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All Journal Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research)
Andini, Nurul Sulfi
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Agriculture, Biological Sciences & Forestry Veterinary

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Effect of Noise Stress Exposusre on Heart Histopathology of White Rat (Rattus Norvegicus) Rarasmika, Ainun; Andini, Nurul Sulfi; Fatmawati, Dian; Musdalifah; Sari, Dwi Kesuma; Purba, Fika Yuliza
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 8 No. 1, JANUARY 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v8i1.28495

Abstract

Noise is one of stressors that can occur over a long period and adversely affect health if it exceeds the ability to adapt. The heart plays a significant role and is the main organ in distributing oxygen, substances, minerals, and other organic substances in the blood. The samples used in this study amounted to 24 white male rats divided into four groups. Group K1 is a control rat that does not give treatment, Group P1 is given noise treatment for 6 hours of exposure, Group P2 with 9 hours of exposure, and Group P3 with a dose of 12 hours of exposure. Heart samples were collected and histology preparations were obtain by Hematoxylin-Eosin (HE) staining, and microscopic observe were made with 10μm and 40μm magnification. The results of the study were then adjusted to degree of damage and analyzed using the Kruskall-Wallis test and the Mann-Whitney test to showing changes in the form of necrosis and inflammation due to noise stress with different levels of damage and obtained a value below the critical value (p<0.05). The degree of damage that occurs is in line with the length of noise exposure given. Severe damage occurred in Group 3 with noise exposer of 12 hours/day for 29 days.
The EFFECTIVENESS OF MANGO LEAF EXTRACT SUPPLEMENTATION (MANGIFERA INDICA L.) ON METABOLIC DISEASE PANEL OF WISTAR RATS (RATTUS NORVEGICUS) INDUCED BY HIGH-FAT DIET: Diabetes, Glucosa, Mango Leaf, Supplement Gilang, Gilang Ramadhan; Ramadhan K., Muhammad Zoel Vitra; Azzuhdi, Faiz Adlan; Azzahra, Nabila; Nurlina; Zahrani, Putri Dyah; Amriani, Rini; Sari, Dwi Kesuma; Bahmid, Nur Alif; Andini, Nurul Sulfi
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 10, No 1, JANUARY 2026
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v10i1.48703

Abstract

High-calorie foods can cause obesity if consumed in excess. Obesity occurs due to excessive fat accumulation in the body. Excess weight is a major risk factor for secondary disorders in pets, such as diabetes mellitus. Diabetes mellitus occurs due to high blood glucose levels. Mango leaf extract contains bioactive compounds that can lower and normalise blood glucose levels and can be used as a supplement. This study aims to determine the effectiveness of mango leaf extract supplementation induced by a high-fat diet on blood glucose levels. This study used arumanis and golek mango leaf. The methods used were extraction and in vivo testing. Extraction was performed on mango leaf, and the extraction results were administered to test animals in vivo. The phytochemical results showed that arumanis and golek mango leaf contain flavonoids, tannins, alkaloids, and saponins. The results showed that arumanis mango leaf extract was more effective in lowering blood glucose levels than golek mango leaf extract. These findings are expected to contribute to the development of knowledge about supplements and drug substitutes, as well as to identify more practical methods for drug therapy for diabetes mellitus in pets.
Co-Authors Amriani, Rini Azzahra, Nabila Azzuhdi, Faiz Adlan Bahmid, Nur Alif Dwi Kesuma Sari Fatmawati, Dian Gilang, Gilang Ramadhan Musdalifah Nurlina Purba, Fika Yuliza Ramadhan K., Muhammad Zoel Vitra Rarasmika, Ainun Zahrani, Putri Dyah