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Hubungan Kadar HbA1c dan Usia dengan Kejadian Neuropati Diabetik pada Pasien Diabetes Melitus Fikri, Elfin Ainul; Sulistyani, Sulistyani; Setiawan, Iwan; Puspitasari, Metana
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 14 No 3 (2024): Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal: Juli 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/pskm.v14i3.1986

Abstract

Neuropati diabetik adalah rusaknya sistem saraf tepi yang disebabkan oleh pembuluh darah mikro yang rusak sehingga darah tidak bisa mengalir ke jaringan saraf. International Diabetes Federation memperkirakan 463ijuta orang dimseluruh dunia menderitaidiabetes melitus per tahun 2019. Kejadian diabetesnmelitus di Indonesia menempati peringkat ketujuh dunia dengan 10,7 juta kasus. Prevalensi neuropatimdiabetik padanpasien diabetesnmelitus mencapai 40,3%. Kejadian neuropati diabetik meningkatnseiring bertambahnyanusia pasienidiabetes melitus. Kejadian neuropati dapat diprediksi melalui kontrol glikemik yang ketat dengan memantau kadar HbA1c. Penelitian ini bertujuan untuk mengetahuinhubungan antara usia dannkadar HbA1c dengan kejadiannneuropati diabetiknpada pasien diabetes melitus. Penelitian ini menggunakan desain penelitian analitik observasional dengan pendekatan cross-sectional. Sampelnpada penelitiannini merupakan semua penderita diabetes melitus yang memiliki kriteria sesusai dengan yang diperlukan peneliti dengan jumlah sebanyak 65 sampel yang dipilih dengan menggunakan pendekatan total sampling. Neuropati diabetikndiukur dengan menggunakan tes monofilamen. Berdasarkan uji Chi-Square, hasil antara kadar Hb1Ac dengan neuropati diabetik pasien diabetes melitus didapatkan p-value =0,000. Sedangkan uji Chi-Square antara usia dengan neuropati diabetik pasien diabetes melitus didapatkan p-value =0,000. Terdapat hubungan yang signifikannantara HbA1c dan usia dengannkejadian neuropati diabetik pada pasien diabetesnmelitus di Puskesmas Gatak, Kabupaten Sukoharjo.
PENINGKATAN PEMAHAMAN PEMERIKSAAN RUTIN TEKANAN DARAH DALAM UPAYA PENCEGAHAN HIPERTENSI: PENYULUHAN KESEHATAN Puspitasari, Metana; Yamsun, Rahmat Dani; Kencana, Nabila Safhira Titan
Jurnal Pengabdian Masyarakat Medika Vol 4. No. 2, September 2024
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v4i2.2806

