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Bulkis, Nanda
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PENATALAKSANAAN HEPATITIS B : KAJIAN PUSTAKA Yasykurah, Malva Marshaniswa; Dalila, Virga Fathiya; Nugrahani, Baiq Dwiyan; Bulkis, Nanda; Ananta, Muhammad Naufal Farras; Nurhidayati
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.35930

Abstract

Hepatitis B merupakan masalah kesehatan global yang serius, hepatitis B menyumbang sekitar 80% kasus karsinoma hepatoseluler primer dan menjadi penyebab kanker tertinggi kedua setelah rokok. Penatalaksanaan hepatitis B awalnya menggunakan interferon, kemudian hadir obat golongan baru yaitu analog nukelosida (NA) seperti lamivudin, dan seiring perkembangannya ditemukan obat baru seperti adefovir, entecavir, telbivudine dan tenofovir. Tingginya prevalensi infeksi hepatitis B sering kali berkaitan dengan rendahnya tingkat keberhasilan terapi pada pasien. Hasil pengobatan hepatitis B hingga saat ini masih belum memadai, sehingga beberapa kasus dapat berkembang menjadi sirosis hati dan kanker hati.  Oleh karena itu, tinjauan ini membahas mengenai penatalaksanaan hepatitis B. Kajian pustaka dilakukan dengan penelusuran pustaka dengan pencarian online mengenai regimen terapi hepatitis B melalui situs pencarian Google, Google Scholar, Research Gate. Penelusuran pustaka menggunakan kata kunci “Treatment of Hepatitis B Article”. Terdapat perbedaan terapi pada hepatitis B akut dan kronik. Pada kondisi akut, tujuan terapi hepatitis B adalah untuk meningkatkan kenyamanan pasien. Sedangkan pada kondisi kronis, tujuan terapinya adalah untuk mengurangi risiko sirosis, kanker hati, dan meningkatkan kelangsungan hidup jangka panjang. Terapi farmakologi yang digunakan pada hepatitis B selama lima tahun terakhir yaitu golongan analog nukelosida, analog nukleotida dan interferon. Golongan analog nukleosida terdiri dari lamivudin, telbivudin, dan entecavir. Sedangkan golongan analog nukleotida terdiri dari tenofovir disoproxil fumarate, tenofovir alafenamid, dan adefovir.
THE KNOWLEDGE LEVEL STUDENTS OF THE FACULTY OF ECONOMICS AND BUSINESS, UNIVERSITY OF MATARAM REGARDING CLEAN AND HEALTHY LIVING BEHAVIOR BULKIS, NANDA; Puspitasari, Candra Eka
Jurnal Kesehatan Tambusai Vol. 6 No. 2 (2025): JUNI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i2.41979

Abstract

PHBS merupakan perilaku kesehatan seorang individu yang dilakukan secara sadar yang berfungsi memelihara kesehatan atau berperan dalam kegiatan kesehatan. Setiap orang mempunyai kesempatan yang sama mengenai Kesehatan. PHBS penting untuk membiasakan hidup di lingkungan yang bersih. Kesehatan merupakan salah satu kebutuhan manusia untuk dapat melakukan aktivitas. Kesehatan dapat mendukung pendidikan kemudian pendidikan akan mendukung status kesehatan. Menjaga kesehatan dapat dilakukan dengan menerapkan PHBS (Perilaku Hidup Bersih dan Sehat). Tujuan penelitian untuk mengetahui tingkat pengetahuan mahasiswa Fakultas Ekonomi dan Bisnis Universitas Mataram tentang Perilaku Hidup Bersih dan Sehat. Penelitian ini merupakan penelitian observasional dengan rancangan cross sectional. Lokasi pengambilan sampel dilakukan di Fakultas Ekonomi dan Bisnis Universitas Mataram. Jumlah populasi mahasiswa FEB Unram sebanyak 6790 orang, selanjutnya dilakukan perhitungan sampel minimum dengan rumus slovin dengan selang kepercayaan 10% pada populasi yang diketahui dan diperoleh minimum 100 responden dengan memperoleh 107 responden. Data diolah dengan menggunakan statistik deskriptif, selanjutnya dilakukan uji lanjutan dengan uji statistik yaitu Kruskal-Wallis dan Maan Whitney untuk melihat karakteristik responden. Hasil pengujian menunjukkan bahwa tidak terdapat perbedaan yang signifikan tingkat pengetahuan PHBS mahasiswa FEB berdasarkan jenis kelamin, usia dan program studi (p=0,317; p=0,416; p=0,423). Sebanyak 99,07% responden termasuk dalam kategori tingkat pengetahuan tinggi. Jadi dapat disimpulkan bahwa tingkat pengetahuan mahasiswa Fakultas Ekonomi dan Bisnis terhadap PHBS termasuk dalam kategori tinggi.
PEMBUATAN COOKIES DAUN MANGROVE (Rhizophora mucronata) DALAM UPAYA OPTIMALISASI PEMANFAATAN TANAMAN MANGROVE Attaya, Kalisa; Maziya, Raehanul; Amalia, Marshanda Fitri; Bulkis, Nanda; Sutanti, Baiq Novia Rahmadita; Permatasari, Lina
Jurnal Pepadu Vol 6 No 1 (2025): Jurnal Pepadu
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v6i1.6150

