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All Journal Biology, Medicine, & Natural Product Chemistry Biosel: Biologi Science and Education
Heldiana, Fitria
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Energy Environmental Science Medicine & Pharmacology Public Health

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Analisis Fitokimia terhadap Senyawa Aktif dalam Daun Carica Papaya sebagai Dasar Formulasi Kapsul Kurniadi, Helman; Syafitri, Ulfah Eka; Alfiana, Dessinta; Framisa, Mentari; Hairani; Heldiana, Fitria
Biosel Biology Science and Education Vol. 14 No. 1 (2025): BIOSEL (Biology Science and Education: Jurnal Penelitian Sains dan Pendidikan)
Publisher : INSTITUT AGAMA ISLAM NEGERI AMBON

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33477/bs.v14i1.9101

Abstract

Papaya leaves (Carica papaya L.) are rich in secondary metabolites with pharmacological potential as antioxidants, anti-inflammatories, and antimicrobials. This study aimed to identify bioactive compounds in papaya leaves, develop simplicia and extracts as a basis for capsule formulation, and evaluate the characteristics and stability of the resulting capsules. The methods used included simplicia preparation, extraction using maceration with 70% ethanol, phytochemical analysis using specific reagent tests, and capsule formulation with appropriate excipients. The results showed that papaya leaf simplicia had a moisture content of ≤ 5%, extraction yielded a rendement of 9.6%, and active compounds such as alkaloids, flavonoids, and polyphenols were detected. Capsule formulations containing papaya leaf extract showed good characteristics, with a dissolution time reaching 80% within 30 minutes, and good stability during storage. Papaya leaf extract can be developed as a stable, effective, and pharmaceutically standardized herbal phytopharmaceutical capsule preparation to support natural medicine. Keywords: C. papaya, Secondary Metabolites, Maceration, Herbal Capsule, Phytochemistry
Medicinal Plant Use by Traditional Healers in the Muaro Jambi Temple Complex Kurniadi, Helman; Aminuddin, Aminuddin; Heldiana, Fitria
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.167-175

Abstract

Traditional medicinal knowledge plays an essential role in community health practices, yet much of it remains undocumented and at risk of being lost. This study investigated the ethnobotanical knowledge of traditional healers in the cultural landscape surrounding Candi Muaro Jambi, Indonesia. From April to July 2025, interviews were conducted with seven key informants recognized for their expertise in traditional healing. Information on plant names, parts used, preparation methods, routes of application, and treated ailments was collected and verified through botanical identification. A total of 98 medicinal plant species were documented, with leaves most frequently used (45.9%), followed by fruits, stems, seeds, bark, or latex (30.6%), and roots, rhizomes, or tubers (23.5%). Boiling was the predominant preparation method, valued for its simplicity and effectiveness in extracting water-soluble compounds. The recorded remedies addressed a wide spectrum of health conditions, including infections, inflammatory diseases, metabolic disorders, and respiratory problems, applied both orally and topically. These findings highlight the cultural importance and pharmacological potential of local ethnomedicinal practices, providing a valuable foundation for future drug discovery and biodiversity conservation.
Co-Authors Alfiana, Dessinta Aminuddin Aminuddin Framisa, Mentari Hairani Syafitri, Ulfah Eka