Abstract

ABSTRAK Hipertensi adalah salah satu penyakit tidak menular (PTM) yang membutuhkan perhatian karena jumlahnya meningkat setiap tahunnya. Hipertensi terjadi ketika tekanan darah sistolik naik ke 140 mmHg atau lebih, dan/atau tekanan darah diastolik mencapai 90 mmHg atau lebih. Data menunjukkan bahwa angka prevalensi hipertensi mengalami kenaikan 25,8% pada tahun 2013 menjadi 34,1% pada tahun 2018, hanya 30% dari kasus hipertensi yang terdeteksi sehingga menyebabkan keterlambatan pengobatan yang akan menimbulkan komplikasi. Untuk menangani kasus hipertensi, diperlukan pendekatan yang komprehensif dan holistik yang mencakup langkah-langkah promotif, preventif, kuratif, dan rehabilitatif. Tujuan kegiatan pengabdian masyarakat ini menambah edukasi pada masyarakat mengenai penyakit tidak menular khususnya hipertensi sebagai upaya promotif dan preventif dari penyakit hipertensi. Penelitian ini menerapkan pendekatan desain one group pre-test post-test. Sejumlah 34 peserta yang berpartisipasi berasal dari komunitas di Kelurahan Triyagan, Kecamatan Mojolaban, Kabupaten Sukoharjo. Data dianalisis dengan menggunakan Wilcoxon test. Hasil penelitian menunjukkan bahwa skor rata-rata pada tahap pretest adalah 78,53%, sementara skor rata-rata pada tahap posttest adalah 87,06%. Hasil analisis mengindikasikan bahwa penyuluhan Kesehatan telah mempengaruhi pengetahuan masyarakat tentang hipertensi, hal ini dapat disimpulkan karena nilai p < 0,05.   ABSTRACT Hypertension, a non-communicable disease (NCD), warrants attention due to its increasing prevalence year by year. It is characterized by systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Data reveals a rise in hypertension prevalence from 25.8% in 2013 to 34.1% in 2018, with only 30% of cases being detected, resulting in treatment delays and potential complications. To combat hypertension, a comprehensive approach encompassing promotive, preventive, curative, and rehabilitative measures is essential. This community service initiative aims to educate the public, particularly about non-communicable diseases like hypertension, for promotive and preventive purposes. The study employs a one-group pre-test post-test design, involving 34 participants from Triyagan, Mojolaban, Sukoharjo Regency. Data analysis utilizes the Wilcoxon test. Findings indicate that the average pretest score was 78.53%, while the posttest score averaged at 87.06%. The analysis confirms that health education significantly influences public knowledge of hypertension, as evidenced by a p-value <0.05.
Correlation between Total Monocyte, Lymphocyte and Basophil Counts, as well as Monocyte-Lymphocyte Ratio with Hematocrit as Indicators of Plasma Leakage in Dengue Virus Infection Jamiko, Safari Wahyu; Yulistina, Desita; Ardhana, Regita; Puspitasari, Metana
Biomedika Vol 16, No 2 (2024): Biomedika Agustus 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Severe dengue virus (DVI) infection is characterized by plasma leakage (PL) due to the release of vasoactive cytokines by immunocytes such as monocytes, lymphocytes, and basophils. The response to Dengue Virus (DENV) also affects the kinetics of monocytes, lymphocytes, and basophils, thus changing the examination results of leukocyte types and monocyte-lymphocyte ratio (MLR). MLR has been used as a biomarker and outcome predictor in various diseases but not to predict PL in DVI. Objectives: To see the correlation of monocytes, lymphocytes, basophils, and MLR with hematocrit (Hct) which is a PL indicator. Methods: Correlative analytical research with a cross-sectional approach was conducted on 71 pediatric DVI patients at PKU Muhammadiyah Sampangan Hospital, Surakarta, in February- April 2024. The diagnosis of DVI was confirmed by a pediatrician according to WHO 2009 criteria. DVI patients who had a history of allergies, worms, malignancies, and DVI with secondary infections were excluded from the study. Absolute monocyte (AMC), lymphocyte (ALC), and basophil (ABC) count values ​​, as well as MLR and Hct, were obtained from the results of a complete blood examination using a hematology analyzer. The Spearman Rho’s correlation test was used to determine the relationship between variables with values ​​of p<0.05 and r>0.4 considered significant. Results: research obtained AMC=median 313 (IQR 192) mm-3, ALC= median 1225 (IQR 1039) mm-3, ABC=0 mm-3, MLR=0.22 (0.23). The results of the correlation analysis of AMC, ALC, and MLR with Hct are AMC (r=0.01, p=0.918), ALC (r=0.351, p=0.003), and MLR (r=0.41, p<0.001), while the correlation between ABC and Hct could not be done due to no data variation. Conclusion: There is a significant correlation between MLR and Hct, but not with AMC, ALC, and ABC and Hct. MLR can potentially predict plasma leakage in patients with dengue virus infection.
Correlation of Eosinophil-basophil Count and Ratio with Length of Stay in Children Dengue Infection Yunitama, Alifa Agil Dhillu; Puspitasari, Metana; Jatmiko, Safari Wahyu; Fauziyah, Nida Faradisa
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5486

