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All Journal Medula Journal Medical Informatics Technology
Camilia, Anita
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Computer Science & IT Dentistry Education Engineering Medicine & Pharmacology Neuroscience Public Health

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The role of Salmon DNA in Skin Regeneration and Anti-Aging Camilia, Anita; AP, Gadila; Dwiputri, Maliya Finda; Arief, Skolastika Faustina Ivana; Setyadi, Yudha Putra
Journal Medical Informatics Technology Volume 3 No. 2, June 2025
Publisher : SAFE-Network

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37034/medinftech.v3i2.95

Abstract

Salmon DNA, particularly its polydeoxyribonucleotide (PDRN) content, has attracted attention in dermatology due to its potential in skin regeneration and anti-aging applications. This review aims to summarize various research findings on the effectiveness of PDRN. The study was conducted through a literature review of articles published between 2016 and 2023. Findings indicate that PDRN works by activating adenosine A2a receptors, stimulating angiogenesis, cell proliferation, and reducing inflammation. Its combination with vitamin C and niacinamide enhances antioxidant effects and helps preserve the extracellular matrix. Furthermore, the use of long-chain polynucleotide fillers has been shown to significantly improve pore size, skin texture, wrinkles, and sagging, with minimal side effects. In conclusion, PDRN from salmon DNA is a promising bioactive agent for skin rejuvenation, wound healing, and anti-aging therapy in modern dermatological practice.
Overview of Personal Protective Equipment Use Among Oil Palm Farmers in Simpang Pematang Subdistrict, Mesuji Regency Camilia, Anita; Saftarina, Fitria; Febriani, Wiwi; Larasati, TA
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1437

Abstract

The use of personal protective equipment (PPE) is an essential effort in preventing occupational health and safety risks, especially for farmers working in the plantation sector. This study aims to analyze the use of PPE among oil palm farmers in Simpang Pematang Subdistrict, Mesuji Regency. The research employs a cross-sectional approach involving 105 oil palm farmers selected through purposive sampling. Data were collected using questionnaires and analyzed univariately. The findings show that the level of compliance with PPE usage is still low, with only 48.6% of farmers consistently adhering to PPE usage procedures. The use of specific PPE items such as masks and protective glasses is particularly low, at just 13.3% and 5.7%, respectively. The main barriers to PPE use include farmers' lack of understanding about its importance, limited availability of PPE, and misconceptions about its comfort. This study concludes that strategic efforts are needed to improve PPE compliance through education, outreach programs, and the provision of adequate PPE.
Co-Authors AP, Gadila Arief, Skolastika Faustina Ivana Dwiputri, Maliya Finda Fitria Saftarina Setyadi, Yudha Putra TA Larasati Wiwi Febriani