Biology, Medicine, & Natural Product Chemistry
Vol 14, No 1 (2025)

The Improvement of Heart Histopathology of Hypercholesterolemic Mice using Sidempuan Salacca (Salacca sumatrana) Vinegar

Atifah, Yusni (Unknown)
Az zahra, Firda (Unknown)
Helendra, Helendra (Unknown)
Lubis, Jalilah Azizah (Unknown)
Afrilliana, Friska (Unknown)



Article Info

Publish Date
18 May 2025

Abstract

Hypercholesterolemic, a condition characterized by excess cholesterol content, can lead to coronary heart disease, atherosclerosis, and high-risk heart tissue degeneration. Current drugs, like simvastatin and pravastatin, focus on lowering cholesterol levels without addressing tissue degeneration. This study aimed to determine the effectiveness of sidempuan salacca vinegar in improving cardiac tissue degeneration in hypercholesterolemic mice. The experimental research involved two groups, the treatment group given different doses of sidempuan salacca vinegar and the control group. Histopathological observations showed improvement in cardiac tissue degeneration in hypercholesterolemic mice after treatment with salacca vinegar. The administration of salacca vinegar could serve as a reference for developing alternative hypercholesterolemic drugs that address both cholesterol levels and heart degeneration.

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Journal Info

Abbrev

BIOMEDICH

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for ...