSI SENYAWA TANNIN DALAM MENUNJANG PRODUKSI RAMAH LINGKUNGAN Rani, Ismarani
CEFARS : JURNAL AGRIBISNIS DAN PENGEMBANGAN WILAYAH Vol. 3 No. 2 (2012): CEFARS : JURNAL AGRIBISNIS DAN PENGEMBANGAN WILAYAH
Publisher : Fakultas Pertanian Universitas Islam 45 (UNISMA) Bekasi

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Abstract

Tannin is the compound astringent, bitter plant polyphenols that contain groups that can form a complex hydrocyls strong links with proteins and other macromolecules.Tannins are water soluble phenolic compounds having molecular weights between 500 and 3000 Da that can bind and precipitate or shrink protein.Tannin classified intohydrolyzable tannins and condensed tannins (proanthocyanidins). Dekstruction or modification of tannin has an important role in wood preservatives, heavy metal adsorbents, medicine, antimicrobials, etc.