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All Journal Biology, Medicine, & Natural Product Chemistry
Afrilliana, Friska
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

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The Improvement of Heart Histopathology of Hypercholesterolemic Mice using Sidempuan Salacca (Salacca sumatrana) Vinegar Atifah, Yusni; Az zahra, Firda; Helendra, Helendra; Lubis, Jalilah Azizah; Afrilliana, Friska
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.161-166

Abstract

Hypercholesterolemic, a condition characterized by excess cholesterol content, can lead to coronary heart disease, atherosclerosis, and high-risk heart tissue degeneration. Current drugs, like simvastatin and pravastatin, focus on lowering cholesterol levels without addressing tissue degeneration. This study aimed to determine the effectiveness of sidempuan salacca vinegar in improving cardiac tissue degeneration in hypercholesterolemic mice. The experimental research involved two groups, the treatment group given different doses of sidempuan salacca vinegar and the control group. Histopathological observations showed improvement in cardiac tissue degeneration in hypercholesterolemic mice after treatment with salacca vinegar. The administration of salacca vinegar could serve as a reference for developing alternative hypercholesterolemic drugs that address both cholesterol levels and heart degeneration.
Co-Authors Atifah, Yusni Az zahra, Firda Helendra Helendra Jalilah Azizah Lubis