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PENGARUH PROTEIN PILI Streptococcus Agalactiae TERHADAP EKSPRESI β-Defensin-2 PADA TUBA FALLOPI TIKUS PUTIH (Rattus novergicus) GALUR WISTAR Nur Rohmah Prihatanti; Hening Ryan Aryani; Istifadatul Ilmiya; Noorhamdani A.S.; Dwi Yuni Nur Hidayati
Jurnal Ilmiah Farmako Bahari Vol 12, No 1 (2021): Jurnal Ilmiah Farmako Bahari
Publisher : Fakultas MIPA Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jfb.v12i1.1001

Abstract

Salah satu infeksi pada organ genitalia wanita adalah infeksi tuba falopi. Infeksi tuba fallopi dapat disebabkan oleh Streptococcus agalactiae. Pencegahan infeksi yang disebabkan oleh Streptococcus agalactiae dapat dilakukan dengan vaksinasi. Protein pili Streptococcus agalactiae merupakan kandidat vaksin yang baik. Pili Streptococcus agalactiae berperan penting dalam memfasilitasi ikatan antara Streptococcus agalactiae dengan sel inang. Protein pili Streptococcus agalactiae didapatkan dari proses pemotongan pili. Tikus putih (Rattus novergicus) galur wistar dikelompokkan menjadi 5 kelompok (kontrol dan perlakuan). Satu minggu setelah pemberian protein pili Streptococcus agalactiae terakhir, tikus putih (Rattus novergicus) galur wistar dikorbankan menggunakan teknik dekapitasi. Jaringan tuba falopi diambil dan dilakukan pemeriksaan imunohistokimia. Ekspresi β-defensin-2 hasil imunohistokimia diamati menggunakan mikroskop dengan perbesaran 400x dan dihitung menggunakan software Image-J. Terdapat perbedaan ekspresi β-defensin-2 yang signifikan pada tuba fallopi tikus putih (Rattus novergicus) galur wistar kelompok kontrol dan perlakuan. Semakin tinggi dosis protein pili Streptococcus agalactiae, semakin tinggi pula ekspresi β-defensin-2 pada tuba fallopi tikus putih (Rattus novergicus) galur wistar. Kata kunci: β-defensin-2, Tuba Fallopi, Protein Pili Streptococcus agalactiae
Analysis of Husband Support, Family, Friends dan Health Workers to The Use of MKJP in Women of Reproductive Age Istifadatul Ilmiya; Ika Sulistiyawati
JURNAL KEBIDANAN KESTRA (JKK) Vol. 5 No. 1 (2022): Jurnal Kebidanan Kestra (JKK)
Publisher : Fakultas Kebidanan Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkk.v5i1.1364

Abstract

There are still fewer woman of reproductive age who use long term contraceptive methods compared to those who do not use MKJP. The choice of using MKJP can be influenced by social support, which can provide motivation, change the willingness and ability to solve challenges and provide security for contraceptive acceptors. The purpose of this study was to analyze the support of husbands, family, friends and health workers on the use of MKJP in women of reproductive age. This type of research is an observational analytic study using a cross sectional design. The samples in the study was 225 respondents. The data analysis used logistic regression test. The results showed that there was an effect of support from husbands, friends and health workers on the use of MKJP with p value <0.05 (p value =0.04, p value =0.04, p value =0.03). The conclusion in this study is that social support that can affect the use of MKJP in women of childbearing age is husband support, friend support and health worker support. Suggestions to further researchers are to add various other factors that can influence the selection and determination of the use of MKJP.
Pengaruh Pemberian Protein Pili Streptococcus agalactiae pada Ketebalan Epitel Endometrium Rattus Norvegicus Hening Ryan Aryani; Istifadatul Ilmiya; Nur Rohmah Prihantanti; Dwi Yuni Nur Hidayati; Noorhamdani Noorhamdani
JURNAL KEBIDANAN AKADEMI KEBIDANAN JEMBER Vol 6, No 1 (2022): MARET
Publisher : Akademi Kebidanan Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Infeksi Endometrium merupakan peradangan pada lapisan dalam rahim yang disebabkan karena adanya infeksi yang salah satunya disebabkan oleh Streptococcus agalactiae. Streptococcus agalactiae merupakan bakteri Gram positif yang dapat ditemukan pada saluran genetalia dan gastrointestinal sekitar 30% pada wanita. Akan tetapi bakteri ini mampu beradaptasi sesuai dengan lingkungannya sehingga dapat berubah dari bakteri komensal menjadi pathogen. Penelitian ini merupakan penelitian eksperimental murni yang terdiri dari 25 ekor Rattus norvegicus berjenis kelamin perempuan dan  dibagi menjadi 5 kelompok dimana setiap tikus diberikan perlakuan pada hari ke 0, 7 dan 14. Pengambilan data dilakukan menggunakan software image raster 3 dan pengumpulan data kemudian di analisis menggunakan One Way Anova. Hasil penelitian menunjukkan rerata ketebalan epitel endometrium pada kelompok kontrol positif memiliki rerata terendah yaitu 17,89μm, sedangkan rerata ketebalan epitel endometrium tertinggi terdapat pada kelompok perlakuan ketiga yaitu 32,86 μm. Sedangkan hasil tes One Way Anova menunjukkan p=0,000 (p-value<0,05), yang membuktikan bahwa terdapat perbedaan peningkatan yang bermakna terhadap ketebalan epitel endometrium antara Rattus norvegicus pada masing-masing kelompok perlakuan. Maka dapat disimpulkan bahwa pemberian protein pili Streptococcus agalactiae terbukti meningkatkan ketebalan epitel endometrium Rattus norvegicus
PERAN PENDIDIKAN GIZI DALAM MENINGKATKAN PENGETAHUAN DAN SIKAP SISWA SMA TENTANG GIZI SEIMBANG Aini, Nurul; Ilmiya, Istifadatul
Majalah Ilmiah "PELITA ILMU" Vol 7 No 2 (2024): PELITA ILMU (DESEMBER 2024)
Publisher : STIA Pembangunan Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37849/mipi.v7i2.423