Abstract

Purpose: This study purpose is to determine the correlation between the number of absolute eosinophils, absolute basophils, and eosinophil-basophil ratio (EBR) with the length of stay of pediatric patients with dengue virus infection. Methodology: The study design used cross-sectional. The samples used in this study were taken from routine hematologic laboratory medical record data for the period January-October 2024, using consecutive non-probability sampling technique. Results: 49 samples were obtained and met the restriction criteria as subjects of this study. The results of the Spearman correlation bivariate test showed that the number of absolute eosinophil count, absolute basophil count, and EBR with length of stay had statistical data results respectively p = 0.139, p = 0.993, and p = 0.536. Applications/Originality/Value: This study provides a reference in laboratory results to determine the length of stay (LOS) in children with dengue virus infection.
Correlation of Dengue Infection Severity with Abdominal Pain, Delta Hematocrit, Platelet Count, and Delta Hematocrit-Platelet Ratio in Pediatric Patients Agustina, Dinda Dwi; Puspitasari, Metana; Jatmiko, Safari Wahyu
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5503

Abstract

Purpose: This study aimed to determine the correlation between the severity of dengue infection and abdominal pain, delta hematocrit, platelet levels, and the delta hematocrit-platelet ratio. Methodology: the study used a correlational observational design with a cross-sectional approach. Data were obtained from the medical records of dengue infection patients at PKU Muhammadiyah Sampangan Hospital from October–November 2024. A total of 39 samples were selected using a consecutive non-probability sampling technique. Data analysis was performed using JASP statistical software version 0.19.1.0. Results: The study revealed no significant relationship between the severity of dengue infection and abdominal pain (p=0.089), delta hematocrit (p=0.589), platelet levels (p=0.068), or the delta hematocrit-platelet ratio (p=0.740). Applications/Originality/Value: This study provides valuable insights into the limitations of individual clinical and laboratory parameters, emphasizing the need for a comprehensive approach to assessing dengue severity in pediatric patients.
Correlation of Platelet Count, PDW, and MPV with Length of Stay in Children with Dengue Infection Faqihudin, Fadli Rizal; Puspitasari, Metana; Jatmitko, Safari Wahtu; Dewi, Listiana Masyita
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5510

Abstract

Purpose: The research aim to determine and analyze the correlation between platelet count, platelet distribution width, mean platelet volume and length of stay in children dengue virus patients. Methodology: This research used correlative observational study employed a cross-sectional design and included 48 children patients with dengue virus infection treated at PKU Muhammadiyah Sampangan Hospital, Surakarta. Platelet count, PDW, MPV, and LoS data were obtained from medical records. Statistical analysis to evaluate the correlation between these variables. Results: Results The study found platelet count (r = 0.28, p = 0.849), PDW (r = -0.110, p = 0.456), or MPV (r = 0.105, p = 0.477) no significant correlation with the length of stay. The result suggest that these platelet count, PDW, MPV are not acurate predictors of LoS in children dengue patients. Applications/Originality/Value: The platelet count, PDW, MPV are not reliable predictors the length of stay in children with dengue virus infection. This finding suggests for future studies, emphazie the need for a comprehensive clinical assessment rather than relying solely on platelet parameters when managing children dengue patients to predictors the length of stay in children with dengue virus infection and inform doctors in monitoring the course of dengue infection so that it is expected to reduce the incidence dengue infection in children.
Correlation of Mean Corpuscular Hemoglobin, Mean Corpuscular Hemoglobin Concentration and Platelet to Hemoglobin Ratio with the Degree of Dengue Virus Infection in Pediatric Patients Alim, Fika Nurul; Jatmiko, Safari Wahyu; Puspitasari, Metana
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5511

Abstract

Purpose: This study aimed to evaluate the correlation between MCH, MCHC, and PHR with the severity of DVI in pediatric patients. Methodology: A cross-sectional observational study was conducted on 47 pediatric DVI patients at PKU Muhammadiyah Sampangan Hospital, Surakarta. Medical records from January to May 2024 were analyzed. Data were statistically evaluated using Spearman’s test to determine the correlation between variables. Results: Among 47 patients, 57.45% had dengue without warning signs, while 42.55% had dengue with warning signs, with no cases of severe dengue. There was no significant correlation between MCH (p=0.383, r=0.130), MCHC (p=0.457, r=-0.111), or PHR (p=0.064, r=-0.273) and the severity of DVI. Applications/Originality/Value: This study examines the roles of MCH, MCHC, and PHR in pediatric dengue virus infection, finding no significant correlation with disease severity. It provides a basis for future research on alternative hematological markers to enhance clinical assessment. This research introduces PHR as a novel parameter in dengue studies, providing a unique perspective on its potential relevance to disease pathophysiology.
Relationship between Neutrophil to Lymphocyte Ratio (NLR) and Lymphocyte to Monocyte Ratio (LMR) with Severity of Ischemic Stroke Paramadina, Izzati; Kusumaningsih, Dwi; Sulistyani, S; Puspitasari, Metana
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5516

