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All Journal International Journal of Integrated Health Sciences Sari Pediatri Indonesian Journal of Cancer Cermin Dunia Kedokteran
Mustika, Putu Pradnyanita
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Analisis Faktor Faktor Risiko Anemia pada Anak di Rumah Sakit Umum Daerah Wangaya Bali Suriadi, Regina; Mustika, Putu Pradnyanita; Wielim, Edbert; Cynthia, Cynthia; Suryawan, I Wayan Bikin
Sari Pediatri Vol 27, No 1 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.1.2025.32-7

Abstract

Latar belakang. Anemia merupakan kondisi yang sering ditemukan pada anak. Anemia memiliki dampak yang besar bagi pertumbuhan, perkembangan, morbiditas dan mortalitas anak, sehingga penting untuk mencegah dan menangani anemia pada anak sejak dini. Tujuan. Penelitian ini bertujuan mengetahui hubungan kejadian anemia dan faktor-faktor determinannya pada pasien anak.Metode. Penelitian ini adalah penelitian cross-sectional analitik melibatkan pada pasien anak dengan anemia yang datang ke Rumah Sakit Umum Daerah Wangaya, Bali selama periode Januari 2023 hingga jumlah sampel terpenuhi. Berdasarkan jumlah sampel minimal untuk penelitian cross-sectional dibutuhkan minimal 76 sampel. Kriteria inklusi adalah pasien anak berusia 1 bulan -18 tahun yang terdiagnosis anemia. Pasien dengan catatan medis yang tidak lengkap dikeluarkan dari penelitianHasil. Sebanyak 76 pasien anak dengan anemia diikutsertakan dalam penelitian ini. Rata-rata kadar Hb 12-20% lebih rendah pada kelompok dengan berat badan lahir rendah, usia ibu, lama pemberian ASI, stunted, gizi kurang, dan riwayat gastroenteritis, hasil ini juga bermakna secara statistik. Analisis multivariat menunjukkan faktor yang memiliki hubungan paling kuat terhadap kadar Hb anak adalah gizi kurang (koefisien ?: 0,283).Kesimpulan. Terdapat hubungan antara faktor anak (BBLR, stunted, gizi kurang, riwayat gastroenteritis) dan faktor ibu (usia ibu, lama pemberian ASI) terhadap kejadian anemia pada anak.
Acute Myeloid Leukemia in a Three-Year-Old Girl Mimicking Chronic Myeloid Leukemia in Blast Crisis, Challenge in Diagnosis and Treatment in Limited-Resourced Health Care Facility: A Case Report Predani, Ni Luh Putu Diaswari; Gunawan, Andre; Mustika, Putu Pradnyanita; Tedja, I Gusti Ayu Wiradari
Indonesian Journal of Cancer Vol 18, No 1 (2024): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i1.1073

Abstract

Introduction: : Acute myeloid leukemia (AML) is the second most common hematologic cancer in childhood. Clinically, AML has similar symptoms to other types of leukemias, and diagnosis remains a challenge due to limited access to pediatric hemato-oncology diagnostic examination. This study aims to report AML in a 3-year-old girl who was first suspected of Chronic Myeloid Leukemia (CML) in blast crisis, using a combination of clinical-hematology parameters and conventional morphology examination in a limited-resourced healthcare facility. Case Presentation: A 3-year-old girl was referred from a rural Eastern Indonesia hospital with symptoms of prolonged fever, leucocytosis, severe anemia, and severe thrombocytopenia. In the previous hospital, the patient had a history of hyperleukocytosis and peripheral blood smear suspected of CML in blast crisis. A peripheral blood smear was repeated in our hospital and showed findings of Auer rod cells suggesting AML. Two bags of packed red cells and 2 thrombocyte concentrations were administered before referral for further diagnostic evaluation with bone marrow aspiration. Bone marrow aspiration revealed multiple nucleoli suggested for AML with FAB classification as M4 subtypes, and she received chemotherapy in a tertiary hospitalConclusions: With limited resources, suspicion based on persistent clinical symptoms, routine hematology tests, and peripheral blood smear examination are important to distinguish AML from CML in blast crisis. Understanding clinical hematology parameters and peripheral blood smears is the first step in AML diagnosis pathway and decision for further diagnostic referral. Supportive therapy and early recognition of oncologic emergency must be done before referral to a tertiary referral hospital.
Tanda-tanda Klinis Demam Rematik - Serial Kasus Liman, Claudia Natasha; Gozali, Ferry; Mustika, Putu Pradnyanita
Cermin Dunia Kedokteran Vol 51 No 9 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i9.1062

Abstract

Acute rheumatic fever is an autoimmune disease following group A β-hemolytic Streptococcal infection. The disease may present with variable symptoms and signs. Cases: The first case is an 8-year-old boy with arthritis and previous streptococcal infection. The treatment was glucocorticoids and antibiotics. The second case is a 17-year-old boy with prolonged fever and palpitations. Carditis was found on echocardiography. The treatment was aspirin and antibiotics. The third case is a 17-year-old girl with a congenital heart defect. The patient had severe carditis as well as arthritis. The treatment was diuretics, antibiotics, steroids, antiarrhythmics, and beta-blockers. Management differed in each case, but all had favorable outcomes. Conclusion: Clinicians should be aware of the various manifestations of rheumatic fever and come to a swift diagnosis to initiate prompt treatment, which thus can decrease disease burden and morbidity.
Relationship between Neutrophil-Lymphocyte Ratio and Type of Febrile Seizures Event Putra, Agus Indra Yudhistira Diva; Mustika, Putu Pradnyanita; Suryawan, Wayan Bikin
International Journal of Integrated Health Sciences Vol 13, No 2 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n2.4291

Abstract

Background: Febrile seizure is a common neurological condition affecting children. Complete blood count (CBC)  is often used as the initial test to help determine the etiology of fever based on hematology parameters in the emergency ward.Objective: To analyze the relationship between neutrophil-lymphocyte ratio (NLR) and the type of febrile seizure  among pediatric patients admitted to Wangaya General Hospital Denpasar, Indonesia.Methods: A cross-sectional design was implemented on a study using medical records of 44 children aged 6 month-5 years old admitted to the Wangaya Hospital between January 1, 2023, and September 8, 2024. Participants were grouped into simple and complex febrile seizures.Results: Among patients who experienced the first febrile seizure, the complex type accounted for most hospitalizations (n=33, 75.0%). The majority of cases occurred in children aged ≤24 months (n=32, 72.7%) with a temperature of >38°C (n=27, 61.4%). Seizure duration was ≤15 minutes in most cases (n=41, 93.9%), with upper Respiratory Infection being the most common etiology (n=20, 45.5%). NLR did not differ significantly between the simple and complex febrile seizures (P value =0.894), with a prevalence ratio (PR) of 1.1. Additionally, leukopenia, lymphocytopenia, and neutrophilia were observed in 28 (63.6%), 23 (52.3%), and 24 (54.5%) patients, respectively.Conclusion: There is no significant relationship between NLR and the type of first febrile seizures. Seizures are more frequently observed in males, particularly those aged 6-24 months with body temperature exceeding 38°C. The mean NLR of 2.78 ± 2.38 and upper respiratory infection are the most frequently associated conditions.
Co-Authors Andre Gunawan Cynthia Cynthia Gozali, Ferry I Wayan Bikin Suryawan Liman, Claudia Natasha Predani, Ni Luh Putu Diaswari Putra, Agus Indra Yudhistira Diva Suriadi, Regina Tedja, I Gusti Ayu Wiradari Wayan Bikin Suryawan, Wayan Bikin Wielim, Edbert