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All Journal The New Ropanasuri Journal of Surgery Eduvest - Journal of Universal Studies
Putra, M. Arza
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Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Neuroscience Social Sciences

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Risk Factors in Descending Necrotizing Mediastinitis Following Submandibular Abscess at dr. Cipto Mangunkusumo Hospital in January 2012 – July 2016 Putra, Muhammad Arza; Pratama, Raditya; Kekalih, Aria
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Abstract

Introduction. Descending necrotizing mediastinitis (DNM) encountered problem of a high mortality rate. The increasing number of incidence and the need of immediate intervention DNM cases urge surgeons to manage early preventions and adequate therapy. The purpose of thisstudy is to find risk factors that correlate to the incidence of DNM in submandibular abscess patients. Method. Cross sectional study conducted enrolling all patients diagnosed with submandibular abscess that developed to DNM and treated surgically in emergency operating theater in period of January 2012 to July 2016 were reviewed. Mediastinitis which was not following submandibular abscess, those were not treated surgically or treated by other than the division of thoracic and cardiovascularsurgery, and those of pediatrics were not included on the study. The incidence of DNM was the dependent variable on the study; risk factors such as gender, age, body mass index (BMI), comorbid(s), leukocyte counts, and microorganism(s) were independent variables on the study. Results. There were 68 subjects enrolled on the study. The met the inclusion and exclusion criteria. Subjects characteristics are shown in table 1. Septic condition, surgical intervention, postoperative complications, and mortality are shown in table 2. There was no correlation between gender (p = 0.656), age (p = 0.763), comorbid(s) (p = 0.767 and 0.952). It also found that leukocyte counts, and cultured microorganism(s) showed no significant correlation. Conclusion. Not a single risk factor specifically correlatesto the incidence of DNM in subjects with submandibular abscess. Thus, so those with submandibular abscess have a same risk to have DNM developed.
Pattern of Prophylactic Antibiotic Prescribing in Surgical Patients at the University of Indonesia Hospital Wardani, Tita Kusuma; Andrajati, Retnosari; Putra, M. Arza; Dwiputra, Anggara Gilang
Eduvest - Journal of Universal Studies Vol. 5 No. 5 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i5.51105

Abstract

Surgical procedures involve interventions that may compromise tissue integrity, necessitating prophylactic antibiotics to prevent surgical site infections (SSIs). Proper timing, selection, and administration of antibiotics are crucial to achieving optimal therapeutic outcomes. This study aimed to evaluate the prescribing patterns of prophylactic antibiotics in patients undergoing surgical procedures at the University of Indonesia Hospital and assess adherence to established guidelines. A retrospective observational study analyzed medical records of patients who underwent surgery. Data collected included the type of antibiotics prescribed, timing of administration, dosage, duration, and adherence to national and international guidelines. Descriptive statistics were used to summarize the findings. The study analyzed 213 surgical patients at the University of Indonesia Hospital in September 2024. Prophylactic antibiotics were prescribed in 90.61% of cases, predominantly Cefazolin (86.48%), with doses of 2 g (76.12%) and 1 g (10.36%). Most patients (97.93%) received antibiotics 30–60 minutes pre-incision. All antibiotics were administered intravenously with research results, 4.29% were affected by IDO. These findings highlight overall adherence to prophylactic antibiotic guidelines, with minor deviations in timing and dosage observed in a few cases. Optimal prescribing practices were achieved in most surgical patients to reduce the risk of SSI.
Co-Authors Aria Kekalih Dwiputra, Anggara Gilang Raditya Pratama Retnosari Andrajati Wardani, Tita Kusuma