Abstract

Purpose: The purpose of this study was to determine the correlation between Neutrophil to Lymphocyte Ratio (NLR) and Lymphocyte to Monocyte Ratio (LMR) with the severity of ischemic stroke. Methodology: According to the criteria, a cross-sectional sample of ischemic stroke patients at Yarsis Islamic Hospital in Surakarta (January 2023–November 2024) participated in this observational analytical study, which used the National Institutes of Health Stroke Scale (NIHSS) as a severity measure. Results: 44 subjects were obtained with an equal ratio of gender and hypertension was the most common comorbidity. A substantial relationship between the NLR with the NIHSS score (p value = 0.001) and between LMR with the NIHSS score (p value < 0.001) was discovered using bivariate analysis. NLR (OR 4.713; p = 0.044) and LMR (OR 10.780; p = 0.043) had a 42.2% (R square = 0.422) impact on the severity of ischemic stroke, according to the findings of the logistic regression test. Applications: Based on this study, there is a significant relationship between NLR and LMR with the severity of ischemic stroke. As a consequence, NLR and LMR test findings may serve as a substitute indicator of acute ischemic stroke patients' severity.
The Relation between Fasting Blood Glucose and Triglyceride with GFR in Type 2 DM Patients Hartia, Nabila Putri; Puspitasari, Metana; Sintowati, Retno; Fithriyah, Saidatul
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5523

Abstract

Purpose: Identify the relation between FBG and triglyceride with GFR in T2DM patients. Methodology: This observational quantitative research used a cross-sectional design. Data were obtained from the medical records of 50 Prolanis T2DM patients in 2023 at the Puskesmas Karangnongko, Klaten Regency, using consecutive sampling technique. The bivariate analysis used was the Spearman test. Results: Spearman test results show that there is no significant relation between FBG with GFR in type 2 diabetes mellitus patients (p-value=0.695; r-value=0.057). Apart from that, there is also no relation between triglycerides with GFR in type 2 diabetes mellitus patients (p-value=0.654; r-value=-0.065). Applications/Originality/Value: This research provides information regarding considerations for FBG and triglycerides as important components for detecting a decrease in GFR which can be an indicator of diabetic nephropathy.
Correlation of Length of Fever before Hospital Admission, Hematocrit, Platelet Count, and Leukocytes with Length of Hospitalization Dengue Virus Infection Patients in Children Pambudi, Nasrurrofiq Risvana Bayu; Puspitasari, Metana; Jatmiko, Safari Wahyu; Aisyah, Riandini; Alfajri, Asri
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5525

Abstract

Purpose: To analyze the relationship between fever duration before admission, hematocrit, platelet count, and leukocyte count with length of hospital stay in pediatric patients with dengue infection. Methodology: This observational study with cross-sectional design was conducted at PKU Muhammadiyah Sampangan Hospital, Surakarta, using secondary data from medical records. Forty pediatric patients were selected through consecutive non-probability sampling technique. Statistical analysis was performed with Spearman correlation test using statistical applications. Results: There was a significant association between fever duration before admission and length of hospitalization (r = -0.407, p = 0.009). However, there was no significant association between hematocrit (r = 0.136, p = 0.403), platelet count (r = 0.101, p = 0.536), or leukocyte count (r = 0.111, p = 0.496) with length of hospitalization. Applications/Originality/Value: This study highlights the importance of early detection and intervention in managing pediatric dengue cases. The significant correlation found between fever duration prior to admission and length of stay underscores the need for prompt treatment to minimize hospital stay due to associated inflammation in the body. In contrast, the lack of significant associations between hematocrit, platelet count, leukocyte level and duration of hospitalization highlights the complexity of factors influencing outcomes and the need to explore other prognostic markers. This study conducted in an endemic region of Indonesia contributes to understanding the management of dengue virus infection and underscores the importance of a comprehensive multifactorial approach to improve patient care strategies.