Abstract

Kegiatan pengabdian kepada masyarakat ini dilaksanakan di Sekolah Menengah Atas (SMA) dengan sasaran para siswa di SMAN 02 Tanggul dan SMK Farmasi Jember. Berdasarkan hasil survey awal ditemukan 12,2% belum memperhatikan kebersihan bungkus atau wadah makanan dan minuman, 20,2% belum memahami pentingnya sarapan pagi dan 17,5% belum mengkonsumsi gizi seimbang. Hasil wawancara menunjukkan siswa sering mengkonsumsi minuman dingin manis daripada air putih, selain itu siswa lebih memilih untuk mengkonsumsi junk food dan fast food dari pada makanan yang mengandung gizi seimbang. Tujuan kegiatan adalah guna meningkatkan pengetahuan, dan sikap siswa dalam mengkonsumsi gizi seimbang melalui pendidikan gizi. Pelaksanaan kegiatan dilaksanakan selama bulan Mei 2024. Metode kegiatan yang dilaksanakan yaitu pendidikan gizi kepada remaja tentang gizi seimbang, kuantitas dan kualitas konsumsi makanan, kebutuhan gizi remaja, masalah gizi pada remaja serta dampaknya pada kesehatan reproduksi. Hasil evaluasi kegiatan menunjukkan terjadi peningkatan pengetahuan dan kesadaran siswa akan pentingnya konsumsi makanan seimbang serta pengaruhnya terhadap kesehatan reproduksi .
The Effect of Using Contraceptives on The Nutritional Status of Woman of Childbearing Age Ilmiya, Istifadatul
JURNAL KEBIDANAN KESTRA (JKK) Vol. 7 No. 2 (2025): Jurnal Kebidanan Kestra (JKK)
Publisher : Fakultas Kebidanan Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkk.v7i2.2463

Abstract

Nutritional status during this period, especially in women of childbearing age, is influenced by several things, including the use of contraceptives. Side effects of using contraception include excess weight gain which can cause various diseases. Meanwhile, long-term impacts for families who do not use contraception can be in the form of increasing population, food and nutrition shortages, low education, lack of job opportunities, high birth and death rates. The aim of this study was to analyze the effect of contraceptive use on nutritional status in women of childbearing age. This research is an analytical observational study with a cross sectional design. The research sample consisted of 225 respondents using Eta Squared test data analysis. The results of the study show that contraceptive use has a positive and significant effect on nutritional status (p = 0.24), which means that the hypothesis is accepted if F count > F table (p = 0.05) at a certain probability. Suggestions for future researchers are to pay attention to other factors so that the nutritional status of women of childbearing age remains normal even though they use contraception
Pemberdayaan Kader Posyandu dalam Pemilihan Kontrasepsi yang sesuai dengan Status Gizi Ilmiya, Istifadatul
Dental Agromedis Vol. 3 No. 1 (2025): Mei
Publisher : Fakultas Kedokteran Gigi, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/da.v3i1.1624

Abstract

Lack of community participation in family planning programs with the use of contraception can cause health problems for mothers and children, and affect social conditions and the level of family welfare. Empowerment of cadres in promotion and counseling about various methods of family planning and being able to determine nutritional status is considered important for the success of the family planning program. The purpose of this service is to increase the knowledge and skills of cadres related to contraceptives and determine the nutritional status of women of childbearing age. The results of the service showed that there was a significant increase in cadre knowledge after education related to various contraceptives was carried out and there was an increase in ability related to determining nutritional status in women of childbearing age. The conclusion of community service activities in this case is that education and simulation methods can increase cadre knowledge regarding contraception and cadre skills in determining nutritional status in women of childbearing age.Keywords: Cadre empowerment, Contraception, Nutritional Status
Pemberdayaan Peran Kader Dalam Pencegahan Stunting Dengan Penyuluhan Gizi Di Desa Menampu Ilmiya, Istifadatul; Aini, Nurul; Putri Wayanshakty, Januar
Jurnal Empathy Pengabdian Kepada Masyarakat Jurnal Empathy Pengabdian Kepada Masyarakat Volume 6 Nomor 1 Tahun 2025
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jurnalempathy.v6i1.331

Abstract

Background: Stunting is a condition of growth failure in children that can be caused by chronic malnutrition so that children are too short for their age, which is at risk of increased morbidity and mortality, decreased immune system and increased risk of infection. The prevalence of stunting in Indonesia in 2023 is 15.8%, in East Java 13.8% and in Jember 29.7%. This community service activity aims to improve the ability of cadres as educators in reducing the incidence of stunting in organizing posyandu activities. Methods: The activities were carried out in Menampu Village in December 2024 targeting the posyandu cadres. This included the distribution of questionnaires, education on stunting, and practice in determining nutritional status. An evaluation was conducted to assess the improvement in the knowledge and skills of the cadres. Results: The results of the activity showed an increase in cadre knowledge related to stunting, most of which were in the good category (73.33%) and there was an increase in cadre skills in the correct category (100%) in determining nutritional status. Conclusion: Knowledge about stunting and skills to determine nutritional status improved after the counseling and training sessions. It is recommended to have periodic follow-ups and to expand the program to other villages for the prevention of stunting.