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All Journal JURNAL FARMASIMED (JFM) Journal of Innovative and Creativity
Rahmat Hidayat
Universitas Duta Bangsa Surakarta
Education Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Social Sciences Other

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Formulasi dan Uji Mutu Fisik Sediaan Losion Kombinasi Infusa Daun Kelor (Moringa oleifera Lam.) dan Bunga Telang (Clitoria ternatea L.) Novita Silalahi; Annie Rahmatillah; Rahmat Hidayat
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.8212

Abstract

ABSTRACT Moringa leaves (Moringa oleifera Lam.) and butterfly pea flowers (Clitoria ternatea L.) contain flavonoid compounds that act as natural antioxidants capable of scavenging free radicals. This study aimed to formulate a lotion preparation containing a combination of moringa leaf and butterfly pea flower infusions and to evaluate the physical quality of the resulting formulation. Four lotion formulas were prepared, consisting of F0 as a positive control and F1–F3 with variations in the ratio of moringa leaf and butterfly pea flower infusions, namely F1 (2:2), F2 (3:1), and F3 (1:3). Physical quality evaluation included organoleptic test, pH measurement, spreadability, adhesiveness, viscosity, globule size, and centrifugation test. The results showed that all lotion formulas exhibited physical characteristics that met the quality requirements for topical preparations. Organoleptic evaluation indicated that F0 was white, F1 was bluish-green, F2 was green, and F3 was blue in color, with lotion form and strawberry odor. The pH values were 6.26 for F0, 6.37 for F1, 6.63 for F2, and 6.52 for F3. Spreadability ranged from 5–7 cm, adhesiveness was more than 4 seconds, and the average viscosity values were 4,024 cPs for F0, 2,124 cPs for F1, 2,921 cPs for F2, and 2,669 cPs for F3. The globule size was small and uniform, and the centrifugation test showed no phase separation. Keywords: Butterfly Pea Flowers, Moringa Leaves, Skin, Lotion, Physical Quality
Aktivitas Tonikum Infusa Bunga Telang (Clitoria ternatea L.) terhadap Mencit dengan Metode Natatory Exhaustion dan Induksi Tidur Eli Yuliana. H; Siwi Hastuti; Rahmat Hidayat
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.8214

Abstract

ABSTRACT Tonics are agents that can stimulate body activity, thereby delaying feelings of fatigue, lethargy, and exhaustion. This study aimed to determine the ability of butterfly pea flower infusion to increase swimming time and its potential effect on the sleep duration of mice, as well as to evaluate the relationship between dose variation and tonic effects. Butterfly pea flower contains secondary metabolites such as alkaloids and flavonoids, which are known to produce tonic effects. This experimental study used 25 mice as test animals, divided into five groups. The test groups consisted of a negative control (distilled water), a positive control (caffeine 100 mg), and butterfly pea flower infusion at doses of 10%, 20%, and 40%. The results showed that butterfly pea flower infusion exhibited tonic effects in both the natatory exhaustion and sleep induction methods. The 10% dose produced tonic effects of 38.99% ± 10.34% in the natatory exhaustion method and 17.72% ± 6.13% in the sleep induction method. The 20% dose resulted in tonic effects of 52.82% ± 7.39% and 39.38% ± 6.22%, respectively. The 40% dose produced the greatest tonic effect, with values of 79.53% ± 3.82% in the natatory exhaustion method and 59.55% ± 1.72% in the sleep induction method. Keywords: Butterfly Pea Flower, Infusion, Natatory Exhaustion, Sleep Induction, Tonic
Optimasi Nilai Sun Protection Factor (SPF) Ekstrak Daun Bayam Hijau (Amaranthus hybridus L.) Berdasarkan Variasi Pelarut Etanol 70% dan Aseton dengan Metode Spektrofotometri UV-Vis Tasya Aurelia; Rahmat Hidayat; Bagas Ardiyantoro
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.8293

Abstract

ABSTRACT Indonesia has high levels of ultraviolet (UV) exposure, which poses a risk of skin health problems. The use of sunscreen is necessary as a protective measure, but synthetic sunscreens can cause side effects, so natural alternatives are needed. Green amaranth leaves (Amaranthus hybridus L.) contain flavonoids that have the potential to absorb UV rays. This study aims to evaluate the sunscreen activity of green amaranth leaf extract using 70% ethanol and acetone solvents, determine the optimum Sun Protection Factor (SPF) value, and identify the most effective and efficient solvent. Extraction was performed using the maceration method, then the sunscreen activity was tested using UV-Vis spectrophotometry at a wavelength of 290–320 nm with concentration variations of 40, 60, 80, 100, and 120 ppm. The results showed that both extracts had sunscreen activity. The optimum SPF value was obtained at a concentration of 120 ppm, namely 70% ethanol extract 11,45 (maximum protection) and acetone extract 19,11 (ultra protection). Acetone was the most effective and efficient solvent in extracting UV-absorbing compounds. Keywords: 70% Ethanol, Acetone, Green Spinach Leaves (Amaranthus hybridus L.), SPF, Sunscreen
Comparison of the SPF Values of 70% and 96% Ethanol Extracts of Bandotan Leaves (Ageratum conyzoides L.) Using the UV-Vis Spectrophotometric Method Dewianisya Arifatussholiha; Annie Rahmatillah; Rahmat Hidayat
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/8gtb2161

Abstract

Indonesia, as a tropical country, has high exposure to ultraviolet radiation that can cause skin damage. Bandotan leaves (Ageratum conyzoides L.) contain flavonoids and tannins capable of absorbing UV radiation, thus having potential to be developed as a safer natural sunscreen agent. This study aimed to determine the Sun Protection Factor (SPF) values of 70% and 96% ethanol extracts of bandotan leaves using the UV-Vis spectrophotometric method and to evaluate the effect of different ethanol solvent concentrations on the SPF values of the extracts. The study used dried bandotan leaf simplicia extracted by maceration method with 70% and 96% ethanol. The obtained extracts were subjected to standardization and phytochemical screening. SPF values were determined in vitro using a UV-Vis spectrophotometer at a wavelength range of 290–320 nm with extract concentrations of 20, 40, 60, 80, and 100 ppm, and calculated using the Mansur method. The results showed that the SPF values of the 70% ethanol extract were 1.1550, 1.8349, 2.4004, 3.3868, and 4.5036, respectively, while the 96% ethanol extract produced SPF values of 1.0821, 2.0559, 2.9325, 3.8779, and 5.1098, categorized from no protection to moderate protection. The difference in ethanol solvent concentration (70% and 96%) had a significant effect on the SPF values of bandotan leaf extract (p < 0.05). Based on these findings, it can be concluded that the 96% ethanol extract of bandotan leaves (Ageratum conyzoides L.) is more effective than the 70% ethanol extract in producing photoprotective activity and therefore has potential to be developed as a natural ingredient in sunscreen formulations.
Co-Authors Annie Rahmatillah Bagas Ardiyantoro Dewianisya Arifatussholiha Eli Yuliana. H Novita Silalahi Siwi Hastuti Tasya Aurelia