Abstract

An unhealthy lifestyle can lead to increased production of free radicals as a byproduct of metabolism. This condition can be mitigated by antioxidants. Rhizophora mucronata offers various health benefits, including its role as an antioxidant. However, public utilization of Rhizophora mucronata remains limited. To enhance its appeal, Rhizophora mucronata was processed into mangrove leaf cookies, making it more convenient for consumption. The objective of this activity was to optimize the utilization of mangrove plants. The activity was conducted on December 20, 2024, at the Meninting Village Hall, Batulayar Subdistrict, West Lombok Regency, with 20 participants. The implementation method included training sessions comprising the delivery of materials on mangrove plants and the process of making mangrove cookies, followed by hands-on cookie-making training. The participants were highly enthusiastic throughout the program, and the material was well understood, as evidenced by the quiz results provided during the session.
Literature Review: CRISPR-Cas 9 Genetic Engineering as Breast Cancer Therapy Salsabila, Pisqiantin Aenan; Bulkis, Nanda; Praditama, Lalu Denendra; Kanata, Nur Ramdhani; Maghfirahandini, Reivirly Khairadaty; Sunarwidhi, Anggit Listyacahyani
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8957

Abstract

Cancer is a disease characterized by uncontrolled abnormal cell growth, originating from cancer stem cells. These cells form a side population with stemness properties similar to normal stem cells, have high tumorigenicity, and contribute to the development of cancer. Among all cases, breast cancer is one of the causes of cancer death in women worldwide, estimated to reach 28% of new cancers. The application of one of the genetic engineering techniques in the form of CRISPR / Cas9 which can be used as an alternative choice in optimizing breast cancer therapy. This literature review aims to determine CRISPR-Cas 9 Genetic Engineering as Breast Cancer Therapy. This journal review method is through searching for articles from databases such as PubMed, ScienceDirect, and Google Scholar using relevant keywords, namely breast cancer therapy, Genetic Engineering, CRISPR / Cas9 Technique. The results obtained show something promising in the use of one of the genetic engineering technologies in the form of the CRISPR / Cas9 technique which is able to weaken or suppress genetic activity related to the continuity of growth and development of breast cancer cells. In conclusion, CRISPR/Cas9 technology shows promising potential in breast cancer therapy with its ability to inhibit the expression of certain genes that contribute to the growth, invasion, and metastasis of cancer cells.
PEMBUATAN COOKIES DAUN MANGROVE (Rhizophora mucronata) DALAM UPAYA OPTIMALISASI PEMANFAATAN TANAMAN MANGROVE Attaya, Kalisa; Maziya, Raehanul; Amalia, Marshanda Fitri; Bulkis, Nanda; Sutanti, Baiq Novia Rahmadita; Permatasari, Lina
Jurnal Pepadu Vol 6 No 1 (2025): Jurnal Pepadu
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v6i1.6150

Abstract

An unhealthy lifestyle can lead to increased production of free radicals as a byproduct of metabolism. This condition can be mitigated by antioxidants. Rhizophora mucronata offers various health benefits, including its role as an antioxidant. However, public utilization of Rhizophora mucronata remains limited. To enhance its appeal, Rhizophora mucronata was processed into mangrove leaf cookies, making it more convenient for consumption. The objective of this activity was to optimize the utilization of mangrove plants. The activity was conducted on December 20, 2024, at the Meninting Village Hall, Batulayar Subdistrict, West Lombok Regency, with 20 participants. The implementation method included training sessions comprising the delivery of materials on mangrove plants and the process of making mangrove cookies, followed by hands-on cookie-making training. The participants were highly enthusiastic throughout the program, and the material was well understood, as evidenced by the quiz results provided during the session.
Co-Authors Amalia, Marshanda Fitri Ananta, Muhammad Naufal Farras Attaya, Kalisa Candra Eka Puspitasari Dalila, Virga Fathiya Kanata, Nur Ramdhani Maghfirahandini, Reivirly Khairadaty Maziya, Raehanul Nugrahani, Baiq Dwiyan Nurhidayati Permatasari, Lina Praditama, Lalu Denendra Salsabila, Pisqiantin Aenan Sunarwidhi, Anggit Listyacahyani Sutanti, Baiq Novia Rahmadita Yasykurah, Malva Marshaniswa