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All Journal Jurnal Biologi Tropis SALUT: Journal of Social and Education
Kanata, Nur Ramdhani
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Social Sciences Other

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Literature Review: CRISPR-Cas 9 Genetic Engineering as Breast Cancer Therapy Salsabila, Pisqiantin Aenan; Bulkis, Nanda; Praditama, Lalu Denendra; Kanata, Nur Ramdhani; Maghfirahandini, Reivirly Khairadaty; Sunarwidhi, Anggit Listyacahyani
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8957

Abstract

Cancer is a disease characterized by uncontrolled abnormal cell growth, originating from cancer stem cells. These cells form a side population with stemness properties similar to normal stem cells, have high tumorigenicity, and contribute to the development of cancer. Among all cases, breast cancer is one of the causes of cancer death in women worldwide, estimated to reach 28% of new cancers. The application of one of the genetic engineering techniques in the form of CRISPR / Cas9 which can be used as an alternative choice in optimizing breast cancer therapy. This literature review aims to determine CRISPR-Cas 9 Genetic Engineering as Breast Cancer Therapy. This journal review method is through searching for articles from databases such as PubMed, ScienceDirect, and Google Scholar using relevant keywords, namely breast cancer therapy, Genetic Engineering, CRISPR / Cas9 Technique. The results obtained show something promising in the use of one of the genetic engineering technologies in the form of the CRISPR / Cas9 technique which is able to weaken or suppress genetic activity related to the continuity of growth and development of breast cancer cells. In conclusion, CRISPR/Cas9 technology shows promising potential in breast cancer therapy with its ability to inhibit the expression of certain genes that contribute to the growth, invasion, and metastasis of cancer cells.
Pancasila Sebagai Jiwa Kepribadian Bangsa  : Relevansinya Bagi Generasi Muda di Era Globalisasi Mutthoimah, Ulfatul; Anugraheni, Audina Filsa Nur; Putri, Baiq Haura Audina Ananta; Pramudya, Muhammad Zaidan; Hawarikatun, Baiq; Kanata, Nur Ramdhani; Maulira, Dinda Ayu
Journal of Social and Education Vol. 2 No. 1 (2025): Journal of Social and Education
Publisher : Lembaga Riset dan Publikasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/pe3jv258

Abstract

Pancasila sebagai dasar negara sekaligus jiwa kepribadian bangsa Indonesia menghadapi tantangan serius di era globalisasi, terutama dalam internalisasi nilai-nilainya oleh generasi muda. Arus globalisasi yang membawa budaya asing, gaya hidup individualistik, serta kemajuan teknologi informasi telah berdampak pada menurunnya pemahaman dan pengamalan nilai-nilai Pancasila. Artikel ini bertujuan untuk menganalisis tingkat pemahaman, sikap, serta relevansi Pancasila bagi generasi muda. Metode penelitian dilakukan melalui studi literatur dengan teknik analisis isi yang mengkaji secara mendalam tema utama, kecenderungan berpikir, serta temuan penting dari literatur. Hasil kajian menunjukkan bahwa meskipun sebagian besar generasi muda menyadari pentingnya Pancasila, masih banyak yang belum menerapkannya secara konsisten dalam kehidupan sehari-hari. Oleh karena itu, dibutuhkan strategi edukatif yang adaptif seperti pendidikan karakter berbasis nilai Pancasila, pemanfaatan media digital, serta peran aktif keluarga, institusi pendidikan, dan masyarakat. Penanaman nilai Pancasila sejak dini menjadi langkah strategis untuk memperkuat identitas nasional dan ketahanan ideologi bangsa di tengah derasnya pengaruh globalisasi.
Co-Authors Anugraheni, Audina Filsa Nur Bulkis, Nanda Hawarikatun, Baiq Maghfirahandini, Reivirly Khairadaty Maulira, Dinda Ayu Mutthoimah, Ulfatul Praditama, Lalu Denendra Pramudya, Muhammad Zaidan Putri, Baiq Haura Audina Ananta Salsabila, Pisqiantin Aenan Sunarwidhi, Anggit Listyacahyani