Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya Gema Kesehatan
Erawati
Institut Ilmu Kesehatan Bhakti Wiyata Kediri
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
KORELASI HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) DENGAN MONOSIT PADA PASIEN TUBERKULOSIS SETELAH PENGOBATAN: CORRELATION BETWEEN HIGH-SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) AND MONOCYTES IN TUBERCULOSIS PATIENTS AFTER TREATMENT Frieti Vega Nela; Erawati; Triffit Imasari; Erlina Setia Ningrum
GEMA KESEHATAN Vol. 17 No. 1 (2025): Juni 2025
Publisher : POLTEKKES KEMENKES JAYAPURA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47539/gk.v17i1.488

Abstract

Tuberkulosis (TBC) merupakan penyakit infeksius yang berlangsung lama dan utamanya mempengaruhi organ paru. Kondisi ini disebabkan oleh bakteri Mycobacterium tuberculosis, yang biasanya menyerang sistem pernapasan manusia. Pemeriksaan High Sensitivity C-Reactive Protein (hs-CRP) dan monosit dapat digunakan sebagai pemeriksaan untuk mengetahui terjadinya inflamasi pasien tuberkulosis. Tujuan penelitian ini untuk mengetahui hubungan hs-CRP dengan monosit pada pasien tuberkulosis setelah pengobatan. Desain penelitian yang digunakan adalah cross sectional dengan teknik pengambilan sampel menggunakan metode accidental sampling dengan jumlah sampel sebanyak 15 sampel. Hasil pemeriksaan hs-CRP didapatkan nilai rata-rata 3,22 mg/L dan rata-rata monosit pada pasien tuberkulosis setelah pengobatan yaitu 540,80 mm3. Analisa data dilakukan dengan menggunakan uji normalitas Shapiro-wilk dan uji korelasi menggunakan uji pearson product moment. Berdasarkan uji pearson product moment didapatkan nilai signifikasi 0,037 dengan nilai koefisien korelasi yang diperoleh yaitu 0,542. Kesimpulan dari penelitian ini menunjukkan adanya korelasi antara hs-CRP dengan monosit pada pasien tuberkulosis setelah pengobatan, dengan korelasi positif yang menandakan korelasi kuat antara hasil hs-CRP dengan monosit pada pasien tuberkulosis setelah pengobatan. Kata kunci: hs-CRP, Monosit, Tuberkulosis   Tuberculosis (TB) is a chronic infectious disease that primarily affects the lungs and is caused by Mycobacterium tuberculosis. This pathogen typically targets the human respiratory system. High-sensitivity C-reactive protein (hs-CRP) and monocyte levels can serve as diagnostic indicators to assess inflammation in TB patients. This study examines the relationship between hs-CRP and monocyte levels in tuberculosis patients following treatment. A cross-sectional study design with accidental sampling was employed, involving 15 participants. The mean hs-CRP level was 3.22 mg/L, while the mean monocyte count was 540.80 cells/mm³. Data were analyzed using the Shapiro-Wilk normality test and Pearson product-moment correlation test. The Pearson test yielded a significance value of 0.037 and a correlation coefficient (r) of 0.542. The results indicate a statistically significant positive correlation between hs-CRP and monocyte levels in tuberculosis patients after treatment. This suggests a moderate to strong association between inflammatory response and monocyte activity post-therapy. Keywords : hs-CRP, Monocytes, Tuberculosis
Identification of Gram-Negative Bacteriuria among Diabetes Mellitus Patients at X Public Health Center, Kediri TRIFFIT IMASARI; Erawati; Siska Kusuma Wardani; Indra Fauzi Sabban; Vanda Pitasari
Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya Vol 7 No 1 (2026): Juni 2026
Publisher : Fakultas Sains, Teknologi, dan Analsisi Institut ilmu Kesehatan Bhakti Wiyata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56399/jst.v7i1.400

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by a steadily increasing prevalence both globally and nationally. Patients with DM are highly susceptible to various infections, with Urinary Tract Infection (UTI) being one of the most frequent complications. The hyperglycemic state in DM patients leads to glycosuria, a condition where the presence of glucose in the urine creates an ideal environment for the proliferation of pathogenic microorganisms. Microbiologically, Gram-negative bacteria are the primary etiology of UTIs in diabetic patients. Bacteria such as Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis possess specific virulence factors that facilitate adherence to the urinary tract epithelium. The objective of this research was to identify Gram-negative bacteria and determine their percentage distribution among Diabetes Mellitus patients at Public Health Center X in Kediri. This research employed a descriptive research method with an accidental sampling technique, utilizing 14 urine specimens from DM patients. The results revealed the presence of Klebsiella sp. (36%), Escherichia coli (50%), and Salmonella sp. (14%) in the urine of the subjects. Based on these findings, it can be concluded that urinary tract infections in Diabetes Mellitus patients at Public Health Center X, Kediri, are caused by several types of pathogenic bacteria, with the highest prevalence being Escherichia coli, followed by Klebsiella sp., Salmonella sp., and Proteus sp. Early detection and management of bacterial infections are essential to prevent further complications in patients with Diabetes Mellitus
Co-Authors Erlina Setia Ningrum Frieti Vega Nela Indra Fauzi Sabban Siska Kusuma Wardani, Siska Kusuma Triffit Imasari Vanda Pitasari